最大的问题是，网上读者所带来的收益远不及印刷版读者带来的收益多。
The biggest problem is that readers online bring in nowhere near the revenues that print readers do.
最大的问题是，夫妻双方都认为对方知道他们的财务状况，但事实并非如此。
The biggest problem is that couples assume each other knows what's going on with their finances, but actually they don't.
分析者说，最大的问题是高失业率，这会导致借贷需求减少以及银行不愿意放贷。
Analysts say the biggest problem is high unemployment, which weakens demand and makes banks reluctant to lend.
世界上最大的问题是海平面上升，冰川造成了21%的海平面上升。
The biggest problem to the world is rising sea levels, glaciers are responsible for 21% of sea level rise.
从这么深的地方抽水，最大的问题是地表会逐渐下沉。
The biggest concern of pumping out water from this deep is the gradual settling down of the land surface.
我想，我应该吃点什么，或者喝点什么；可最大的问题是，有什么？
I suppose I ought to eat or drink something or other; but the great question is, what?
一位专家表示，最大的问题是海滩附近的酒店、船只和海洋中的塑料垃圾。
An expert said the biggest problems were hotels by the beaches, boats, and plastic waste in the sea.
最大的问题是能源安全耗费金钱。
最大的问题是那些纳米纤维不能潮湿。
不过，最大的问题是欧洲将逐渐失去耐心。
But the biggest problem is that Europe will gradually lose patience.
当我们谈到成本，最大的问题是初始阶段。
When it comes to cost, the biggest issue is getting started.
最大的问题是他的薪酬。
最大的问题是谁将成为提供者。
最大的问题是资源，尤其是时间。
最大的问题是她不觉得自己有问题。
The real problem was that she didn't think she had a problem.
最大的问题是，美国将采取什么行动？
最大的问题是PC仪器怎样与传统仪器遭遇的？
The bigger question is how PC-based instruments fare against traditional instruments.
可是，也许他最大的问题是他自我感觉不能赢。
Perhaps his biggest problem, though, was the self-fulfilling perception that he could not win.
两者之间最大的问题是争夺。
最大的问题是脸谱对隐私潜在的偏见。
The worst thing is Facebook's underlying prejudice against privacy.
最大的问题是如何保持一个正常的步伐。
不过，日本人最大的问题是想象力匮乏。
But the greatest handicap of the Japanese is their lack of imagination.
最大的问题是：毒性如何？
所以我猜想最大的问题是你如何奉献给其他人价值？
So I guess the biggest question is how can you give value to other people?
现在，最大的问题是这会在什么时候发生。
然而，乔拜登最大的问题是他不是希拉里·克林顿。
Mr Biden's biggest problem, however, is that he is not Hillary Clinton.
最大的问题是：“交易是可以掌握的吗？”
最大的问题是苹果公司是否可以迎头赶上.
最大的问题是人们在家里将如何对付电脑？
The big question was what would people do with a computer in their home?
最大的问题是人们在家里将如何对付电脑？
The big question was what would people do with a computer in their home?
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