耐多药结核病是由对多数有效抗结核病药物（异烟肼和利福平）都具有耐药性的细菌引起的。
MDR-TB is caused by bacteria that are resistant to the most effective anti-TB drugs (isoniazid and rifampicin).
掌握异烟肼、利福平作用机制、临床应用、主要不良反应。 熟悉其它抗结核病药及抗麻风病药的临床选药。
Chapter 45 Antituberculous drugs and Antileprosy drugs Master the mechanisms of action, therapeutic applications and major adverse reactions of isoniazid and rifampin.
去年世卫组织抗结核耐药报告说明了在一般人群中结核病耐多药情况已达到前所未有的最高水平。
Last year, the WHO report on anti-TB drug resistance documented the highest levels of multi-drug resistance ever recorded in a general population.
耐多药结核病是耐药结核病的一种特殊形式，由于某一杆菌至少对异烟肼和利福平这两个最强有力的抗结核药品产生耐药而造成。
MDR-TB is a specific form of drug-resistant TB due to a bacillus resistant to at least isoniazid and rifampicin, the two most powerful anti-TB drugs.
目的了解抗结核药致肝损害危险因素，为结核病合理化疗提供依据。
Objective to understand risk factors of hepatic toxicity of antituberculosis agents and provide scientific basis for tuberculosis chemotherapy.
目的：了解当前结核病对一线及二线抗结核药物的耐药性及耐多药情况，为结核病防治提供依据。
Objective: To investigate the resistance status of Bacillus tuberculosis to anti?tuberculosis drugs of fist and second ranks in use, and so as to provide basic data for tuberculosis (TB)prevention .
目的：了解当前结核病对一线及二线抗结核药物的耐药性及耐多药情况，为结核病防治提供依据。
Objective: To investigate the resistance status of Bacillus tuberculosis to anti?tuberculosis drugs of fist and second ranks in use, and so as to provide basic data for tuberculosis (TB)prevention .
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