黄芩素纳米混悬液口服给药可显著提高生物利用度。
Baicalein nanosuspension by oral administration could significantly enhance the bioavailability in rats.
结果该制剂可以延长药物在胃内的滞留时间,提高生物利用度。
Results This preparation had the advantages of prolonging the gastric retention time and enhancing the bioavailability.
结果该剂型可以延长药物在胃内的滞留时间,提高生物利用度并减少给药次数。
Results Hollow microspheres have the advantage of prolonging the gastric retention time, enhancing the bioavailability and decreasing dosing frequency.
目的将阿莫西林制成胃漂浮缓释片,延长在胃中的停留时间,逐渐释放,提高生物利用度。
Objective to manufacture Amoxicillin into gastric floating sustained release tablets, which can extend their stay time in stomach to make Amoxicillin release slowly and to increase bioavailability.
目的:研制青蒿素缓释固体分散物,提高其制剂的生物利用度。
Aim In order to increase bioavailability of Artemisinin'S dosage form, solid dispersion of Artemisinin was prepared.
固体脂质纳米粒作为一种新型给药系统,可以提高难溶性药物生物利用度。
Solid lipid nanoparticles is a new drug delivery system, which can enhance the bioavailability of poorly soluble drugs.
本工作将SOD制成微球,以提高SOD稳定性和口服相对生物利用度,且在微球制备条件方面作了进一步研究。
In this work, SOD gelatin microspheres were made with the aim to improve its stability, oral relative bioavailability, and to study the preparation conditions of microspheres.
自乳化药物传递系统可显著地提高难溶性或亲脂性药物口服生物利用度,具有广阔的发展前景。
The SEDDS can dramatically improve the bioavailability of poorly water soluble or lipophilic drugs by oral administration. SEDDS will have a good developmental potential.
结果纳米颗粒转运系统能够保护被转运的基因,有较高的转染效率,具有良好的靶向性,并且提高了药物的生物利用度,显示出一定的缓控释作用。
Results Nanoparticle carrier system can protect the genes, have a high carrying efficiency and a well targeting property, it also can improve the bioavailability, sustained and controlled release.
讨论了影响自胃肠道吸收药物生物利用度的因素,对提高难溶性药物口服生物利用度的方法进行了综述。
Factors that affect the oral bioavailability of water insoluble drugs were discussed, and a review was given on the measures of improving the oral bioavailability of water insoluble drugs.
就固体脂质纳米粒提高难溶性药物生物利用度的机理及应用作一介绍。
This paper reviews the mechanism and application of SLN for enhancing the bioavailability of poorly soluble drugs.
结论超微粉碎技术可促进大黄有效成分的吸收,提高其生物利用度。
Conclusion rhubarb ultra-fine powder can promote the absorption of active ingredients in rhubarb and increase bioavailability of rhubarb powder.
结论0.3%左氧氟沙星透明质酸钠滴眼液同对照组比较,其相对生物利用度显著提高。
ConclusionThe ocular bioavailability of 0.3% levofloxacin-SA was significantly higher than that of 0.3% levofloxacin.
本文就胡椒碱提高药物生物利用度的机制进行综述。
In this article, we summarized the advances on mechanism of how Piperine enhance the bioavailability of drugs.
糖蛋白抑制剂可促进药物通过血脑屏障,对提高脑内药物的浓度和中枢神经系统药物的生物利用度具有重要意义。
P-glycoprotein inhibitors can get drugs across the blood-brain barrier. It is of great importance to improve the blood concentration in brain and bioavailability of central nervous system drugs.
该药物扩大了适用人群,提高了生物利用度和疗效。质量可控,宜于工业化生产,具有重要的实用价值。
The medicine of the present invention has expanded applicable people, high bioavailability, raised curative effect and controllable quality, and is suitable for industrial production.
结果表明,醋甲唑胺的眼用混悬剂可以显著提高药物在眼内的生物利用度,达到了局部用药制剂的设计要求。
These results indicate that the ophthalmic suspensions increased the bioavailability of MTZ in the eye aqueous humor, which is of significance in the development of topical dosage form of MTZ.
目的:研制非诺洛芬钙肠溶胶囊(FCEC),提高非诺洛芬钙(FC)的溶出度及生物利用度。
OBJECTIVE:To study fenoprofen calcium enteric capsules(FCEC) and increase the dissolution and bioavailability of fenoprofen calcium(FC).
既利用透明质酸对癌细胞的靶向性,提高了紫杉醇的生物利用度,又达到了药物缓释的效果。
HA with a specific targeting property could increase the bioavailability of paclitaxel and control the release rate of the drug.
卵磷脂对水飞蓟宾的抗急性肝损伤具有协同作用,其不仅通过提高水飞蓟宾的生物利用度增强药效,而且其自身也具有保肝作用。
The hepatoprotective potential of SPC was improved not only by the improvement of bioavailability of silybin according to complex silybin with PC, also by the synergic action of PC.
目的为了增加阿昔洛韦在皮肤中的滞留量,提高局部生物利用度,制备了阿昔洛韦棕榈酸酯脂质体凝胶剂。
OBJECTIVE to prepare the acyclovir ACV palmitate liposome gel in order to raise ACV concentration in the skin and enhance the topical bioavailability of ACV.
此包合物经兔鼻腔灌流后,家兔血液中药物的浓度,筛鼻甲、大脑、嗅脑部分的吸收量均高于水饱和溶液,细辛脑的生物利用度得到提高;
So after rabbit nasal Were perfused compound of with hydroxypropyl-P-cyclodextrin liquid, drag concentrations of Asarone of various parts were higher than that of water-saturated solution;
此包合物经兔鼻腔灌流后,家兔血液中药物的浓度,筛鼻甲、大脑、嗅脑部分的吸收量均高于水饱和溶液,细辛脑的生物利用度得到提高;
So after rabbit nasal Were perfused compound of with hydroxypropyl-P-cyclodextrin liquid, drag concentrations of Asarone of various parts were higher than that of water-saturated solution;
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