低氧诱导因子1 (HIF - 1)是重要的氧依赖性核转录因子,低氧条件下能上调多个靶基因表达以减少缺氧性损伤。
Hypoxia inducible factor-1 (HIF-1) is a key oxygen-dependent transcription factor that up-regulates many protective genes against hypoxia-induced injury.
结论:神经干细胞在中枢神经系统疾病、基因治疗、相关的诱导分化、心肌损伤以及治愈膝关节半月板损伤等方面具有广阔应用前景。
CONCLUSION: Neural stem cells are extensively applied in central nervous system disease, gene therapy, related induced differentiation, myocardial damage, and knee meniscus injury.
目的辐射能诱导细胞基因表达的改变,机体辐射损伤效应是大量基因表达变化的结果。
Aim radiation can induce changes in gene expression in mammalian cells, and the radiation injury in an organism is also related to the expression changes of many genes.
主要讨论了UV -B信号途径及光受体,UV - B诱导的DNA损伤、转座子激活,UV - B对光合器官的分子伤害及相关基因表达的调控等。
UV B signaling pathway and specific UV B receptor, DNA damage, activation of transposons, molecular damage of photosynthetic apparatus and UV B regulation of related gene expression were included.
主要讨论了UV -B信号途径及光受体,UV - B诱导的DNA损伤、转座子激活,UV - B对光合器官的分子伤害及相关基因表达的调控等。
UV B signaling pathway and specific UV B receptor, DNA damage, activation of transposons, molecular damage of photosynthetic apparatus and UV B regulation of related gene expression were included.
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