研究CYP450对新药设计、筛选、评价及优化有重要意义。
Research on genetic polymorphism of CYP450s is significant to drug design, screening, evaluation and optimization.
本文在前人研究的基础上,以PHR0007为先导化合物,按着新药设计原理合成了10个未见文献报道的化合物。
In this paper, according to the principles of new drug design, On the basis of former research the 10 compounds guided by the lead compound PHR0007 were synthesized.
用药物靶子的三维结构作为起点进行新药分子的系统化设计。
The systematic design of new drug molecules using the three-dimensional structure of the drug target as a starting point.
现在,MIT癌症生物学家已经展现了耐药性是如何增加的,这项发现可能帮助研究员设计可以克服顺铂耐药性的新药。
Now, MIT cancer biologists have shown how that resistance arises, a finding that could help researchers design new drugs that overcome cisplatin resistance.
的确,那些设计飞机的设计师,寻找石油矿藏的工程师;还有制造新药的药剂师已经用三维技术多年了。
Indeed, the folks who design airplanes, search for oil deposits, and create new drugs have been hip to 3d for years.
不管是为了制造新药物还是太阳能板,我们不断地奋力设计、建造复杂的新分子。
Whether for a new drug or solar cell, we constantly strive to design and build intricate new molecules.
以镜像方式对称的分子通常会具有不同的性质,于是研究人员利用这种“手性(chirality,译注:指分子的左/右手螺旋性质)”来设计新药物。
Molecules often come in mirror images that can have different properties, and researchers take advantage of this "chirality" to design new drugs.
按《中医新药临床研究指导原则(试行)》2002版准设计调查表,准确填写临床资料。
Refer to Directions of new drugs clinical research (try out) 2002, we designed the measuring scale and collected the clinical data.
每条通路都是设计新药逆转T细胞关闭的目标。
Each pathway represents a target for the design of new drugs to reverse t cell shutdown.
科学家接着可设计到达细胞内特定位置的新药以更有效的发挥作用。
Scientists could then design new drugs to go to specific places within cells to work more efficiently.
这些现象的声音知识怎样被包含进有效的新药候选者的设计,这也被解释。
How a sound knowledge of these phenomena is incorporated into the design of effective new drug candidates is also explained.
设计了利用因特网上多个集群的空闲资源来处理生物医学领域数据密集型计算的新药研发网格(DDG)。
Utilizing the idle resources donated by the clusters that scatter over the Internet, drug discovery grid (DDG) can implement efficient data-intensive biologic applications.
本文设计的基于动物活动数据监测的记录仪,其目的在于检验新药品的药效,为进一步的临床实验打下基础。
The recording equipment designed in the dissertation is used to detect animal activity. The purpose of it is to test the effect of a new medicine and get a good ready for clinic experiment.
计算机辅助药物分子设计近年来已成为新药创制的重要手段。 基于结构的合理药物分子设计则是多学科交互融合和渗透的体现。
Computer-aided molecular design (CAMD) is now an uprising subject in medicinal chemistry among which structure-based rational drug design is attracting more and more attention.
结果表明,新药剂的性能能够满足设计指标要求。
The results indicate the performances of the new charge can satisfy the requirements of design index.
该文综述了药物靶标的发现、基于靶标的药物设计及其在新药研究中的应用前景。
This article reviews the drug target's discovery, drug design based on targets, as well as prospects in developing novel drug.
超级计算机可帮助解决最棘手的科学问题,包括像模拟新药等商业产品以及模拟如武器设计和破译密码等防务相关的应用。
Super computers help tackle the toughest scientific problems, including simulating commercial products like new drugs and defense-related applications such as weapons design and code breaking.
文章讨论了在新药物发现与设计中化学分子数据库的结构、设计和应用软件的开发。
This paper discusses the structure, design and software development of molecular multimedia databases for drug discovery.
新药研究中剂量与效应关系研究贯穿于各期临床试验中,可变剂量设计具有一定优势。
Titration to optimal effect is the central principle in the treatment of diseases with medications, and an important approach for the study of dose-response relationship.
将间隙连接作为靶点设计抗癌新药物,将为肿瘤治疗提供新方向。
It may provide a novel therapeutic target for tumor treatment when utilize connexin to design new anti-cancer drug.
针对这些情况,建立了一套采用试验设计、支持向量机方法进行新药试生产的系统。
Aiming at these situations, a new-medicines' preproduction system was presented, which was based on experiment-design and support-vector-machines methods.
针对这些情况,建立了一套采用试验设计、支持向量机方法进行新药试生产的系统。
Aiming at these situations, a new-medicines' preproduction system was presented, which was based on experiment-design and support-vector-machines methods.
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