目的：探讨微观进化在新生隐球菌感染中的作用。
Objectives: to discuss the role of microevolution of Cryptococcus neoformans.
目的探讨新生隐球菌多糖荚膜在小鼠原发性皮肤新生隐球菌感染中的作用。
Objective to investigate the role of capsule of Cryptococcus neoformans in mice cutaneous infection.
目的：评价不同孵育条件、来源和血清型的新生隐球菌分泌磷脂酶的活力情况。
Objective: to evaluate the activity of phospholipase secreted by cryptococcus neoformans from different sources, serotypes and incubation conditions.
结果：新生隐球菌黑色素的产生受多种因素的影响，其中以氮源、葡萄糖和温度的影响最为明显。
Results: the production of c. neoformans melanin was affected by various factors, in which nitrogen source and glucose affected it obviously.
方法对本院1980— 2 0 0 4年确诊的19例新生隐球菌脑膜炎病人的诊断情况进行回顾分析。
Methods The diagnosis situation of 19 cases of cryptococcal meningitis who have been confirmed from 1980 to 2004 are analysed.
方法利用二维凝胶电泳获得新生隐球菌孵育后血管内皮细胞与正常细胞差异表达蛋白质点，并对部分差异蛋白点进行质谱鉴定分析。
Methods The differentially expressed proteins between HUVEC incubated with Cryptococcus and normal HUVEC were obtained by 2-D electrophoresis and identified by MALDI-TOF MS technology.
方法利用二维凝胶电泳获得新生隐球菌孵育后血管内皮细胞与正常细胞差异表达蛋白质点，并对部分差异蛋白点进行质谱鉴定分析。
Methods The differentially expressed proteins between HUVEC incubated with Cryptococcus and normal HUVEC were obtained by 2-D electrophoresis and identified by MALDI-TOF MS technology.
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