方法建立经典的大鼠抑郁模型。
建立大鼠抑郁模型。
采用孤养结合CUMS方式建立大鼠抑郁模型。
CUMS with solitary condition was taken to establish rat depression model.
目的研究白芍解郁颗粒对小鼠抑郁模型的影响。
AIM To study the effect of Beishao Jieyu Granules in depression mice.
结论HPE在行为绝望动物抑郁模型上有明显抗抑郁作用。
Conclusion HPE possessed obviously antidepressant effect in the behavioral despair animal models of depression.
模型制备:采用慢性不可预见性应激法造成大鼠抑郁模型。
Model preparation: The depression model rat was produced by chronic unpredictable stress.
方法:采用大鼠慢性应激抑郁模型、灌胃给药、行为学及免疫组织化学方法。
METHOD: This study adapted the depression rat model of chronic stress, behavior and immunohistochemistry.
主要观察指标:突触体5 -羟色胺重摄取抑制活性,抑郁模型小鼠静止时间。
MAIN OUTCOME MEASURE: the 5-ht reuptake inhibition in synaptosomes and the immobility time in depression models.
目的观察复方刺蒺藜苷对慢性轻度不可预见性应激抑郁模型大鼠行为学的影响。
Objective:To observe the effect of tribuloside on behavior and neurogenesis in dentate gyrus of chronic stress depression rats.
目的:探讨电针百会、太冲穴对抑郁模型大鼠海马组织中NGF、BDNF的影响。
Objective:To investigate the effects of electroacupuncturing acupoints Baihui, Taichong on NGF, BDNFv of hippocampus of depression model rats.
目的:建立利血平抑郁模型的合适剂量,观察不同剂量利血平对大鼠自发活动的影响。
Objective: to establish the suitable dosage of reserpine for animal model of depression, and to observe the different dosage of reserpine on locomotion activity in rats.
目的:观察脑缺血后抑郁模型大鼠下丘脑酪胺酸羟化酶(TH)表达及益肾调气方药的干预作用。
Objective:To observe the expression of Tyrosine Hydroxylase(TH) of Hypothalamus in post-stroke depression rat model and effects of Yishen Tiaoqi decoction.
方法:以多种复合刺激交替进行的方法建立慢性应激抑郁模型,并取脾脏进行淋巴细胞体外培养。
Methods:Chronic stress of depression model was made by alternate mulriple stimulate, and lymphocyte of spleen was cultured in vitro.
方法:(1) 动物模型:连续21天慢性轻度不可预见性应激配合孤养方法建立大鼠抑郁模型。
METHODS: (1) The chronic stressed depression rats were established by chronic unpredictable mild stress and separation after 21 days.
刺五加胶囊可能通过改变抑郁模型大鼠结肠组织mda,SOD和COX2的表达来改善其结肠的功能。
Ciwujia capsule can protect the colon tissue of depressed rats by changing the levels of MDA, SOD and the expression of COX 2.
结论TT在多种抑郁模型上具有一定的抗抑郁作用,可能与增强去甲肾上腺素能及5 -羟色胺能神经系统有关。
Conclusion TT has antidepressant effects in various depression mouse models. Its mechanism may be related to the reinforcement of ne and 5-ht nerves system.
目的:探讨自拟舒肝解郁灵对抑郁模型小鼠行为及血清中白细胞介素2 (IL - 2)、白细胞介素6 (IL - 6)和皮质醇的影响。
Objective To study the effects of Shugan Jieyuling self-made (SJSM) on behavior, levels of serum IL-2, IL-6 and cortisol in depression model mice.
目的:建立一种有效、可行的更年期抑郁症动物模型。
AIM: To establish an effective and feasible involutional depression animal model.
结论:该动物模型生殖内分泌激素与神经递质两方面均较好地反映了更年期抑郁症的病理生理变化。
CONCLUSION:This animal model reflects the physiopathological changes of menopause depression disease in the aspects of productive endocrine hormone and neurotransmitter.
在应激性抑郁研究中,常用的动物模型包括行为绝望模型、习得无助模型、慢性应激模型等。
Animal models of Behavioral Despair, Learned Helplessness, and Chronic stress, etc., are widely used to study stress-induced depression.
目的建立脑卒中后抑郁状态动物模型。
Objective To establish the animal model of post-stroke depression.
认知模型认为抑郁个体存在认知加工的偏向,但是,相对于外显认知,抑郁的内隐认知研究较少。
Cognitive models maintain that depressed individuals demonstrate biases in information processing, but the implicit cognition of depression has been less studied than explicit cognition.
方法用小鼠尾悬挂实验和大鼠强迫游泳实验模型对HPE的抗抑郁作用进行研究。
Methods By using the mouse tail suspension test and rat forced swimming test models of depression, the antidepressant effects of HPE were observed.
方法采用慢性综合应激法建立抑郁大鼠模型。
Methods Rat was treated with chronic and comprehensive stress to form depression model.
对数线性模型分析结果表明,医学生睡眠质量与焦虑、抑郁之间两两相关。
The analyzing result of log-linear model shows that there are correlations among sleep quality and anxiety, depression in medical college students.
结论在脑出血的基础上给予慢性不可预见的温和应激,能建立较理想的脑出血后抑郁动物模型。
Conclusion It is an ideal method for establishing the animal model of post-encephalorrhagia depression to give chronic unpredictable mild stress to rats on the basis of cerebral hemorrhage.
结论:复方柴胡口服液对“行为绝望”动物模型有抗抑郁作用。
Conclusion: Compound Radix Bupleuri Oral Liquids has an antidepressant-like effect in the despair animal models of depression in mice.
目的:采用高通量基因芯片观察大鼠抑郁症模型基因表达的变化,结合基因功能分类体系探讨抑郁症的发病机制。
AIM: To observe the alteration of gene expression of depression rat models by gene chips of high flux, and explore the pathogenesis of depression combining with classification system of gene function.
目的研究抑郁症模型鼠海马神经元细胞的凋亡,探讨海马损害的病理生理机制。
Objective to study the pathophysiological mechanism about the apoptosis of neurons in the rat hippocampus of depression model.
目的:观察针刺对抑郁症模型大鼠行为学和前额皮质单胺类神经递质的影响,分析针灸治疗抑郁症可能的作用机制。
AIM: To observe effects of acupuncture on praxiology and monoamine neurotransmitter in frontal cortex of depressed model rats and analyze the mechanism of acupuncture on treating depression.
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