多项研究表明,4 -氧代二氢喹啉类有良好的口服利用率及中等程度的血浆清除率,不仅对核苷酸聚合酶产生抑制,还可以抑制细胞内的病毒复制。
Many studies show that 4-oxo-dihydroquinolines have good oral bioavailability and plasma clearance, and they suppress both the DNA polymerase of HSV and virus replication in the cells.
二脱氧核苷酸是DNA聚合酶的链延长抑制剂。
Dideoxynucleotide is chain-elongating inhibitor of DNA polymerase.
当聚合酶将一个核苷酸加在新互补链的起始引子之后,或接合酶认定某段核苷酸链与原始模版配对,就可利用这些反应来得出原始模版的序列。
As bases are added by polymerase to the starting point of a new complementary strand, known as a primer, or recognized by ligase as a match, the template's sequence is revealed.
本发明进一步提供用作分子探针或聚合酶链式反应(PCR)扩增引物的核酸分子,即合成的或天然的寡聚核苷酸。
The present invention further provides nucleic acid molecules for use as molecular probes, or as primers for polymerase chain reaction (PCR) amplification, i. e. synthetic or natural oligonucleotides.
但是研究人员不清楚的是聚合酶是怎样避免把构成DNA链的NTP添加到RNA链上的,毕竟脱氧核核苷酸和核糖核苷酸只是相差一个氧原子。
And the scientists didn't know either how the polymerase avoids substituting the NTPs that constitute DNA for the correct RNA building blocks, molecules that differ by only one oxygen atom.
但是研究人员不清楚的是聚合酶是怎样避免把构成DNA链的NTP添加到RNA链上的,毕竟脱氧核核苷酸和核糖核苷酸只是相差一个氧原子。
And the scientists didn't know either how the polymerase avoids substituting the NTPs that constitute DNA for the correct RNA building blocks, molecules that differ by only one oxygen atom.
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