乏氧诱导因子(HIF)是乏氧应答中起重要作用的转录因子，一直是乏氧研究的焦点。
Hypoxia-inducible factor (HIF) is an important transcriptional factor, which plays crucial role in response to hypoxia.
低氧诱导因子1 (HIF - 1)是重要的氧依赖性核转录因子，低氧条件下能上调多个靶基因表达以减少缺氧性损伤。
Hypoxia inducible factor-1 (HIF-1) is a key oxygen-dependent transcription factor that up-regulates many protective genes against hypoxia-induced injury.
结果细胞因子、辐射、氧自由基等可诱导血管内皮细胞凋亡，导致血管损伤；
Results Cytokine, radiation could induce apoptosis of endothelial cells, and caused vascular damage.
此外，内毒素诱导许多破坏性和炎症因子快速升高，包括活性氧(自由基)、一氧化氮和脂肪代谢产物。
In addition, the endotoxin induced a rapid rise in several destructive and inflammatory factors, including reactive oxygen species (free radicals) and products of nitric oxide and fat metabolism.
此外，内毒素诱导许多破坏性和炎症因子快速升高，包括活性氧(自由基)、一氧化氮和脂肪代谢产物。
In addition, the endotoxin induced a rapid rise in several destructive and inflammatory factors, including reactive oxygen species (free radicals) and products of nitric oxide and fat metabolism.
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