第一项研究是一项数据库分析，发现同时服用吡氯格雷和PPI药物的患者心血管系统发病增加，另一项称作CREDO的研究没发现联合用药有副作用。
The first study, a database analysis, found an increase in cardiac events in patients taking clopidogrel and a PPI. A second study, called CREDO, found no adverse effects from the combination.
你在服用抗凝药物（比如华法林，肝素）或者抗血小板聚集药物（阿司匹林或氯吡格雷）——一般情况下，在结肠镜检前应明停止服用这些药物，以防出血不止。
Are taking any blood-thinning drugs (such as warfarin or heparin) or antiplatelet medication (such as aspirin or clopidogrel)
在一种老鼠中，氯吡格雷控制住对肾脏的危害，而对肾脏的危害是狼疮所造成的常见后果，有时这种后果也是致命的。
In one strain of the mice, clopidogrel curbed the amount of kidney damage, a common and sometimes lethal consequence of the disease.
研究问题：血小板反跳存在的证据是什么？它能通过氯吡格雷逐渐停药而减弱呢？
Study Question: What is the evidence that a platelet rebound exists, and can it be attenuated by clopidogrel tapering?
阿司匹林过敏的患者，推荐氯吡格雷(1a级)。
For patients who are allergic to aspirin, we recommend clopidogrel (Grade 1a).
对于股骨颈骨折患者等待手术时是否应常规停用氯吡格雷，目前尚无指导和推荐。
No guidelines or recommendations currently exist regarding the routine discontinuation of clopidogrel in patients with fracture of the femoral neck awaiting surgery.
背景：氯吡格雷是一种导致凝血时间延长的抗血小板药物。
Background: Clopidogrel is an anti-platelet agent which causes an increase in bleeding time.
联合应用氯吡格雷和其他抗血小板药物，已经越来越多出现在的急性股骨颈骨折患者的医疗处方中。
An increasing number of patients presenting with an acute femoral neck fracture take clopidogrel in combination with other anti-platelet agents as regular prescription medication.
结论：作者推断氯吡格雷逐渐减量没有导致氯吡格雷停药后更低的血小板聚合值。
Conclusions: The authors concluded that tapering of clopidogrel does not result in lower platelet aggregation values after clopidogrel withdrawal.
两组间差异主要源于使用氯吡格雷减低中风发生率。
The difference was primarily due to a reduction in the rate of stroke with clopidogrel.
有一种方法是注射可溶性CD39，但是会和阿司匹林或氯吡格雷一样存在抗血小板的副作用。
One way is to infuse a soluble form of CD39 which could have some side effects according to all the antiplatelet therapies like aspirin or clopidogrel.
总之，停用氯吡格雷后的血小板聚集值不支持氯吡格雷停药后存在血小板反跳现象。
Overall, the course of platelet aggregation values after clopidogrel cessation does not support the existence of a rebound phenomenon of platelets after discontinuation of clopidogrel.
目的观察两种硫酸氢氯吡格雷在经皮冠状动脉介入治疗中的临床应用效果。
Objective To investigate the clinical effect of two kinds of clopidogrel on percutaneous coronary intervention.
目的：观察氯吡格雷对兔髂腹动脉球囊损伤后血管内皮功能及平滑肌细胞的影响。
Objective: To investigate the effects of clopidogrel on the iliac arterial endothelial function and smooth muscle cell in rabbits following balloon injury in iliac artery.
《国际循环》：对于急性冠脉综合症(acs)合并房颤(AF)的患者，可能需要接受阿司匹林、氯吡格雷以及华法林治疗，这可能会导致致死性的出血情况。关于这个问题您有何意见？
International Circulation: For the patient with ACS and AF, they might accept aspirin, clopidogrel and warfarin, which are related to fatal bleeding. What is your opinion about this?
吸烟诱导CYP1A2而且可能因此增强氯吡格雷转化为其活性代谢产物。
Cigarette smoking induces CYP1A2 and may, therefore, enhance the conversion of clopidogrel to its active metabolite.
目的：观察氯吡格雷治疗急性非st段抬高心肌梗死(NSTEMI)的临床疗效及安全性。
Objective: To observe the clinical effect and safety in treatment of non-ST elevation myocardial infarction (NSTEMI) with clopidogrel.
目的：研究目的是为了确定哪些因素会降低氯吡格雷对心血管病(CVD)患者的血小板抑制作用(PI)。
Objectives: The goal of this study was to identify factors associated with lower platelet inhibition (PI) with clopidogrel in subjects with cardiovascular disease (CVD).
不管是否服用氯吡格雷，依诺肝素都较普通肝素具有更明显的安全性和有效性。
The significantly improved safety and efficacy profile of enoxaparin versus unfractionated heparin was maintained regardless of clopidogrel administration.
氯吡格雷的疗效优于阿司匹林，但因其价格昂贵，目前仅在阿司匹林不能耐受或阿司匹林无效者中使用。
The efficacy of clopidogrel is better than aspirin, but because its price is much expensive, now it is only used in patients who cannot tolerate aspirin or no response to it.
并且同时应用氯吡格雷和依诺肝素的患者心血管事件的发生率最低。
The rates of adverse cardiovascular events were lowest in patients treated with both clopidogrel and enoxaparin, the investigators report.
是时候对氯吡格雷治疗患者选择性检测基因谱吗？
Is the time now right for selective gene profiling in clopidogrel patients?
提示血小板聚集试验为氯吡格雷剂量监测简捷、实用、有效的方法之一。
The blood platelet aggregation is a simple, effective and practical platelet function experiment for the clopidogrel dosage monitor.
在804名患者中有105位(13%)对氯吡格雷无效。
Of 804 patients, 105 (13%) were not responsive to clopidogrel.
目的研究氯吡格雷治疗进展型缺血性脑卒中的疗效。
Objective To investigate the therapeutic effect of clopidogrel on progressive ischemic cerebral apoplexy.
目的研究氯吡格雷治疗进展型缺血性脑卒中的疗效。
Objective To investigate the therapeutic effect of clopidogrel on progressive ischemic cerebral apoplexy.
应用推荐