肝星状细胞是一种与肝纤维化密切相关的主要的细胞种类，它在肝受到损伤时形成瘢痕组织。
HSCs are the major cell type involved in liver fibrosis, which is the formation of scar tissue in response to liver damage.
肝星状细胞、成纤维细胞和窦状隙内皮细胞是肝内ctgf的重要来源。
It can be concluded that CTGF was mainly produced in hepatic stellate cells, sinusoidal endothelial cells and fibroblasts.
肝星状细胞的激活、表型改变并分泌大量的细胞外基质是肝纤维化发生的中心环节。
The activation of hepatic stellate cell phenotype change and secretion of extracellular matrix of liver fibrosis is the central link.
控制肝星状细胞的激活和增殖并逆肝纤维化的进程是抗肝纤维化研究的重点之一。
The manipulation of the activation and proliferation of hepatic stellate cells and the process of liver fibrosis inversion are the key in anti-liver-fibrosis researches.
结论：甘草甜素能诱导肝星状细胞铁蛋白重链的表达。调控铁蛋白重链基因的表达可能是甘草甜素抗肝纤维化作用的分子生物学机制之一。
Conclusion: glycyrrhizin could up-regulate the expression of ferritin heavy chain gene in hepatic stellate cells, which may contribute to the anti fibrosis of glycyrrhizin.
结论：甘草甜素能诱导肝星状细胞铁蛋白重链的表达。调控铁蛋白重链基因的表达可能是甘草甜素抗肝纤维化作用的分子生物学机制之一。
Conclusion: glycyrrhizin could up-regulate the expression of ferritin heavy chain gene in hepatic stellate cells, which may contribute to the anti fibrosis of glycyrrhizin.
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