目的优选肝靶向氧化苦参碱毫微粒的制备工艺。
Objective TO optimize the process for preparing liver - targeted oxymatrine nanoparticles (LTON).
目的：观察氧化苦参碱(omt)对大鼠血压的影响。
Objective To investigate the effects of oxymatrine (OMT) on blood pressure in rats.
目的制备氧化苦参碱缓释片剂，并评价其体外释药特性。
OBJECTIVE To prepare oxymatrine sustained-release tablets and evaluate the drag release property.
结论氧化苦参碱对大鼠急性心肌缺血损伤具有保护作用。
Conclusion Oxymatrine can protect against acute myocardial ischemia injury in rats.
目的评价泛昔洛韦、膦甲酸钠及氧化苦参碱的体外抗hbv作用。
Objective To determine and compare the anti-HBV effect of famciclovir, foscarnet and oxymatrine in vitro.
目的探讨氧化苦参碱治疗慢性乙型肝炎肝纤维化的效果及其机制。
Objective To evaluate the efficacy of oxymatrine on treating chronic hepatitis B with hepatic fibrosis and its mechanism.
结果在选择的几种提取工艺中，氧化苦参碱有向苦参碱转变的趋势。
Results in the selected extraction method, it had a trend that oxymatrine was converted to matrine.
结果：离体实验结果表明，氧化苦参碱可被人肠内菌代谢成苦参碱。
Result: Oxymatrine was transformed into matrine by human intestinal bacteria metabolism in vitro.
目的考察微滤-大孔树脂法精制苦参中氧化苦参碱、苦参总黄酮的效果。
Objective To study the effect of microfiltration-macroporous resin method in purification of oxymatrine and general flavone in sophora flavescens.
目的考察氧化苦参碱负电荷脂质体的处方和制备工艺，并研究其理化性质。
OBJECTIVE To investigate the formulation and preparation technique of anionic oxymatrine liposomes, and determine its physicochemical properties.
目的：研究苦参碱和氧化苦参碱降转氨酶活性，以期评价二者的肝保护作用。
Objective: to study effects of matrine and oxymatrine on level of serum aminotransferases for evaluating their activities to protect against hepatic damage.
处方中三白草对苦参中苦参碱及氧化苦参碱含量的影响大于蛇床子、火炭母。
The Influence of herba saururi was much higher than that of fructus cnidii and polygonum chinense on the content of matrine and oxymatrine.
目的：建立以高效液相色谱法测定癣净颗粒中苦参碱、氧化苦参碱含量的方法。
OBJECTIVE: To determine the contents of matrine and oxymatrine in Xuanjing granules by HPLC.
结果氧化苦参碱在肠道的吸收呈现一级吸收动力学特征且吸收机制为被动转运。
RESULTS: The absorption mechanism of oxymatrine complied with the passive diffusion and first order kinetics.
同时测定大鼠血清NO及脑组织中MPO含量以探讨氧化苦参碱的作用机制。
The NO content in serum and myeloperoxidase (MPO) content in brain tissue were determined to study the its mechanisms.
目的：建立用HPLC同时测定苦参药材中苦参碱和氧化苦参碱的含量测定方法。
Objective: to establish a high performance liquid chromatography (HPLC) method to determine the contents of matrine and oxymatrine in Sophora flavescens Ait.
通过建立鸭原代肝细胞-DHBV感染模型研究氧化苦参碱抗dhbv的作用。
A primary duck hepatocyte-DHBV (PDH-DHBV) infection model was established to investigate the antiviral effects of Oxymatrine (OM).
目的观察拉米夫定联合氧化苦参碱对抗慢性乙型肝炎(乙肝)肝纤维化的临床疗效。
Objective To observe the clinical effect of both oxymatrine and lamivudine on hepatic fibrosis induced by chronic hepatitis b.
结论在苦参的提取过程中，苦参碱和氧化苦参碱的转化对苦参提取工艺造成了影响。
Conclusion in the process of extracting, it had effect to transformation between matrine a...
方法采用大鼠在体肠灌流吸收实验，研究了氧化苦参碱的吸收部位和吸收动力学特征。
METHODS: The absorption kinetics and absorption site of oxymatrine were investigated using in situ perfusion method in rats.
目的：探讨氧化苦参碱(omt)对小鼠变态反应性接触性皮炎(ACD)的抑制作用。
Aim: To explore the inhibitive effects of oxymatrine (OMT) on allergic contact dermatitis (ACD) in mice.
本文综述了氧化苦参碱抗炎作用的研究概况及氧化苦参碱用于治疗牙周病的思路及展望。
This article reviews ammothamnine about its study situation of antiinflammatory effect and its idea and prospect in treating periodontal disease.
结果引种栽培的山豆根与野生山豆根不同部位的苦参碱及氧化苦参碱二者含量无明显差异。
ResultsThe matrine and oxymatrine of cultivated and field Shandougen have not difference in cultivation and field by UV.
通过对溶剂、提取次数、碱化条件的选择，用离子交换和重结晶的方法提取纯化氧化苦参碱。
Through selecting extracting solvent, extracting times and alkalinizing method, Oxymatrine is extracted and purified by ion-exchanging and re-crystallization.
目的从山豆根中精制苦参碱和氧化苦参碱，并以此为化学对照品对山豆根药材进行薄层色谱鉴别。
OBJECTIVE to isolate and purify the two alkaloids matrine and oxymatrine and then to identify the commercial medicinal material of "Shandougen" by TLC.
其主要活性物质是生物碱类和黄酮类，对其中的苦参碱和氧化苦参碱的药代动力学有初步的研究。
The compounds of Alkaloidss and flavonoids are main active composition, and there is a preliminary study on the pharmacokinetics of matrine alkaloids and oxymatrine.
氧化苦参碱对局灶性脑缺血大鼠的脑缺血性损伤具有明显的保护作用，抗炎可能为其作用途径之一。
OMT has protection against injury induced by cerebral ischemia in rats. The anti-inflammation effects may be one of the mechanisms.
氧化苦参碱是自中药苦参中提取的一种生物碱，本文就其对小鼠肝微粒体药物代谢酶的影响进行了探讨。
The effect of Oxymatrine(OMT), isolated from Sophora flavescens Ait, on the hepatic microsomal drug-metabolism enzyme have been investigated.
氧化苦参碱是自中药苦参中提取的一种生物碱，本文就其对小鼠肝微粒体药物代谢酶的影响进行了探讨。
The effect of Oxymatrine(OMT), isolated from Sophora flavescens Ait, on the hepatic microsomal drug-metabolism enzyme have been investigated.
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