染色体分离是真核生物正确传递遗传信息的关键。
The faithful chromosome segregation is crucial for transmitting the genetic information accurately in eukaryotic organisms.
目的:研究BUB1基因表达调控对染色体分离的影响。
Objective:To investigate the effect of BUB1 expression in embryonic cells on chromosome segregation.
它与同源染色体联会、遗传交换、染色体分离密切相关。
The structure is closely related with homologous chromosomes synapsis, recombination and segregation.
研究小组发现了一些对DNA包装,染色体分离和富集至关重要的蛋白。
The team found some were vital for DNA packaging, chromosome segregation and fertility.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能,例如基因表达和染色体分离等。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
准确的染色体分离依赖于有丝分裂过程的精确调控,包括有丝分裂的时间,及纺锤体检查点的正确调控等。
Accurate chromosome segregation depends on the precise regulation of mitotic progression, including the timing of mitosis and proper regulation of spindle assembly checkpoint.
多种细胞机制功能障碍将导致染色体不稳定性,包括染色体分离、DNA损伤反应、细胞周期检查点、端粒功能等。
Several factors, such as defects in chromosome segregation and DNA damage response, failure of cell cycle checkpoint, telomere dysfunction, may cause chromosomal instability.
细胞用来分离染色体的精细机器,是由成千上万被称为微管的微型管状组织组装而成的。
Hundreds of tiny tube-like structures, called microtubules, make up the machinery that cells use to separate the chromosomes.
因此当互补染色体丢失时,就会产生恶性分离子。
Malignant segregants may, therefore, arise when complementing chromosomes are lost .
研究目的遗传的不稳定性是肿瘤生成的最重要的因素之一,而染色体的精确分离是基因物质稳定遗传关键。
Objective genetic instability is one of the most important factors to underlie neoplasia, and precise segregation of the chromosome is critical for stable inheritance of genetic material.
利用抗病分离群体,我们在野生二粒小麦2B染色体上发现了多个抗白粉病基因,并利用SSR分子标记进行了定位。
Several powdery mildew resistance genes derived from wild emmer accessions have been mapped on the short and long arms of chromosome 2B by SSR marker.
人工酵母染色体(YAC)技术是人类基因组分析及疾病相关基因的分离、克隆中的关键技术。
Yeast Artificial Chromosome (YAC) techniques play an important role in the analysis of human genome and the isolation and cloning of disease related genes.
研究表明,TBZ可能通过抑制微管蛋白聚合来影响染色体正常分离,诱发非整倍体。
The result suggested that TBZ may induce aneuploidy by the pathway of tubulin polymerization inhibition which is able to lead to chromosomal malsegregation.
双线期时,配对的染色单体开始从四分体中分离,此时常可见染色体交叉。
In diplotene the pairs of chromatids begin to separate from the tetrad formed by the association of homologous chromosomes.
结论外源基因(人组织蛋白酶k基因)已经整合到小鼠的染色体上,并且按孟德尔遗传定律中的分离定律进行遗传。
Conclusion the foreign gene (human Cathepsin K gene) has already integrated into mouse chromosome, and it can inherit in accordance with Mendelian inheritance.
修改后的细菌染色体再从酵母中分离,进而移植入山羊支原体,一个与原细菌亲缘的菌种中,最终创造出新型的丝状支原体细胞。
This modified bacterial chromosome was then isolated from yeast and transplanted into a related species of bacteria, Mycoplasma capricolum, to create a new type of M. mycoides cell.
在终变期配对的同源染色体中的姐妹染色单体完成分离,染色体变成紧密凝集的状态,缩至最小长度。
During diakinesis the sister chromatids of homologous pairs of chromosomes complete their separation and the chromosomes coil tightly shortening and thickening.
广泛性焦虑校正分离率为0.225,与常染色体隐性遗传的分离率0.25相比较,差异无显著性(P>0.05);
The segregative rate in generalized anxiety disorder was 0.225, which was not significantly different (P>0.05) from the segregation rate 0.25 in autosome recessive inheritance.
因此当互补染色体丢失时,就会产生恶性分离子。
Maligrant segregants may, therefore, arise when complementing chromosomes are lost.
如果这些染色体复制过程的自然结果所造成的纠结没有被解开,染色体就不能被分离并送到两个子细胞中。
If these tangles, which are a natural consequence of the DNA copying process, are left unresolved the chromosomes cannot be separated and sent to the two nascent daughter cells.
特别地,研究人员发现TEX11可以在减数分裂的染色体上形成分离中心(discrete foci),这似乎是一种新的减数分裂重组机制的一部分。
Specifically, researchers found that TEX11 forms discrete foci on meiotic chromosomes and appears to be a novel constituent of the meiotic recombination machinery.
品种的中着丝粒单染色体,将分离到的单染色体放入0。
Narcissus monosomes with middle centromeres were isolated with glass needles with the help of micromanipulator and then put into 0.
结果64%的卵细胞核型正常,36%的卵细胞为非整倍体,其中22%为同源染色体不分离,14%为姐妹染色单体非平衡性过早分离。
Results 64% of oocytes were normal, 36% of oocytes were aneuploidy, of which 22% were due to nondisjunction and 14% unbalanced predivision.
解决了激光显微分离系统染色体样本制备的难题,使杨树花粉母细胞减数分裂染色体激光显微分离成为可能。
Some results as follows, 1. Chromosome preparation for laser micro-dissection system was solved, which indicated that laser micro-dissection of PMCs meiotic chromosomes in Populus was feasible.
我们建立了1种易于使用的于含15种染色体微卫星标志的多重PCR中对鼠弓形虫进行分离株基因分型的方法。
We developed an easy-to-use method for genotyping Toxoplasma gondii isolates in a single multiplex PCR assay with 15 microsatellite markers.
我们建立了1种易于使用的于含15种染色体微卫星标志的多重PCR中对鼠弓形虫进行分离株基因分型的方法。
We developed an easy-to-use method for genotyping Toxoplasma gondii isolates in a single multiplex PCR assay with 15 microsatellite markers.
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