目的：构建噬菌体人源抗独特型抗体库。
AIM: To construct phage human anti idiotypic antibody library.
对近年来抗独特型抗体的研究进展进行综述。
The recent advances in the research of anti-idiotypic antibody were introduced.
抗独特型抗体免疫治疗是肿瘤治疗的新途径。
Immunization with anti-idiotypic antibodies represents a novel approach to active immunotherapy for tumors.
目的：探讨抗独特型抗体对小鼠特异性低免疫反应状态的诱导作用。
Objective:To investigate the induction effect of anti-idiotypic antibodies on mice specific low immune reactive state.
目的探讨卵巢癌抗独特型抗体6b11表位多肽与诱导免疫应答之间的关系。
Objective to explore the relationship between the immune response induced by 6b11 anti-idiotypic antibody and its epitope peptides.
目的：探索日本血吸虫单克隆抗独特型抗体NP30对血吸虫虫卵肉芽肿细胞凋亡的影响。
Objective:To study the effect of monoclonal anti-idiotypic antibody NP30 on apoptosis of egg granuloma cells in mice infected with Schistosoma japonicum.
但由于目前所使用的抗独特型抗体多为鼠源性，用于人体可产生人抗鼠抗体反应，从而影响疗效。
But at present, many anti idiotypic antibodies are mouse original antibodies, which can cause human anti mouse antibody (HAMA) response and decrease the curative effect.
黑色素瘤抗独特型抗体疫苗能模拟肿瘤相关抗原，激发机体的抗肿瘤免疫应答，已在许多动物实验和临床试验中得到证实。
It has been demonstrated that anti-idiotypic antibody vaccines against melanoma can mimic tumor-associated antigens and activate anti-tumor immune responses in many animal models and clinical trials.
以上研究证明日本血吸虫单克隆抗独特型抗体np30具有较好的抗感染免疫和抗病免疫功效，可作为日本血吸虫病疫苗候选分子。
Anti-idiotypic antibody NP30 was confirmed with protective immunity of both anti-infection and anti-pathology and may act as a vaccine candidate for schistosomiasis japonica.
以上研究证明日本血吸虫单克隆抗独特型抗体np30具有较好的抗感染免疫和抗病免疫功效，可作为日本血吸虫病疫苗候选分子。
Anti-idiotypic antibody NP30 was confirmed with protective immunity of both anti-infection and anti-pathology and may act as a vaccine candidate for schistosomiasis japonica.
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