结论硫芥能直接诱发细胞染色体损伤。
Conclusion Sulfur mustard can directly induce chromosome damage.
对照射后蚕豆根尖下细胞中的染色体损伤情况进行了研究。
Studied on chromosome damage in cells of broad bean root tip.
微核技术作为染色体损伤的快速检测方法，近年来获得广泛的应用。
Recently years, micronucleus technology has been widely used as a method for rapidly detecting the damage of chromosome.
结论汽车尾气可导致机体氧化与抗氧化系统平衡紊乱；并能引起细胞染色体损伤。
Conclusion Automobile exhausts could break the balance between oxidative system and anti oxidative system and damage chromosomes of cells.
结果表明：DCAP是一种染色体损伤剂，诱发的畸变主要为染色单体断裂和交换；
Results showed that DCAP was clastogen and the aberrations were mainly chromatid breaks and exchanges.
我们初步认为，TFD对X线诱发的染色体损伤可能具有修复功能，并对其修复的可能机理予以初探。
We suggested that TFD could repair the chromosome damage induced by X-irradiation, and discussed the repairing mechanism.
应用小鼠骨髓微核试验及小鼠睾丸染色体畸变试验，测试蜂胶对诱变剂诱发的染色体损伤的保护作用。
Micronucleus test of bone marrow cells and chromosome aberration test were performed in mice to assess the antagonistic effect of propolis to mutation induced by mutagens.
近来的证据显示：自噬提供了一个保护性功能来限制肿瘤坏死和炎症，同时减轻了肿瘤细胞内的染色体损伤来回应代谢性应激。
Recent evidence suggests that autophagy provides a protective function to limit tumour necrosis and inflammation and to mitigate genome damage in tumour cells in response to metabolic stress.
染色体组包涵很多基因，太多的错误复制，损伤和遗漏会导致数以万计的基因改变。
Chromosomes contain many genes, so mis-copies, breaks and omissions lead to tens of thousands of genetic changes.
癌细胞可以无限制的复制而不经受染色体的损伤因为它们可以保持它们的端粒。
Cancer cells have the ability to keep on dividing without suffering chromosome damage because they preserve their telomeres.
伴随DNA改变的基因损伤会导致基因的点突变、染色体间基因移位和扩增性基因复制。
Genetic damage with DNA alterations leads to point mutations of genes, translocations of genetic material between chromosomes, and gene reduplication with amplification.
结论：铅可引起人体染色体的损伤。
目的探讨X射线工作人员染色体畸变与血象变化的关系，为辐射损伤机制提供线索。
Objective To explore the correlation of chromosome aberration and the hemogram variation in X-ray workers and provide the mechanism index for radiation damage.
多种细胞机制功能障碍将导致染色体不稳定性，包括染色体分离、DNA损伤反应、细胞周期检查点、端粒功能等。
Several factors, such as defects in chromosome segregation and DNA damage response, failure of cell cycle checkpoint, telomere dysfunction, may cause chromosomal instability.
目的：观察氟、砷单独及联合作用对正常人淋巴细胞染色体的损伤作用及特点。
Objective: Our objective of this study is to observe the features of chromosome damage induced by arsenic, fluoride and their combination in cultured human lymphocytes.
目的与方法：单细胞凝胶电泳技术(SCGE)、姐妹染色单体交换法(SCE)和染色体畸变分析法均能被用来检测dna的损伤或修复。
Purpose and methods: Single cell gel electrophoresis (SCGE), sister chromatid exchanges (SCE), chromosome aberrations are three methods to determine DNA damage and repair.
此外，为了充分确定新细胞含有与双亲细胞完全一样的信息，任何对涉及到几个染色体的DNA损伤都必须被修复。
Moreover, to fully ascertain that the new cells will contain the same genetic information as the parental cells, any damage to the DNA, which is organised into several chromosomes, must be repaired.
这方面研究主要包括克隆细胞存活、细胞染色体畸变和细胞DNA损伤等。
These researches mainly include:clonogenic cell survival, chromosome damages and double-strand breaks of DNA.
第三部分，采用彗星试验、微核试验和染色体畸变试验检测和评估职业接触铅人群的遗传损伤效应。
Finally, comet assay, micronucleus and chromosomal aberration test were used to study and estimate the genetic damage effect of lead on occupational exposure workers.
结论原发性高血压是由DNA损伤引起的人类表型缺陷，该病症符合常染色体显性遗传，具延迟外显性。
Conclusion: the essential hypertension is the human phenotype blemish caused by injured DNA. It is compatible with an autosomal dominant inheritance and its performance is delayed.
来自AT病人的细胞显示有缺陷的DNA损伤诱导检验点激活，对放射的敏感性和频率较高的染色体断裂(3,4)。
Cells from at patients display defective DNA damage-induced checkpoint activation, sensitivity to radiation, and a higher frequency of chromosome breakage (3, 4).
结论饥饿状态可造成大白鼠海马细胞染色体dna损伤及部分细胞死亡。
Conclusions Food hunger lead to nuclear DNA damage and death of hippocampal cells in rats.
利用蚕豆根尖微核技术研究农药乙蒜素和细菌溴腈对蚕豆根尖细胞的遗传损伤，测定蚕豆根尖细胞的微核率、有丝分裂指数和染色体畸变率。
With different concentrations of sewage and aluminum sulfate as a mutagen, pea root tip cells in the mitotic index, micro-rate and the rate of chromosomal aberrations are determined.
虽然对染色体上断裂点多发部位的真正生物学意义尚不清楚，但可以肯定的是有关损伤热点的研究是辐射远后效应研究中十分重要的一部分。
Although the true biological significance of break point regions has been not clear, there is no doubt that research on hot damage point is important part of study on after effect of radiation.
细胞化学分析证明，受激光照射的染色体区段的DNA遭到了损伤。
Cytochemical analysis demonstrated that chromosomal DNA at the specific irradiated region was impaired.
本文主要对辐射诱发染色体畸变和微核的形成与细胞分裂周期的关系作了综述和分析，并对微核细胞率作为辐射损伤的细胞学指标进行了评价。
This paper reviewed the relationship between chromosomal aberrations at the different stages of mitotic cycle and the mechanism of chromosomal aberrations and micronuclei induced by radiation.
本文主要对辐射诱发染色体畸变和微核的形成与细胞分裂周期的关系作了综述和分析，并对微核细胞率作为辐射损伤的细胞学指标进行了评价。
This paper reviewed the relationship between chromosomal aberrations at the different stages of mitotic cycle and the mechanism of chromosomal aberrations and micronuclei induced by radiation.
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