目的制备氟伐他汀钠分散片。
Objective To prepare the dispersible tablet of Fluvastatin Sodium.
氟伐他汀抗氧化机制可能参与这个过程。
The anti-oxidation mechanism of fluvastatin may take part in this process.
目的：探讨氟伐他汀对纤溶系统的影响。
AIM: To explore the effect of fluvastatin on fibrinolysis system.
氟伐他汀治疗与不良事件发生率显著增加无关。
Fluvastatin therapy was not associated with a significant increase in the rate of adverse events.
目的：比较氟伐他汀和普伐他汀调整血脂的临床效果。
Objective: To compare the lipid - regulating effects of fluvastatin and pravastatin.
目的观察氟伐他汀对脑梗死患者颈动脉粥样硬化的影响。
Objective: To observe the effect of fluvastatin on carotid atherosclerosis in cerebral infarction patients.
目的：探讨放射性胸膜炎的发病机制及氟伐他汀的防治作用。
Objective: To explore the pathogenesis of radiation_induced pleurisy and its prevention and treatment with fluvastatin.
与氟伐他汀钠联合应用，对血管内皮细胞损伤有协同保护作用。
The protective effect of WEP on endothelial cells may be synergic with inhibitor of HMGCoA reductase such as fluvastatin sodium.
结论：行血管手术的患者，围术期氟伐他汀治疗可改善术后心脏结局。
Conclusions: in patients undergoing vascular surgery, perioperative fluvastatin therapy was associated with an improvement in postoperative cardiac outcome.
氟伐他汀酯经氢氧化钠(1n)水解制备得到降血脂药物氟伐他汀钠。
Fluvastatin sodium, a hypolipidemic drug, was prepared by ester hydrolysis from fluvastatin ester with 1n sodium hydroxide.
目的研究氟伐他汀对老年高血压病患者内皮依赖性血管舒张功能的影响。
Objective To investigate the effect of Fluvastatin on the endothelium dependent vasodilatation function in elder hypertensives.
结论氟伐他汀能抑制大鼠ami后左室重塑，改善血流动力学异常和左室功能。
Conclusion: Fluvastatin can prevent LVRM after ami in rats, improve hemodynamics and LV function.
目的研究氟伐他汀对冠心病的微循环及血液流变学影响，探讨其降脂以外的作用。
Objective To investigate the changes of the microcirculation and hemorheology after using fluvastatin and approach the effects on blood lipid level.
方法观察154例冠心病患者氟伐他汀治疗前后血脂及血液流变学、微循环的改变。
Methods Changes of blood lipid microcirculation and hemorheology before and after fluvastatin administration were observed and analysed in 154 cases with coronary artery disease.
目的观察氟伐他汀对正常血脂兔的心肌缺血再灌注损伤有无保护作用及其可能原因。
Aim To investigate the protective effect of fluvastatin on ischemia reperfusion myocardium in normocholesterolemic rabbit.
目的研究不同剂量氟伐他汀的短期预处理对兔心缺血再灌注损伤的保护作用及其机制。
Objective To investigate the effects and mechanism of different dosage of fluvastatin on the prevention of heart muscle ischemia reperfusion injury in rabbits.
此外，加用氟伐他汀进行干预，观察其对体外血管钙化的影响并探讨可能的作用机制。
Furthermore, to determine the effect of Fluvastatin on vascular calcification in vitro and its possible mechanism. Methods.
结论：作者的结论是，行血管手术的患者中，围术期氟伐他汀治疗可改善术后心脏结局。
Conclusions: the authors concluded that among patients undergoing vascular surgery, perioperative fluvastatin therapy was associated with an improvement in postoperative cardiac outcome.
背景：不良心脏事件常见于血管手术后。我们猜测围术期氟伐他汀治疗会改善术后结局。
Background: Adverse cardiac events are common after vascular surgery. We hypothesized that perioperative statin therapy would improve postoperative outcomes.
结果：共250名患者接受氟伐他汀治疗，247名接受安慰剂，血管手术前治疗时间中值37天。
Results: a total of 250 patients were assigned to fluvastatin, and 247 to placebo, a median of 37 days before vascular surgery.
以上提示，氟伐他汀能有效抑制血管内膜过度增生，可能与其抑制平滑肌细胞增殖并可促进细胞凋亡有关。
Conclusion Fluvastatin inhibit excessive thickening of vascular intima effectively, which may partly be related to its inhibiting the proliferation of VSMCs and promoting the apoptosis of cells.
结论氟伐他汀可逆转糖尿病大鼠心肌间质纤维化并改善心功能，这种作用可能与其抑制CTGF的表达有关。
CONCLUSION Fluvastatin could inhibit myocardial interstitial fibrosis and improve the cardiac function of diabetic rats, which might be related to the down-regulating of the CTGF expression.
结论氟伐他汀可逆转糖尿病大鼠心肌间质纤维化并改善心功能，这种作用可能与其抑制CTGF的表达有关。
CONCLUSION Fluvastatin could inhibit myocardial interstitial fibrosis and improve the cardiac function of diabetic rats, which might be related to the down-regulating of the CTGF expression.
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