抗血管生成治疗已经成为治疗恶性血液疾病的重要策略。
The generation and development of hematological malignancies are close related to vasculogenesis, so it is an important tactic of anti-vessel growth therapy in hematological malignancies.
因此对健康组织来说,抗血管生成药物能引起广泛和非预期的副作用。
Thus, drugs that target critical angiogenesis molecules can cause a wide range of unintended side effects in healthy tissue.
内皮抑素是一种抗血管生成的抑制因子,它特异性地作用于新生微血管的内皮细胞,其水平与肿瘤血管生成有着明显的相关性。
Endostatin is a kind of angiogenesis inhibitor, specific effecting in the new microvascular endothelial cells. The level of endostatin and the angiogenesis of tumor have a close correlation.
由于抗血管生成药物具有毒性低、不易产生获得性耐药的特点。因此,通过抑制血管生成来抑制肿瘤生长成为目前肿瘤治疗的策略之一。
As the features of angiogenesis inhibitors are of low toxicity and have less acquired resistance, it comes to a new strategy to suppress tumor growth by restraining angiogenesis.
透明质酸盐在创面修复过程中具有清创、抗炎、促进创伤愈合重要作用,其代谢产物能够促进血管生成及成纤维细胞增殖,调控胶原合成。
HA plays an important role in debridement, anti-inflammatory, promoting wound healing. Its metabolites can promote angiogenesis, proliferation of fibroblasts, modulate the synthesis of collagen.
透明质酸盐在创面修复过程中具有清创、抗炎、促进创伤愈合重要作用,其代谢产物能够促进血管生成及成纤维细胞增殖,调控胶原合成。
HA plays an important role in debridement, anti-inflammatory, promoting wound healing. Its metabolites can promote angiogenesis, proliferation of fibroblasts, modulate the synthesis of collagen.
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