目的探讨奇曼丁 （曲马多缓释片 ）对晚期癌症中度疼痛的疗效及其副作用。
Objective To observe the analgesic effect of morphine hydrochloride sustained-release tablets on cancer patients at late stage.
方法分别采用不同黏度与用量的羟丙甲纤维素(HPMC)，不同主药粒径与稀释剂，不同工艺制备盐酸曲马多缓释片。
METHODS Different particle size of tramadol hydrochloride, viscosity grades and the amount of HPMC, additive content and process were used to prepare tramadol hydrochloride sustained release tablets.
方法分别采用不同黏度与用量的羟丙甲纤维素(HPMC)，不同主药粒径与稀释剂，不同工艺制备盐酸曲马多缓释片。
METHODS Different particle size of tramadol hydrochloride, viscosity grades and the amount of HPMC, additive content and process were used to prepare tramadol hydrochloride sustained release tablets.
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