胚胎中的未分化细胞按被定型的命运不可逆地发育成特定类型细胞的过程。
Developmental program — The process by which a cell in an embryo achieves its fate.
本病为最恶性的甲状腺癌,见于老年人,病理各异,包括纺锤状、鳞状和未分化细胞。
This is a particularly virulent form of thyroid carcinoma. It occurs in the elderly and has a variable pathology, including spindle, squamous, and anaplastic cells.
结论角膜及角膜缘表层上皮较为成熟分化,而角膜缘基底细胞具有未分化细胞的特征,很可能是干细胞的部位。
ConclusionThe superficial cells of limbus and cornea are of mature status, while limbal basal cells show some undifferentiated feature, which indicates the location of stem cells.
其具有独特的发育成功能完全相同的未分化细胞的能力,同时,如果需要,他们又能分化成具有特定功能的不同类型的细胞。
They have the unique ability to develop from identical, unspecialized cells and then differentiate into distinct types of cells with special functions.
一些通常在发育胚胎中活跃的基因会被分化细胞(比如皮肤细胞)表达,促使细胞回复到未分化状态。
A handful of genes that are normally active in the developing embryo are expressed in a differentiated cell, such as a skin cell, causing that cell to revert back to its undifferentiated state.
未分化人胚胎干细胞表达VEGFR - 2,并在分化时持续表达。
Undifferentiated human embryonic stem cells express VEGFR-2, and VEGFR-2 expression persists on differentiation.
这就引出问题,转录因子是否能直接诱导其它明确的体细胞,而不仅是未分化状态的细胞。
This raised the question of whether transcription factors could directly induce other defined somatic cell fates, and not only an undifferentiated state.
例如,未分化的胚胎干细胞可能形成肿瘤,如果在移植前细胞未全部成功分化,将可能造成癌症。
Undifferentiated es cells can form tumors, for instance, creating a risk of cancer if the cells are not all successfully differentiated before transplantation.
鼻咽癌是主要的未分化癌(89%),然而非鼻咽部上呼吸道癌主要是鳞状细胞癌(88%)。
Nasopharyngeal cancers were primarily undifferentiated carcinomas (89%), whereas nonnasopharyngeal upper respiratory tract carcinomas were predominantly squamous cell (88%).
在这里,我们发现,真正的未分化单核细胞居住在脾脏,其数量超过在循环中的水平。
Here we show that bona fide undifferentiated monocytes reside in the spleen and outnumber their equivalents in circulation.
方法:通过膜片钳手段,测量未分化的SHSY5Y细胞钙离子通道电流;
Methods: By using patch clamp technique, measure voltage gated calcium currents in undifferentiated SH SY5Y cell line.
相反,这些未分化的细胞持续增殖,导致ALL。
Instead, these undifferentiated cells continue to multiply, causing ALL.
早期生长晕内可见成群的纤毛细胞,以后逐渐呈现鳞状终未分化。
Islands of ciliated epithelial cells were present in the early stage of outgrowth of expiant tissues. Gradually the epithelial cell under-went squamous differentiation.
目的:探讨食管原发性未分化小细胞癌临床病理特点。
Objective: To investigate the clinicopathologic features of undifferentiated small cell carcinoma of esophagus.
和10%四组中,2.5%血清有利于精原细胞生长并形成较多的集落,同时有利于维持精原细胞的未分化状态。
Among 0%, 2.5%, 5% and 10% groups, 2.5% FBS had profit on spermatogonial cells to grow and form more cell colonies, and profited to keep their undifferentiation state.
胚胎干细胞(ES细胞)具有自我更新、无限增殖、保持未分化状态和向所有三个胚层分化的潜能。
Embryonic stem cells (ES cells) are unique cell populations with the ability of self-renewal, unlimited proliferation, multipotent differentiation and maintaining their undifferentiated state.
结论:取用角膜缘基底组织进行培养,将无钙培养液与低钙培养基结合,可获得较纯的、未分化的角膜缘干细胞。
CONCLUSION: the relatively pure and undifferentiated limbal stem cells can be obtained by combining non calcium medium and low calcium medium after the basal limbal cell tissues are cultured.
异常细胞是积极成长(未分化)。
其是一种具有特殊组织学表现的低分化或未分化癌,浸润的淋巴细胞以T细胞为主。
It was a kind of poor differentiation or undifferentiated carcinoma with special histologic expression, the majority of infiltration lymphocytes comprised t cells.
为维持细胞在培养过程中的未分化状态,需要采用饲养层细胞培养,同时设计合理的培养液配方并添加多种抑制分化或促进增殖的细胞因子。
Feeder layer cells and suitable culture medium that supplemented with cytokines of promoting proliferation or restraining differentiation were crucial to keep chicken es in an undifferentiated state.
观察不同浓度的紫杉醇对人甲状腺未分化癌细胞DRO生长的影响。
To investigate the proliferative effect of paclitaxel against humananaplastic thyroid carcinoma cells (DRO).
未分化型细胞可能是起源细胞。
转移性未分化癌,尤其是小细胞间变型,大多来自肺。
Most of the metastatic undifferentiated carcinomas are from lungs, especially the anaplastic carcinomas of small cell type.
利用所述方法分离的未分化人胚胎干细胞在细胞疗法中可以是非常有利的。
Undifferentiated human embryonic stem cells isolated by the method may be useful in cell therapy.
结论HPESCRG1基因是一个人类ES细胞中表达特异性新基因,很可能与人类ES细胞的自我更新和维持其未分化状态密切相关。
Conclusion HPESCRG1 was found to be a novel gene expressed specifically in human es cell, which might be related to self renewal of human es cell and maintaining its undifferentiated state.
单细胞反转录酶聚合链式反应检测胰岛素促进因子基因实验中,选择12个单个胰腺干细胞进行检测,另取12个单个未分化的干细胞作为对照。
In the detection of IPF1 gene with single cell RT-PCR, 12 single pancreatic stem cells were detected, and another 12 undifferentiated single pancreatic stem cells were taken as controls.
单细胞反转录酶聚合链式反应检测胰岛素促进因子基因实验中,选择12个单个胰腺干细胞进行检测,另取12个单个未分化的干细胞作为对照。
In the detection of IPF1 gene with single cell RT-PCR, 12 single pancreatic stem cells were detected, and another 12 undifferentiated single pancreatic stem cells were taken as controls.
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