NBT还原实验发现部分早幼粒白血病细胞胞奖内出现紫蓝色颗粒,并见到核碎解成染色质小体(凋亡小体)。
Part of the acute promyelocytic leukemia cells appeared indigo granules and apoptosis body in plasma through NBT test.
核小体是染色质的基本单位。
研究人员怀着了解两种不同的甲基化标记怎样影响核小体和染色质结构的目的开始工作。
The researchers began their work with the goal of learning how two different methylation marks affect the overall structure of nucleosomes and chromatin.
核小体串珠压缩整合而成的一种纤维结构,形成染色质结构的功能单位。
Solenoid --- A fiber composed of compacted strings of nucleosomes, forming the fundamental unit of chromatin organization.
核心过程的表观遗传的产业包括DNA甲基化、组蛋白改性、核小体重建、核染色质动力学和互动子都存在。
Core processes of epigenetic inheritance include DNA methylation, histone modification, nucleosome remodeling, nuclear dynamics and chromatin interaction with non-coding RNAs.
但是有趣的问题是它们是否随着甲基化发生动态变化——个体核小体是否有会有更大的倾向来解开,拆开染色质,还是仅仅被改型。
But the interesting question will be whether their dynamics change with methylation-whether individual nucleosomes may have a higher propensity to unfold, to unravel slightly or just to be remodeled.
AD脑组织易损区存在着DNA断裂损伤,凋亡小体,染色质凝集及凋亡相关的基因表达改变。
There existed DNA breakage, apoptotic body, chromosome aggregation and the changes of related apoptotic gene expression in the AD brain.
对于不同状态的染色质,核小体中会组装入相应的组蛋白变体,并且各种组蛋白变体的尾部也能发生多种修饰。
To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants tails.
对于不同状态的染色质,核小体中会组装入相应的组蛋白变体,并且各种组蛋白变体的尾部也能发生多种修饰。
To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants' tails.
利用这种新型工具,Luger和他的同事进行了X射线晶体学和生物物理学研究,来看甲基化怎样影响染色质和核小体结构。
With this new set of tools, Luger and her colleagues did X-ray crystallographic and biophysical studies to see how methylation affects the structure of chromatin and nucleosomes.
Luger和他的同事随即包装了从Shokat小组得来的修饰过的组蛋白,形成核小体和染色质的重组体。
Luger and her colleagues next packaged the modified histones they received from Shokat's group into recombinant nucleosomes and chromatin.
视野中心部分的RBC含有几个Howell - Jolly小体或残余的核染色质内容物。
The RBC in the center of the field contains several Howell-Jolly bodies, or inclusions of nuclear chromatin remnants.
用这个技术,总的染色质首先被切成单个核小体大小的片断。
With this technique, total chromatin is first cut into single nucleosome-sized pieces.
光学显微镜下可明显看到形成的凋亡小体,经DAPI染色可以看到染色质凝集和碎裂。
Optical microscope observation demonstrated the formation of apoptotic bodies and the condensation of nuclear chromatin after DAPI staining.
真核细胞中,核小体是染色质的基本单位,它由两个拷贝HA、HB、H和H所组成的核心组蛋白八聚体,及缠绕于其上的bpDNA构成。
In eukaryotic cells, the fundamental unit of chromatin is nucleosome, which is composed of a histone octamer with two copies of HA, HB, H and H and base pairs of DNA.
真核细胞中,核小体是染色质的基本单位,它由两个拷贝HA、HB、H和H所组成的核心组蛋白八聚体,及缠绕于其上的bpDNA构成。
In eukaryotic cells, the fundamental unit of chromatin is nucleosome, which is composed of a histone octamer with two copies of HA, HB, H and H and base pairs of DNA.
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