本文综述了口服缓控释制剂研究概况。
In this article the research on oral sustained and controlled release preparations is surveyed.
本制粒法可用于水溶性药物控释制剂的制备。
These results suggested that this granulation method was useful in preparing a sustained release preparation of water soluble medicine.
结论相似因子法适合于缓控释制剂体外释放的评价。
ConclusionsThe similarity factor is fit for evaluation of sustained or controlled...
介绍缓释制剂、控释制剂、靶向给药系统等的原理及制备方法。
And it introduces the principle and preparation method such as sustained or controlled release dosage forms, targeted drug delivery system etc.
因此,多层骨架片系统是制备高水溶性药物控释制剂的有效方法。
The system of multi-layered matrix tablets provided an effective method for zero-order release of highly soluble drugs.
在上世纪70年代,国外就开始了缓控释制剂及材料的研究开发。
Early in the 1970s, the slow-release and controlled-release preparation and the corresponding materials had been researched.
我们对渗透泵型控释制剂的研究,从包衣膜和片芯处方两个方面着手。
Our research in osmotic pump formulations will start from two aspects, the core prescription and the coating film.
结论钙拮抗药应用趋势是二氢吡啶类药物前景看好,缓、控释制剂应用将更普遍。
Conclusions Dihydropyridine calcium antagonist is promising, and the sustained release preparation or controlled release preparation would be more and more frequently used.
结论:采用控释薄膜包衣技术和骨架控释技术可用于制备强水溶性药物控释制剂。
CONCLUSION: the controlled release film-coated technique and the matrix technique can be used to prepare controlled release tablets for highly hydrophilic drugs.
方法:通过对我院2000年度住院患者使用的口服缓、控释制剂的用法进行调查。
Method: To investigate the administration method by the inpatient in our hospital in 2000.
结论:盐酸氨溴索渗透泵控释片释药稳定,零级释药明显,具备优良控释制剂的特征。
Conclusions: The ambroxol HCl osmotic pump controlled release tablets have a stable release curve and conform to zero release order.
近年来国内外研制成缓释、控释制剂的主要有片剂、胶囊剂、微球剂、滴眼剂、注射植入剂等。
In recent years, many sustained-released and controlled-release agents have been prepared successfully internal and abroad, such as tablets, capsule, micro spheres, eye drops, injection implant etc.
结果羟丙基纤维素在片剂、胶囊剂、黏膜黏附制剂、缓控释制剂等多种制剂以及薄膜包衣方面均有良好应用。
RESULTS Hydroxypropyl cellulose is extensively used in tablets, capsules, mucous membrane adhesion preparation, sustained or controlled release preparation, and film coating, etc.
本发明为复方控释制剂,血药浓度波动小、降低了副作用、提高疗效、一天仅服一次、提高了患者的顺应性,具有显著的优点。
The compound controlled releasing preparation has the obvious advantages of small blood medicine concentration fluctuation, less side effect, raised curative effect and raised patient's compliance.
该文就抗菌药物在牙周病治疗中的地位,牙周局部抗菌缓控释制剂的优点、释药原理和类型、现有制剂和应用效果、面临的问题和展望等作一综述。
In this paper, the advantages, drug-releasing mechanisms, types of preparation, existing preparations and their application, and future prospects of sustained-releasing antimicrobial preparation...
对辐照灭菌技术在保健食品、酶制剂和缓控释胶囊的应用也作了专门介绍。
And the application of radiation sterilization on health food, enzyme preparation and controlled-release capsule is specially introduced.
尽管可降解聚合物微球在药物控释领域的应用已经取得了一定的进展,然而真正用于临床的微球制剂并不多。
Although the controlled release system based on biodegradable microspheres has made great progress. The application of this formulation in clinical is still very limited.
新剂型“渗透泵控释片剂”生产中的打孔要求是目前该类型制剂的研发瓶颈。
The drilling requirements in the production of a new type troche, osmotic pump control-released tablets, is the nodus in the research of this kind of medicine.
羟丙基甲基纤维素(HPMC)作为构成亲水凝胶骨架片的主要控释、缓释材料广泛用于药物的控释和缓释制剂的研究。
Hydroxypropylmethylcellulose(HPMC), as hydrophilic gel matrix, is widely applied in the study of controlled release and sustained release preparations.
本发明涉及药物制剂领域,具体涉及双层渗透泵控释片制剂及其制备方法。
The invention relates to the drug preparation field, in particular to a two-layer osmotic pump controlled release tablet preparation and a preparation method thereof.
本发明还公开了一种上述丹酚酸B肠溶控释片制剂及其制备方法。
The invention also discloses a danshinolic acid B enteric controlled-release tablet preparation and a preparation method thereof.
本发明还公开了一种上述丹酚酸B肠溶控释片制剂及其制备方法。
The invention also discloses a danshinolic acid B enteric controlled-release tablet preparation and a preparation method thereof.
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