Wright教授:一般来说,治疗丙肝,真正影响持续病毒应答率的是彻底停用利巴韦林。
Prof. Wright: In general with the treatment of hepatitis C, the thing that really impacts the SVR is if you stop ribavirin completely.
《国际肝病》:您以前的研究表明,利巴韦林用量的微小减少不会明显影响持续病毒应答率,除非剂量累计减少60%以上。
Hepatology Digest: Your previous research showed that minor ribavirin dose reductions to manage adverse events to not appear to adversely affect SVR unless cumulative exposure is less than 60%.
持续病毒学应答可以降低肝硬化和肝病并发症的发生,降低肝癌(肝细胞性癌)和死亡的发生率。
Sustained virologic response can result in decreased cirrhosis and complications of liver disease, decreased rates of liver cancer (hepatocellular carcinoma), and decreased mortality.
在两项试验中,持续的病毒学应答率为79%和80%,相比标准治疗方案,即长效干扰素联合利巴韦林的应答率50%更高。
The sustained virologic response rate was 79% and 80% in two studies, which was higher than the response rate of 50% with the standard of care with peginterferon plus ribavirin.
在两项试验中,持续的病毒学应答率为79%和80%,相比标准治疗方案,即长效干扰素联合利巴韦林的应答率50%更高。
The sustained virologic response rate was 79% and 80% in two studies, which was higher than the response rate of 50% with the standard of care with peginterferon plus ribavirin.
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