探索具有可放大的、非特异性纯化目的抗体片段的工艺路线。
To explore the antibody fragment purification technics that is befitting for production scale.
竞争抑制实验表明所获人源抗体片段与亲本鼠源单抗结合同一抗原表位。
Binding competition studies demonstrated that they bound the same epitope of the Ag as the parental Ab.
该接受基团可以是抗体、抗体片段、抗生物素蛋白、链霉抗生物素蛋白、或生物素基序。
The receptive group can be an antibody, a fragment of an antibody, an avidin, a streptavidin, or a biotin moiety.
本发明涉及重组多肽，特别是结合纤连蛋白的Ed-B-同种型并可阻断其功能的抗体或抗体片段。
The invention relates to recombinant polypeptides, in particular antibodies or antibody fragments, which are able to bind the ED-B isoform of fibronectin and block the function thereof.
本发明也揭示包含所述抗rage抗体及其RAGE结合抗体片段的医药组合物及其用于治疗RAGE相关疾病的用途。
Also disclosed are pharmaceutical compositions comprising such anti-RAGE antibodies and RAGE-binding antibody fragments thereof, and their use for treatment of RAGE related diseases.
重组抗体及其片段在正在进行诊断和治疗的临床试验中占所有生物蛋白的30 %以上。
Recombinant antibodies and their fragments now represent over 30% of all biological proteins undergoing clinical trials for diagnosis and therapy.
本发明也提供结合至该TF的人源化抗体及其片段。
Also provided are humanized antibodies and fragments thereof that bind to the TF.
前言： 目的：自制凝血酶原片段F1+2单克隆抗体，探讨其在血栓性疾病中的诊断作用。
Objective:To prepare a monoclonal antibody against prothrombin fragment 1+2(F1+2) and study its diagnostic effect in patients with thromboembolism.
同时也提供该核酸序列编码的多肽及其衍生物、变异体或上述多肽的片段、多聚核苷或抗体。
Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody.
本发明揭示与晚期糖化终产物受体(RAGE)特异性结合的抗体及其RAGE结合片段。
Antibodies that bind specifically to receptor for advanced glycation end products (RAGE) and RAGE-binding fragments thereof are disclosed.
特别的，细胞结合剂是识别并结合CD38蛋白的单 克隆抗体、其表位结合片段。
In particular, the cell binding agent is a monoclonal antibody, and epitope-binding fragments thereof, that recognizes and binds the CD38 protein.
表明可合并组成一段含启动子、起始密码子和NKND四个氨基酸的678个碱基的单克隆抗体M26～32抗原决定簇基因片段。
A combined 678 bp sequence which containing promoter, initiation codon and NKND sequence can be used for further research of target antigen gene of pan species monoclonal antibody M26~32.
表明可合并组成一段含启动子、起始密码子和NKND四个氨基酸的678个碱基的单克隆抗体M26～32抗原决定簇基因片段。
A combined 678 bp sequence which containing promoter, initiation codon and NKND sequence can be used for further research of target antigen gene of pan species monoclonal antibody M26~32.
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