此外，活性增强的核转录因子- kB未被逆转。
Additionally, increased activity of nuclear factor-kB was not reversed.
目前对这一现象有四种解释：ROS活化核转录因子KB并诱导核转录因子-KB表达，导致细胞凋亡；
At present, the explanations for this phenomenon are: 1) ROS activated nuclear factor-KB and induction of the expression of nuclear factor-KB; 2) mitochondria-mediated cell apoptosis;
低氧诱导因子1 (HIF - 1)是重要的氧依赖性核转录因子，低氧条件下能上调多个靶基因表达以减少缺氧性损伤。
Hypoxia inducible factor-1 (HIF-1) is a key oxygen-dependent transcription factor that up-regulates many protective genes against hypoxia-induced injury.
核受体可单独或相互联系而发挥作用，亦可与其他转录因子进行交互通话。
Nuclear receptors can act alone or interact on each other, and they can also crosstalk with other transcriptional factors.
PPAR激动剂，是细胞核激素受体家族转录因子的一个成员，被广泛用来治疗II型糖尿病，而且相对无毒。
Agonists of PPAR, a member of the nuclear hormone receptor family of transcription factors, are widely used in the treatment of type II diabetes and are relatively non-toxic.
目的克隆激活转录因子(atf)5，构建其真核表达载体，观察其在细胞中的表达定位。
Objective to clone the gene activating transcription factor 5 (ATF5), construct the expression plasmid and detect the localization of ATF5 in cultivated cells.
BRD7被鉴定为一个鼻咽癌密切相关新基因和潜在的核转录调节因子。
BRD7 was identified as a novel gene tightly associated to nasopharyngeal carcinoma (NPC) and also a nuclear transcriptional regulatory factor.
EIN3基因首先是从拟南芥的突变体中克隆得到的，作用于CTR下游，位于核内，编码转录因子。
EIN3 was first cloned in Arabidopsis thalina mutant, and it has been suggested that EIN3 acted downstream to CTR located in nuclear and encoded transcription factors.
核受体是配体活化的转录因子，能调控大量的靶基因。
Nuclear receptors (NRs) are ligand-activated transcription factors that regulate the activation of a variety of important target genes.
CREB是细胞核内的转录因子，能显著提高细胞内其他蛋白质的含量，据研究认为CREB不论是在海参还是在人体中，均与生物有机体中记忆的形成有关。
CREB, a transcription factor that typically increases the production of other proteins in cells, is believed to be involved in memory formation in organisms from sea slugs to humans.
公路隧道暴露组的支气管上皮细胞比对照组具有更高的转录因子组分c - Jun的核表达。
Significantly higher nuclear expression of the transcription factor component c-Jun was found in the bronchial epithelium after exposure.
因此，孤立性纤维性肿瘤中可见细胞核表达胞浆转录因子STAT6，并且是该疾病的一个有用诊断指标。
As a result, nuclear expression of the cytoplasmic transcription factor STAT6 is found in solitary fibrous tumor and serves as a useful diagnostic marker.
提示面神经损伤后面神经核运动神经元内由信号转导子和转录激活子3介导的细胞因子的信号转导作用增加。
Action of signal transduction of mediated cytokine indicated by STAT3 raises in motoneurons of facial nerve nucleus after facial nerve injury.
其中M区高度保守，它编码真核生物转录因子的DNA结合域，具有DNA结合和二聚体形成的作用。
The M domain, which encodes the DNA-binding domain and plays the roles of both binding DNA and forming dimmers, is the most conserved region.
其中M区高度保守，它编码真核生物转录因子的DNA结合域，具有DNA结合和二聚体形成的作用。
The M domain, which encodes the DNA-binding sequence and plays the roles of both binding DNA and forming dimmers, is the most conserved region.
大多数雄激素非依赖性前列腺癌均高表达AR和核受体辅活化子、如转录中间因子2（TIF-2），ARA24、PIAS、类固醇受体辅活化子-1（SRC-1）等有力地支持了这个假说。
The "superactive AR"hypothesis was supported by the fact that the majority of AIPC expresses high level of AR and nuclear receptor(NR) coactivators, such as TIF-2, ARA24, PIAS, SRC-1.
真核生物中热激蛋白基因的表达受热激转录因子的调节。
The expression of heat shock protein genes in eukaryotes is regulated by heat shock transcription factor (HSF).
拟南芥WRKY2蛋白定位于细胞核， 表明WRKY2 是转录调控因子。
The fact that Arabidopsis WRKY2 protein was nuclear-localized supported that WRKY2 functioned as a transcription factor.
然而，质体仅具有半自主性转录和翻译机制，其内源基因的转录要依赖于核基因编码的转录因子。
However, plastids only have a semi-autonomous transcription and translation machinery. The transcription of endogenous plastid genes is largely dependent on nuclear-encoded transcription factors.
锌指蛋白是一类广泛存在于原核和真核生物体中的重要转录调控因子，在动植物的生长发育过程中均起着重要作用。
The family of zinc finger proteins is an important member of transcription factors which exists widely in prokaryote and eukaryote.
细胞核中，抑制素通过与转录因子如rb和p 53相互作用来调节靶基因的转录(2,5)。
In the nucleus prohibitins interact with transcription factors such as Rb and p53 to regulate target gene transcription (2, 5).
细胞核中，抑制素通过与转录因子如rb和p 53相互作用来调节靶基因的转录(2,5)。
In the nucleus prohibitins interact with transcription factors such as Rb and p53 to regulate target gene transcription (2, 5).
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