结论:盐酸氨溴索渗透泵控释片释药稳定,零级释药明显,具备优良控释制剂的特征。
Conclusions: The ambroxol HCl osmotic pump controlled release tablets have a stable release curve and conform to zero release order.
为此我们对中药的缓释和控释系统、靶向给药系统等新型给药系统的研究进行了综述。
Thus we review the recent advances on the new drug-delivery system of TCM, such as the sustained and controlled release delivery system, target delivery system.
结论通过乳化缩聚法制成一种缓控释靶向给药新剂型——微球。
Conclusions: make a new kind of pharmaceutical dosage form-microparticles. through emulsification condensation method.
结论采用均匀设计法优选的配方组成符合骨架控释型透皮给药系统的要求。
Conclusion the prescription composition optimized by uniform design meets the requirement of skeleton-controlled transdermal delivery system.
选择壳聚糖作为透皮给药系统的控释材料,并对壳聚糖的成膜条件进行了研究。
Chitosan was chosen as the controlling materials for the transdermal drug delivery system, and the conditions of preparing chitosan membranes were researched.
目的制备盐酸昂丹司琼渗透泵型控释片剂(OND - OPT)并考察体外释药特性。
Aim To prepare ondansetron hydrochloride osmotic pump tablets (OND-OPT) and investigate their in vitro drug release behavior.
结果表明,该聚氨酯压敏胶贴剂具有良好的药物控释能力,适用于经皮给药系统。
The results indicated that the hydrophilic polyurethane PSA prepared show good transdermal drug release properties, which suit for the TDDs application.
柠檬酸根交联壳聚糖膜在SGF中的溶胀以及药物的释放速率比在SIF大得多,这表明这些膜有望作为胃部给药的控释载体。
The swelling ratio and drug release rate of citrate cross-linked chitosan in SGF was much more quick than that in SIF, so these film may be used as a drug carrier in the stomach.
口服液体控释给药系统是一种新型药物传递系统,因其存在物理不稳定性,所以能上市的品种较少。
Oral liquid drug controlled release system (OLCRS) is a new drug delivery system. But only a few has been come into the market due to the physical instability.
结果:制备的黄杨宁渗透泵控释片体外释药速度较平稳。
Results:Preparation of Huangyangning osmotic pump controlled release tablets in vitro release rate of more stable.
药物的初始释放速率和传统经皮给药控释系统相近,释药量与储库层药物含量无关;
The release rate of composite patches was similar to that of traditional patches at the beginning but was larger on average.
阐述了靶向型药物控释体系控制释药的原理和相关材料。
Expounding the mechanism and relative material of the drug control release in the systems for drug targeting and controlled release.
目的:改善磁性顺铂微球的药突释和滞释,实现控释。
Objective: Improving drug burst release and stagnant release of magnetic cisplatin microspheres (MCM) and achieving controlled release.
结论阿魏酸钠单层渗透泵控释片工艺稳定,呈明显的零级释药特征。
Conclusion The drug release of sodium ferulate single-layer osmotic pump controlled release tablets is stable and had obvious characteristic of zero release.
介绍缓释制剂、控释制剂、靶向给药系统等的原理及制备方法。
And it introduces the principle and preparation method such as sustained or controlled release dosage forms, targeted drug delivery system etc.
目的:研究高脂食物对氨茶碱控释片药代动力学的影响。
The effect of high fat diet on the pharmacokinetics of theophylline from controlled release aminophylline tablets has been observed in six healthy volunteers.
它们在靶向给药、药物控释、基因治疗、药物筛选、细菌与病毒的鉴定等方面有着非常有效的应用。
They to give the medicine, the medicine in the target to control release, gene therapy, medicine screening, bacterium and virus's aspects and so on appraisal have the very effective application.
目的研究渗透泵型控释片剂的释药规律及释药重现性,探索考察释药机制的新方法。
OBJECTIVE to improve the drug release reproducibility of elementary osmotic pump tablets and to investigate its drug release mechanism with a new method.
单因素考察发现,影响释药时滞和释药速率的主要因素为溶胀层中高效崩解剂比例、溶胀层增重及控释层增重。
The factors which affect the lag time and drug release behavior were investigated, such as the thickness of the inner and outer layers, the amount of PVPP and other excipients, etc.
本文重点介绍了一些新的给药途径和给药系统,例如鼻腔、颊等给药途径以及黏膜给药系统、透皮给药系统、缓控释技术等给药系统的进展。
The effect of buccal mucosa in different regions on penetration and absorption of drugs, various and quality evaluation methods of buccal mucosa drug delivery system are introduced.
本文观察硫酸吗啡控释片(美施康定) ,经直肠给药治疗终末期癌症患者疼痛的效果。
An observation was made by the pain relieving effect of morphine sulfate controlled-release tablets(MS Contin) given by rectal route to 30 advanced cancer patients in their final stage.
该文就抗菌药物在牙周病治疗中的地位,牙周局部抗菌缓控释制剂的优点、释药原理和类型、现有制剂和应用效果、面临的问题和展望等作一综述。
In this paper, the advantages, drug-releasing mechanisms, types of preparation, existing preparations and their application, and future prospects of sustained-releasing antimicrobial preparation...
该文就抗菌药物在牙周病治疗中的地位,牙周局部抗菌缓控释制剂的优点、释药原理和类型、现有制剂和应用效果、面临的问题和展望等作一综述。
In this paper, the advantages, drug-releasing mechanisms, types of preparation, existing preparations and their application, and future prospects of sustained-releasing antimicrobial preparation...
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