用途usage：新型的抗癫痫药。
目的：探讨抗癫痫药对癫痫患者骨代谢影响。
Objective: To study the bone metabolism in patients with epilepsy after antiepileptic drugs (AEDs) treatment.
加巴喷丁是一种新型抗癫痫药，其化学结构与GABA相似。
Gabapentin is a new anti-epileptic agent whose chemical structure resembles that of GABA.
丙戊酸钠作为常用一线抗癫痫药，目前在临床的应用较为广泛。
As a first - line agent for treating epilepsy, valproate sodium is widely used in clinic.
已经有证据表明抗癫痫药可致畸，并且与增加先天畸形风险相关。
There is evidence that certain antiepileptic drugs (AEDs) are teratogenic and are associated with an increased risk of congenital malformation.
单用一种抗癫痫药，能取得良好的效果者，就不必进行联合用药。
With a single antiepileptic drug, can achieve good results who do not have the combination therapy.
暴露在丙戊酸钠下具有比其他抗癫痫药更高的出生缺陷，比如卡马西平和拉莫三秦。
That valproate exposure carries a higher risk of birth defectsthan other antiepileptics, such as lamotrigine and carbamazepine, is not new knowledge, Torbjorn Tomson, M.D.
对难治性癫痫病人来说，一种药不能控制发作，需联合第二种抗癫痫药。
Of refractory epilepsy patients, a drug can not control the seizures, antiepileptic drugs to be joint second.
本品可单独应用或与其他抗癫痫药合用于治疗局限性及全身性癫痫发作。
It can be used alone or combined with other antiepileptic drugs for the treatment of focal and generalized seizures.
两者最常见的致敏药物是解热镇痛药，其次是抗生素类和镇静抗癫痫药。
The drug most commonly involved was analgesics, followed by the antibiotics and sedative anticonvulsants.
到他27岁时，癫痫病每周要发作11次，过量服用抗癫痫药让他近乎中毒。
By the time he was 27 he was having as many as 11 seizures a week and was on near-toxic doses of anti-convulsants.
前言：目的：对目前应用的抗癫痫药进行评价，以期对其临床应用提供参考。
OBJECTIVE: to evaluate the current application situation of the antiepileptic drugs so as to provide reference for their clinical use.
新型抗癫痫药的问世和应用，给儿童癫痫患者的治疗带来了希望和更多的选择。
The appearance and application of new antiepileptic drug, brought hope to the children with epilepsy to entitle them more chances for selection.
目的：探讨抗癫痫药高敏综合征(AHS)的临床特点、诊断、发病机理及治疗。
Objective: To discuss the clinical features, diagnosis, pathogenesis and treatment of antiepileptic drug hypersensitivity syndrome (AHS).
虽然总体上看来抗癫痫药的认知副作用比较轻，但这些副作用还是很值得临床医生去关注。
Although the cognitive effects of AEDs are generally modest, these effects can have clinical impact, and worthy much of our attention.
抗癫痫药的疗效和副作用存在着显著的个体差异，现认为药物基因组学在个体差异中发挥了重要作用。
Curative and side effect of antiepileptic drugs has distinct individual difference. The pharmacogenomics plays an important in individual difference.
FDA将与制药企业共同协作在抗癫痫药产品说明书上补充这个新信息，并预期变更整类产品的说明书。
FDA and pharmaceutical companies will work together in anti-epileptic drug Manual added on this new information, and is expected to change the entire category of product brochures.
已往研究多认为所有抗癫痫药物都有认知方面的副作用；新型抗癫痫药比传统抗癫痫药的认知损害较少并且轻。
According to the past studies, all of the AEDs produce cognitive effects compared to the non-drug conditions, and the new AEDs have fewer and less effects on cognition than the older AEDs.
在妥泰联用抗癫痫药丙戊酸盐的女性中出生缺陷发生率最高，后者已被许多研究结果和癫痫数据库认定与出生缺陷相关。
The birth defect rate was highest among women who took Topamax in combination with the epilepsy drug valproate, which has been linked to birth defects in numerous studies and epilepsy databases.
偏相关分析显示，患儿生活质量与父母焦虑、抗癫痫药数量、首次发作年龄、发作频率和病程等呈显著相关（P<0.05）。
Parental anxiety, the number of AEDs, onset age, seizuring frequency and duration were significantly associated with quality of life of children(P<0.05).
经严格的入选及排除标准，确定未用任何抗癫痫药物者入选单药治疗组；目前正在应用2种以下正规抗癫痫药物者入选托吡酯添加治疗组。
The patients who have no AEDs enter monotherapy group, and the patients who were curing by not more than 2 drugs enter concomitant therapy group by strict standard.
对于怀孕的女性，您需要告诉她们北美抗癫痫药（NAEED）怀孕登记相关信息，并且鼓励他们拨打电话1-888-233-2334进行登记。
You should inform patients of the North American Antiepileptic Drug (NAEED) Pregnancy Registry and encourage patients who become pregnant to enroll by calling 1-888-233-2334.
这一公告还表示，辉瑞还非法地宣传了抗精神病药齐拉西酮（Geodon），抗生素利奈唑酮（Zyvox）以及抗癫痫药物普瑞巴林（Lyrica）。
The settlement announcement said Pfizer also illegally promoted the anti-psychotic drug Geodon, the antibiotic Zyvox and the anti-epilepsy drug Lyrica.
目的抗癫痫药物可以引起甲状腺激素水平改变，本研究旨在探讨抗癫痫药卡马西平(CBZ)、丙戊酸钠(VPA)对男性癫痫病人甲状腺激素水平的影响。
Objective: Antiepileptic drugs (AEDS) may affect serum thyroid hormone concentration. this study aimed to evaluate thyroid function in men taking carbamazepine (CBZ), or valproate (VPA) for epilepsy.
目的抗癫痫药物可以引起甲状腺激素水平改变，本研究旨在探讨抗癫痫药卡马西平(CBZ)、丙戊酸钠(VPA)对男性癫痫病人甲状腺激素水平的影响。
Objective: Antiepileptic drugs (AEDS) may affect serum thyroid hormone concentration. this study aimed to evaluate thyroid function in men taking carbamazepine (CBZ), or valproate (VPA) for epilepsy.
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