本发明涉及一种具有正常核型的培养的动物体细胞;
The present invention relates to a cultured animal body cell with normal nuclear type.
背景:目前在胚胎多潜能干细胞建系和培养过程中,存在着建系率低、具有正常核型的干细胞系比率低等问题。
BACKGROUND: Presently, some problems still exists during establishment and culture of embryo multipotential stem cells, such as low rate of establishment, low rate of stem cells with normal karyotype.
方法:采用G、C显带染色体核型分析等方法,比较染色体异态核型人群和正常核型人群的早期生殖障碍的发生率。
Methods: The incidence rates of early reproduction inability of chromosome heteromorphism group and normal karyotype group were compared by using G, C-banded chromosome karyotype analysis.
本研究将染色体多态核型人群和正常核型人群分组,进行G显带染色体核型分析,以比较两组人群的生殖异常的发生率。
The incidence rates of reproduction abnormality of chromosome polymorphism group and normal karyotype group have been compared by G-banded chromosome karyotype analysis.
羊水诊断核型正常(46,xx)。
结果64%的卵细胞核型正常,36%的卵细胞为非整倍体,其中22%为同源染色体不分离,14%为姐妹染色单体非平衡性过早分离。
Results 64% of oocytes were normal, 36% of oocytes were aneuploidy, of which 22% were due to nondisjunction and 14% unbalanced predivision.
父母的行为与其胎儿染色体核型正常或异常关系不大。
Parents' behaviour had little correlation with fetus chromosome abnormalities.
所有患者染色体核型均正常,未见染色体核型缺失及多倍体,均为46xy或46xx型。
The karyotype of their chromosomes were normal (46xy or 46xx), no chromosome aberration, chromosome loss and polyploid.
核型异常者进展为白血病的危险性明显高于核型正常者。
The risk of leukemic transformation was higher in cases with abnormal karyotypes than with normal karyotypes.
结果对照组性染色体核型均正常,难免流产组性染色体核型异常2例,但两组的差异无显著性;
Results Nuclear types of normal villous tissues were all normal. There were 2 cases with abnormal nuclear types in inevitable abortion group, but the difference was not significant.
目的观察正常细胞核型中含有极少量21 -三体细胞的患儿临床表型及发育损害的相关关系。
Objective: a few trisomy 21 cells in normal chromosome karyotype was been observed for study of the correlation of clinical phenotype and development damage in sick children of Down's syndrome.
核型分析结果显示,ZP - 1细胞为正常女性染色体结构。
Karyotype analysis showed that ZP-1 cells have a normal female chromosome structure.
核型分析结果显示,ZP - 1细胞为正常女性染色体结构。
Karyotype analysis showed that ZP-1 cells have a normal female chromosome structure.
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