对核苷类化合物糖环部分的化学改造一直是发现新的具有抗病毒、抗肿瘤或其他生物活性的核苷类先导化合物的重要途径之一。
The chemical modification of sugar moiety in nucleoside or nucleotide is always an important way to discover new lead compounds with anti-viral, anti-tumor and other biological activities.
克来夫定为嘧啶类似物,对HBV具有持续有效的抗病毒活性。
Clevudine is a pyrimidine analogue with potent and sustained antiviral activity against HBV.
结果表明:提取物的抗病毒活性因提取溶剂和提取方法的不同而异。
The results showed that antiviral substance activity is dissimilar based on extracts from walnut peel with different solvent and methods.
在不破坏其活性必需集团的前提下,将两种化合物连接起来,很有可能得到抗病毒能力更强的新的化合物。
A novel compound with a much higher anti-virus activity may be got by the conjunction of the two compounds without destroying the active domain.
所述化合物干扰端粒末端转移酶和反转录酶的活性,并可以用作抗病毒、抗菌和抗癌剂。
The compounds interfere with the activities of telomerase and reverse transcriptase, and are useful as antivirals, antibacterials and anticancer agents.
鬼臼毒素及其衍生物是一类具有显著生理活性的木脂素类化合物,其主要生理活性表现为抗肿瘤活性及抗病毒活性。
Podophyllotoxin as well as its derivatives exhibit a pronounced biological activity mainly as antitumor agents, which is a good source of the aryltetralin lignan.
所有的分离出来的代谢物中,只有(-)-1显示出来抗真菌、抗病毒以及杀活性,而后者似乎是(-)- 1的一种新功能。
Among all the isolated metabolites, only (-) -1 showed antifungal, antibacterial, and insecticidal activity. This latter activity appears to be a new property attributed to (-) -1.
实验证明该化合物具有显著的抗病毒活性。
Test shows that said compound possesses significant activity of virus-resistance.
说明化合物A是乙酸乙酯萃取物中主要抗病毒活性成份之一。
The result indicated that the compound A was one of the main antiviral components in acetate extract.
说明化合物A是乙酸乙酯萃取物中主要抗病毒活性成份之一。
The result indicated that the compound A was one of the main antiviral components in acetate extract.
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