方法应用免疫组织化学染色技术,以正常皮肤和正常瘢痕作对照,观察了瘢痕疙瘩和增殖性瘢痕中vegf和PCNA的表达。
Method With immunohistochemistry technique, the expression of VEGF and PCNA in keloids and hypertrophic scars was investigated, and the normal skins and scars were taken as controls.
而在成熟稳定的增生性瘢痕中,两种蛋白表达有所下降,但仍高于正常皮肤组织。
In mature hypertrophic scar, the expression of these proteins decreased but was still higher than that of normal skin.
目的观察正常的黑色素细胞对增生性瘢痕成纤维细胞的生物学效应。
AIM To observe the effects produced by melanocytes on the proliferation of hypertrophic scar fibroblasts.
结果p-ERK和PCNA蛋白在病理性瘢痕中与非病理瘢痕、正常皮肤差异有显著性(P<0.05)。相关性分析有显著性(P<0.05)。
Results The expression of PCNA and pERK were significant difference between pathologic scars group and the two control groups (P<0.05), correlativity analysis showed significant difference (P<0.05).
心肌梗死之后,梗死后形成的瘢痕组织,会在心脏内形成不规则形状的切片,它将阻断正常电活动或者引起短路。
Following a heart attack, irregularly shaped sections of dead scar tissue may form in the heart and block the electrical flow or cause a short circuit.
结果发现瘢痕疙瘩和结缔组织样品中有氧自由基存在,而正常皮肤组织内则未能检测到。
The results showed that more oxygen free radicals were identified in keloid, less in normal connective tissue while no free radicals were found in skin.
方法:瘢痕疙瘩和正常皮肤(作为阴性对照)均来自北京大学第三医院成形科手术患者各6例。
METHODS: Keloids and normal skins(negative controls) were obtained from 6 patients and 6 normal people who operated in the Department of Plastic Surgery, Peking University Third Hospital.
方法:取瘢痕疙瘩和正常皮肤,采用组织块培养法进行成纤维细胞体外培养。
METHODS: Keloid and norm al skin tissue were collected for the fibroblasts in vitro using tissue-block cultivation.
结果:瘢痕组织中细胞凋亡的数目与正常组织明显不同。
RESULTS: There existed evident difference in apoptotic cells in the dermis between scars tissue and normal human skin.
结果:60例患者,经过2至4周治疗,有效率达100%,皮肤瘢痕轻微,功能结构基本正常,预后良好。
Results: All the 60 cases were cured with normal skin structure and function, good prognosis and only slight scar left after 2-4 weeks' treatment.
结论:几丁糖对正常皮肤及增生性瘢痕和瘢痕疙瘩来源的成纤维细胞的生长增殖均有抑制作用,有望在瘢痕的防治中发挥重要作用。
Conclusion Chitosan can inhibit the growth, proliferation of fibroblasts derived from keloid, hypertrophic scars and normal skin, and may play important role in the prevention and treatment of scars.
左侧为相对正常的右肾,仅有少量散在的浅的皮质瘢痕,肾上极有大的黄褐色瘢痕。
There is a relatively normal kidney at the left with only a few scattered, shallow cortical scars and one fairly large pale tan-yellow scar in the upper pole.
瘢痕组织排泄对比剂较慢,因此即使血流和正常组织对比剂的排泄后,瘢痕组织信号仍较高。
Scar tissue is slow to give up this contrast agent and its signal is therefore retained despite a washing out of contrast from the blood stream and normal tissues.
结论对于面颊部瘢痕在颈侧皮肤正常的情况下应首选扩张术。
Conclusion The expansion is a best choice for defect of cheek when lateral neck skin is normal.
目的比较正常和病理增生性瘢痕皮肤成纤维细胞对细胞因子、细胞外间质和胶原基因启动子的不同反应性。
Objective to compare the different response of dermal fibroblasts from normal and scar-ring skin to cytokines, extracellular matrix and collagen promoter.
本综述的目的就是研究瘢痕疙瘩在分子和细胞水平上和正常创伤愈合过程的关系的病原生物学。
The aim of this review was to investigate the molecular and cellular pathobiology of keloid disease in relation to the normal wound healing process.
方法:采用免疫组织化学方法检测40例病理性瘢痕组织、20非病理性瘢痕组织和20例正常皮肤组织中igf - 1r、PTEN、PCNA的表达情况。
Methods: The expression of IGF-1R, PTEN, and PCNA in 40 pathologic scars, 20 non-pathologic scars, and 20 samples of normal skin tissue were detected using immunohistochemical methods.
方法:采用免疫组织化学方法检测40例病理性瘢痕组织、20非病理性瘢痕组织和20例正常皮肤组织中igf - 1r、PTEN、PCNA的表达情况。
Methods: The expression of IGF-1R, PTEN, and PCNA in 40 pathologic scars, 20 non-pathologic scars, and 20 samples of normal skin tissue were detected using immunohistochemical methods.
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