“这给了真核生物基因原料,使它们能够积累新的基因。从规模上来讲,重大基因家族和调节系统对于细菌来讲是完全无法负担的”莱恩博士说。
"This gives eukaryotes the genetic raw material that enables them to accumulate new genes, big gene families and regulatory systems on a scale that is totally unaffordable to bacteria," said Dr Lane.
PPAR激动剂,是细胞核激素受体家族转录因子的一个成员,被广泛用来治疗II型糖尿病,而且相对无毒。
Agonists of PPAR, a member of the nuclear hormone receptor family of transcription factors, are widely used in the treatment of type II diabetes and are relatively non-toxic.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上,从而在转录水平上调节基因的表达。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
属于核受体超家族成员,是一个孤儿受体。
GCNF (Germ Cell nuclear Factor) is a member of nuclear receptor superfamily and also an orphan receptor.
YEATS结构域蛋白家族成员存在于从酵母到人类超过70种真核生物中。
The YEATS domain family of members, conserved from yeast to human more than 70 eukaryotic species.
法尼酯x受体(FXR)是代谢性核受体超家族中的一员,在调节胆汁及脂类等物质代谢、维持内环境的稳定方面发挥着重要作用。
Farnesoid X receptor (FXR), a member of the metabolic nuclear receptor superfamily, plays key roles in maintaining bile acid and lipid homeostasis.
法尼酯x受体(FXR)是代谢性核受体超家族中的一员,在调节胆汁及脂类等物质代谢、维持内环境的稳定方面发挥着重要作用。
Farnesoid X receptor (FXR), a member of the metabolic nuclear receptor superfamily, plays key roles in maintaining bile acid and lipid homeostasis.
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