药物支架病人应该服用氯吡格雷多长时间？
所有病人治疗前都在服用阿司匹林和氯吡格雷。
阿司匹林过敏的患者，推荐氯吡格雷(1a级)。
For patients who are allergic to aspirin, we recommend clopidogrel (Grade 1a).
背景：已有研究显示氯吡格雷治疗反应的变异性。
Background: Response variability to clopidogrel therapy has been demonstrated.
是时候对氯吡格雷治疗患者选择性检测基因谱吗？
Is the time now right for selective gene profiling in clopidogrel patients?
本发明涉及硫酸氢氯吡格雷固体制剂的制备工艺。
The invention relates to a preparation process of clopidogrel bisulfate solid preparation.
质子泵抑制剂和氯吡格雷的相互作用：是真是假？
Proton Pump Inhibitor and Clopidogrel Interaction: Fact or Fiction?
两组间差异主要源于使用氯吡格雷减低中风发生率。
The difference was primarily due to a reduction in the rate of stroke with clopidogrel.
目的研究氯吡格雷治疗进展型缺血性脑卒中的疗效。
Objective To investigate the therapeutic effect of clopidogrel on progressive ischemic cerebral apoplexy.
本发明还提供了所述的硫酸氢氯吡格雷片剂的制备方法。
The invention also provides a preparation method of the clopidogrel bisulfate tablet.
实验表明，本发明的硫酸氢氯吡格雷片剂的稳定性优异。
Experiment results show that the stability of the clopidogrel bisulfate tablet of the invention is excellent.
背景：氯吡格雷是一种导致凝血时间延长的抗血小板药物。
Background: Clopidogrel is an anti-platelet agent which causes an increase in bleeding time.
观察CS术后1个月复发缺血事件与氯吡格雷抵抗的关系。
To investigate the relationship between the recurrence of ischemic events and clopidogrel resistance in 1 month after CS.
在804名患者中有105位(13%)对氯吡格雷无效。
Of 804 patients, 105 (13%) were not responsive to clopidogrel.
氯吡格雷抵抗包括对氯吡格雷无反应和对氯吡格雷低反应。
Clopidogrel resistance showed no response or low response to clopidogrel.
结论：PCI介入治疗的患者中存在部分氯吡格雷抵抗者。
Conclusions: Clopidogrel resistance occurs in some of the patients undergoing PCI.
目标：本研究的目的是探讨吸烟对血小板对氯吡格雷反应的作用。
Objectives: the purpose of this study was to examine the effect of cigarette smoking on the platelet response to clopidogrel.
并且同时应用氯吡格雷和依诺肝素的患者心血管事件的发生率最低。
The rates of adverse cardiovascular events were lowest in patients treated with both clopidogrel and enoxaparin, the investigators report.
提示血小板聚集试验为氯吡格雷剂量监测简捷、实用、有效的方法之一。
The blood platelet aggregation is a simple, effective and practical platelet function experiment for the clopidogrel dosage monitor.
吸烟诱导CYP1A2而且可能因此增强氯吡格雷转化为其活性代谢产物。
Cigarette smoking induces CYP1A2 and may, therefore, enhance the conversion of clopidogrel to its active metabolite.
目的观察两种硫酸氢氯吡格雷在经皮冠状动脉介入治疗中的临床应用效果。
Objective To investigate the clinical effect of two kinds of clopidogrel on percutaneous coronary intervention.
不管是否服用氯吡格雷，依诺肝素都较普通肝素具有更明显的安全性和有效性。
The significantly improved safety and efficacy profile of enoxaparin versus unfractionated heparin was maintained regardless of clopidogrel administration.
因此，多项研究表明当氯吡格雷和奥美拉唑同时给予时，氯吡格雷的疗效降低。
As a result, studies have shown that when clopidogrel and omeprazole are taken together, the effectiveness of clopidogrel is reduced.
目的：观察氯吡格雷对兔髂腹动脉球囊损伤后血管内皮功能及平滑肌细胞的影响。
Objective: To investigate the effects of clopidogrel on the iliac arterial endothelial function and smooth muscle cell in rabbits following balloon injury in iliac artery.
研究问题：血小板反跳存在的证据是什么？它能通过氯吡格雷逐渐停药而减弱呢？
Study Question: What is the evidence that a platelet rebound exists, and can it be attenuated by clopidogrel tapering?
结论：作者推断氯吡格雷逐渐减量没有导致氯吡格雷停药后更低的血小板聚合值。
Conclusions: The authors concluded that tapering of clopidogrel does not result in lower platelet aggregation values after clopidogrel withdrawal.
对于股骨颈骨折患者等待手术时是否应常规停用氯吡格雷，目前尚无指导和推荐。
No guidelines or recommendations currently exist regarding the routine discontinuation of clopidogrel in patients with fracture of the femoral neck awaiting surgery.
总之，停用氯吡格雷后的血小板聚集值不支持氯吡格雷停药后存在血小板反跳现象。
Overall, the course of platelet aggregation values after clopidogrel cessation does not support the existence of a rebound phenomenon of platelets after discontinuation of clopidogrel.
总之，停用氯吡格雷后的血小板聚集值不支持氯吡格雷停药后存在血小板反跳现象。
Overall, the course of platelet aggregation values after clopidogrel cessation does not support the existence of a rebound phenomenon of platelets after discontinuation of clopidogrel.
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