在南非追踪研究最近被感染了因突变而减毒的艾滋病毒而且无上述优势人类白细胞抗原的21名妇女。
The South African study tracked 21 women without the beneficial form of HLA who were recently infected with the weakened strain of HIV.
抗原，CD59；糖尿病；突变；cho细胞；转染；抗补体活性。
Antigens, CD59; Mutation; CHO cells; Transfection; Anticomplement activity.
目的：对炭疽毒素保护性抗原（PA）的不同结构域进行了缺失突变，以期找到免疫原性降低而功能变化不大的PA蛋白突变体。
Objective:To find protective antigen(PA) defective mutants of anthrax toxin with the same function as PA but with low immunogenicity, different domains of PA were mutated.
在无HLAA2表型的感染者中，其感染后5年病毒抗原表位肽段既无共有序列的变异，也无琥珀突变。
However, in the HLA A2 - individual, the epitope had neither variation nor amber mutation in 5 years after infection.
符合条件的患者乙肝表面抗原阳性的代偿性肝脏疾病的男性和女性谁是至少6个月以上的，给予拉米夫定和HBV聚合酶基因突变。
Eligible patients were hepatitis B surface antigen-positive men and women with compensated liver disease who were given lamivudine at least more than 6 months and had HBV polymerase gene mutation.
基因组学的到来使高通量筛选肿瘤特异性转录和突变成为可能，随即能够识别异常的共用及单一肿瘤相关抗原。
The advent of genomics allows a high-throughput screening for tumor-specific transcripts and mutations, with that identifying novel Shared and unique TAA.
该突变体的溶栓活性没有明显变化，而突变体的抗原性显著降低。
Although there is no significant change with thrombolytic activity of the mutant, antigenicity of the mutant decreases significantly.
本发明属突变或遗传工程领域，本发明公开了一种葡激酶的低抗原性突变体的制备方法及用途。
This invention belongs to mutation or genetic engineering field, which discloses a preparation of low antigen mutation of staphylokinase and its usage.
本发明属突变或遗传工程领域，本发明公开了一种葡激酶的低抗原性突变体的制备方法及用途。
This invention belongs to mutation or genetic engineering field, which discloses a preparation of low antigen mutation of staphylokinase and its usage.
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