• 方法应用免疫组织化学染色技术正常皮肤正常瘢痕作对照,观察瘢痕疙瘩和增殖性瘢痕vegfPCNA表达

    Method With immunohistochemistry technique, the expression of VEGF and PCNA in keloids and hypertrophic scars was investigated, and the normal skins and scars were taken as controls.

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  • 而在成熟稳定的增生性瘢痕中,两蛋白表达有所下降高于正常皮肤组织

    In mature hypertrophic scar, the expression of these proteins decreased but was still higher than that of normal skin.

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  • 目的观察正常黑色素细胞生性瘢痕成纤维细胞生物学效应。

    AIM To observe the effects produced by melanocytes on the proliferation of hypertrophic scar fibroblasts.

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  • 结果p-ERKPCNA蛋白在病理性瘢痕中与非病理瘢痕正常皮肤差异显著性(P<0.05)。相关性分析显著性(P<0.05)。

    Results The expression of PCNA and pERK were significant difference between pathologic scars group and the two control groups (P<0.05), correlativity analysis showed significant difference (P<0.05).

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  • 心肌梗死之后,梗死后形成瘢痕组织心脏内形成不规则形状的切片,它将阻断正常电活动或者引起短路

    Following a heart attack, irregularly shaped sections of dead scar tissue may form in the heart and block the electrical flow or cause a short circuit.

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  • 结果发现瘢痕疙瘩和结缔组织样品有氧自由基存在,正常皮肤组织内则未能检测到。

    The results showed that more oxygen free radicals were identified in keloid, less in normal connective tissue while no free radicals were found in skin.

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  • 方法瘢痕疙瘩正常皮肤(作为阴性对照来自北京大学第三医院成形手术患者各6例。

    METHODS: Keloids and normal skins(negative controls) were obtained from 6 patients and 6 normal people who operated in the Department of Plastic Surgery, Peking University Third Hospital.

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  • 方法瘢痕疙瘩正常皮肤采用组织块培养法进行纤维细胞体外培养

    METHODS: Keloid and norm al skin tissue were collected for the fibroblasts in vitro using tissue-block cultivation.

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  • 结果瘢痕组织细胞凋亡的数目正常组织明显不同

    RESULTS: There existed evident difference in apoptotic cells in the dermis between scars tissue and normal human skin.

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  • 结果60患者,经过2至4治疗,有效率达100%,皮肤瘢痕轻微功能结构基本正常预后良好

    Results: All the 60 cases were cured with normal skin structure and function, good prognosis and only slight scar left after 2-4 weeks' treatment.

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  • 结论:几正常皮肤生性瘢痕瘢痕疙瘩来源纤维细胞生长增殖均有抑制作用,有望瘢痕防治发挥重要作用

    Conclusion Chitosan can inhibit the growth, proliferation of fibroblasts derived from keloid, hypertrophic scars and normal skin, and may play important role in the prevention and treatment of scars.

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  • 左侧相对正常的右仅有少量皮质瘢痕,肾黄褐色瘢痕

    There is a relatively normal kidney at the left with only a few scattered, shallow cortical scars and one fairly large pale tan-yellow scar in the upper pole.

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  • 瘢痕组织排泄对比慢,因此即使血流正常组织对比剂排泄后,瘢痕组织信号仍较高。

    Scar tissue is slow to give up this contrast agent and its signal is therefore retained despite a washing out of contrast from the blood stream and normal tissues.

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  • 结论对于面颊部瘢痕颈侧皮肤正常情况下应首选扩张术。

    Conclusion The expansion is a best choice for defect of cheek when lateral neck skin is normal.

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  • 目的比较正常病理增生性瘢痕皮肤成纤维细胞细胞因子细胞外间质胶原基因启动子不同反应性。

    Objective to compare the different response of dermal fibroblasts from normal and scar-ring skin to cytokines, extracellular matrix and collagen promoter.

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  • 综述目的就是研究瘢痕疙瘩分子细胞水平上和正常创伤愈合过程关系的病原生物学。

    The aim of this review was to investigate the molecular and cellular pathobiology of keloid disease in relation to the normal wound healing process.

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  • 方法采用免疫组织化学方法检测40病理性瘢痕组织、20非病理性瘢痕组织20例正常皮肤组织igf - 1rPTENPCNA表达情况。

    Methods: The expression of IGF-1R, PTEN, and PCNA in 40 pathologic scars, 20 non-pathologic scars, and 20 samples of normal skin tissue were detected using immunohistochemical methods.

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  • 方法采用免疫组织化学方法检测40病理性瘢痕组织、20非病理性瘢痕组织20例正常皮肤组织igf - 1rPTENPCNA表达情况。

    Methods: The expression of IGF-1R, PTEN, and PCNA in 40 pathologic scars, 20 non-pathologic scars, and 20 samples of normal skin tissue were detected using immunohistochemical methods.

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