现对常见的肾小球肾炎的动物模型及其在新药评价中的作用进行综述。
The animal models mimicked common glomerulonephritis and their uses in new drug evaluation are reviewed in this article.
然而，研究人员和制药商却大幅削减了用于对新药剂进行评价和临床试验的资金。
However, researchers and pharmaceutical manufacturers have significantly cut back on funds for the evaluation and clinical testing of new agents.
美国食品药品监督管理局称这些新药的评价将基于患者不确定使用的假设上。
The FDA has said it will evaluate the new drugs under the assumption that patients would use them indefinitely.
从有机合成原理及合成工艺的角度介绍了抗胃溃疡新药奥美拉唑的各种合成方法，并评价了其优缺点。
Synthesis methods, principle and technology were reviewed for new drug Omeprazole of peptic antiulcer, their advantages and disadvantages were described.
建立合理的药动学筛选模型不仅可以降低新药开发的成本，并且可以在新药研究早期对其作出正确的评价。
Establishing rational pharmacokinetic screening models can not only decrease the cost of finding new drugs, but also give a correct evaluation at the beginning of drug research.
方法：统计2001～2006年四川省中药新药及按新药管理的中药申报注册的数据资料，并进行分析和评价。
METHODS: The data of the application and registration of TCM treated as new medicine and new TCM in Sichuan province from 2001 to 2006 were analyzed and evaluated statistically.
药物安全评价是新药开发过程中不可缺少的部分。
Assessment of drug safety is the necessary part in the course of development of new drugs.
结果：根据模型的评价结果，可以对新药研发项目进行优选排序。
RESULTS:The new drug research&development projects can be optimized and ranked based on the evaluation results on the model.
目的：评价国产新药利福昔明胶囊治疗细菌感染性腹泻的有效性与安全性。
AIM: To evaluate the safety and efficacy of domestic rifaximin in the treatment of acute bacterial infectious diarrhea.
本文介绍了抗hiv新药奈韦拉平的合成路线研究进展，并评价了其优缺点。
Synthesis methods for new drug Nevirapine of HIV were reviewed and their advantages and disadvantages were described in this paper.
研究CYP450对新药设计、筛选、评价及优化有重要意义。
Research on genetic polymorphism of CYP450s is significant to drug design, screening, evaluation and optimization.
方法以对照菌回收为主要内容，进行了16 4个新药产品的验证试验，用样本组和对照组之间的回收率对有效性进行评价。
METHOD The validation have been tested by microbial recovery from 164 new drugs and the availability was estimated by the ratio of recovery from the test group to the control group.
目的：将负二项回归用于新药的安全性评价，以此分析评价不良事件的发生情况。
AIM: to apply negative binomial model for the safety assessment of a new drug, so as to analyze the occurrence of adverse events.
CHL细胞引自国家沈阳新药安全评价研究中心。
CHL cells were bought from National Safety and Evaluation Center of the New Drug (Shenyang).
科学地对中药新药的疗效进行评价，有利于弘扬祖国医学。
Scientific evaluation of therapeutic effects of new TCM drugs makes a key link in boosting the TCM development.
然而，在确保进口食品(56%)和药品(52%)的安全方面，大多数人仍然给了美国食品和药物管理局(FDA)负面评价，还有在加速新药上市方面(54%)。
However, most people still give the FDA negative ratings on ensuring the safety of imported food (56%) and drugs (52%), and on getting new drugs to the market more quickly (54%).
介绍了抗胃溃疡新药奥美拉唑的各种合成方法，并评价了其优缺点。
Synthesis methods, principle and technology were reviewed for new drug Omeprazole of peptic antiulcer, their advantages and disadvantages were described.
结果与结论：我国应制订药物经济学评价指南并应用于药品定价、报销目录遴选、临床合理用药、疾病防治策略以及新药研发等卫生决策领域。
RESULTS &CONCLUSION:It's necessary for China to formulate pharmacoeconomic guidelines and use it in drug pricing, drug reimbursement, clinical guidance, diseases prevention and new drug R&D.
目的在中国健康成年志愿者中评价单剂和多剂静注国家注册一类新药注射用尖吻蝮蛇血凝酶的安全性、耐受性。
OBJECTIVE To evaluate the safety and tolerability of single dose and multi dose injection of heamocoagulase agkistrodon(HCA)in Chinese healthy volunteers.
心肌损伤生物标志物的检测在心脏疾病临床诊断上被广泛应用，但是在新药的非临床安全评价方面，心肌损伤标志物的应用相对滞后。
The biomarkers of myocardial injury are used widely in clinical diagnosis of heart diseases. However, application of the biomarker in drug preclinical safety evaluation is relatively less.
由于新药上市前临床试验存在许多局限性，故上市后药品再评价非常重要。
The re-evaluation of the effectiveness of new drugs is of great importance when they are in post-market for there exist some limitations in clinical trials before these drugs are put on the market.
丙二醛的测定，比直接检测前列腺素简便，有助于了解血小板前列腺素代谢，可用以评价血小板功能以及疾病或某些新药对血小板功能的影响。
The measurement of MDA in platelets is much simpler than the direct detection of prostaglandin. It contributes to a better understanding of platelet p...
丙二醛的测定，比直接检测前列腺素简便，有助于了解血小板前列腺素代谢，可用以评价血小板功能以及疾病或某些新药对血小板功能的影响。
The measurement of MDA in platelets is much simpler than the direct detection of prostaglandin. It contributes to a better understanding of platelet p...
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