结果VEGF是对内皮细胞特异的有丝分裂原，也有提高血管通透性的作用，在缺氧条件下作用尤为显著。
Results VEGF, as a mitogen specifically for endothelial cells, could strongly stimulate angiogenesis as well as vascular permeability, especially in hypoxia state.
表皮生长因子受体(EGFR)在人类肝细胞广泛表达，表皮生长因子可能是肝细胞生长中必须的有丝分裂原。
Epidermal growth factor receptor (EGFR) is frequently expressed in human hepatoma cells, and EGF may be one of the mitogens that are needed for the growth of hepatoma cells.
促有丝分裂原活化蛋白激酶（MAPK）信号传导途径与细胞生长、分化、凋亡等密切相关，在介导细胞凋亡过程中起着重要作用。
Mitogen-activated protein kinase pathway may closely associated with cell growth, differentiation and apoptosis, it may play an important role in cell death.
它既可以作为整合各种信号转导通路的上游信号如胰岛素、生长因子和有丝分裂原的整合器，又可以作为感知细胞内营养与能量水平及还原状态的感受器。
It combines input from multiple upstream pathways, including insulin, growth factors and mitogens while functioning as a sensor of cellular nutrient and energy levels and redox status.
它既可以作为整合各种信号转导通路的上游信号如胰岛素、生长因子和有丝分裂原的整合器，又可以作为感知细胞内营养与能量水平及还原状态的感受器。
It combines input from multiple upstream pathways, including insulin, growth factors and mitogens while functioning as a sensor of cellular nutrient and energy levels and redox status.
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