同源框基因是一类控制胚胎发育和细胞分化的调节基因。
Homeobox gene is a sort of regulatory gene which controls embryonic development and cellular differentiation.
证明这些想法的唯一途径就是用这些基因人工构建一个的染色体,而且我们必须用基于表达框的方式来达到这一目的。
The only way to prove these ideas was to construct an artificial chromosome with those genes in them, and we had to do this in a cassette-based fashion.
之后,这些小的反义RNA可能会在RNA拼接中发挥作用,如在选择压力下修复基因组中一个区域,抑或在丧失或损坏一个模块后恢复一个读码框。
Such small antisense RNAs may later have gained a role in RNA editing, possibly under selective pressure to repair a region or restore a reading frame after loss or erosion of a module.
链霉菌基因组中常见连续两个基因重叠的现象(如ATGA),这为基因的同框敲除或取代研究带来很大困扰。
The gene overlapping(ATGA) is widespread in streptomycetes, making it difficult to perform in-frame deletion or replacement for functional analysis of target genes.
结论:敲除叉头框c 2基因可使小鼠室间隔发育缺损。
Conclusion Targeting mutation of Fox C2 gene can result in ventricular septal defect.
COX3基因编码框包含789个核苷酸,编码262个氨基酸的蛋白质。
The open reading frame of COX3 gene contains 789 nucleotides, encoding a putative protein of 262 amino acids.
大肠杆菌启动子能起始基因的转录,它主要由两段比较保守的序列片断- 10框、- 35框和它们之间一段长度可变的碱基序列组成。
Escherichia coli promoter, which could initiate transcription of a gene, was mainly consisted of two conserved sequences, -10 box and -35 box, and spacer between them, whose length is changeable.
副黏病毒的V蛋白是结构蛋白P基因内使用不同的阅读框编码产生的一种非结构蛋白,具有抗干扰素(IFN)的作用。
V proteins are non-structural proteins of paramyxovirus that are generated due to the use of different open reading frame within P gene and are responsible for interferon(IFN)resistance.
方法:通过敲除小鼠叉头框c 2基因,解析敲除叉头框c 2基因小鼠的心脏发育情况。
Methods Fox C2 deficient mice were reproduced by targeting mutation and the developmental anomaly in heart was analyzed.
报道一个用于基因序列分析的微机程序,应用它可方便地完成:①按三种读框将DNA序列翻译成相应的氨基酸序列;
Microcomputer programs for gene analysis have been established, which can dealth with the following. 1)translating a DNA sequence into an amino acid sequence in three frames;
鹅细小病毒基因组含有两个主要开放性阅读框(ORF),分别编码非结构蛋白和结构蛋白。
The genomes of GPV contain two main open reading frame (ORF), encoding structural proteins and non-structural proteins. VP3 protein is a mainly structural proteins and highly conservative.
据估计,原核和真核细胞基因组中大约有20- 30%的阅读框编码膜蛋白,凸显膜蛋白研究的重要性。
It was estimated that 20-30% of the open reading frames in both prokaryotic and eukaryotic genomes encode membrane proteins, underscoring the importance of membrane protein research.
据估计,原核和真核细胞基因组中大约有20- 30%的阅读框编码膜蛋白,凸显膜蛋白研究的重要性。
It was estimated that 20-30% of the open reading frames in both prokaryotic and eukaryotic genomes encode membrane proteins, underscoring the importance of membrane protein research.
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