又名为抑肽酶的特拉·西罗,已经上市13年。
Trasylol, also known as aprotinin, has been on the market for 13 years.
前言: 目的:探讨抑肽酶致过敏性休克的防治。
OBJECTIVE:To discuss the prevention and cure of anaphylactic shock caused by trasylol.
此外,抑肽酶是一种具有抗原性的动物源性蛋白质。
Moreover, aprotinin is a protein of animal origin and has antigenic properties.
目的探索大剂量抑肽酶对缺血再灌注离体鼠心的影响。
Objective: This study was designed to assess the protective effects of high-dose aprotinin on isolated rat hearts from ischemia reperfusion injury.
结论:抑肽酶对大鼠慢性肝损伤具有明显的治疗作用。
Conclusion Aprotinin has therapeutic functions on chronic hepatic injury in rats.
结论提示抑肽酶对小鼠急性肝损伤具有明显的保护作用。
Conclusion Aprotinin has protective functions on mice with acute liver injury in mice.
应用抑肽酶和乌司他丁,更好地做好血液保护和心肌保护。
Ulinastatin and aprotinin were good for myocardial protection and blood protection.
目的:探讨抑肽酶与止血环酸对心脏直视术后出血的影响。
Objective:To compare the efficacy of aprotinin with tranexamic acid on postoperative bleeding in cardiac patients operated under cardiopulmonary bypass.
最近有报道显示抑肽酶与接受心脏手术的患者不良预后相关。
Background Aprotinin has recently been associated with adverse outcomes in patients undergoing cardiac surgery.
目的探讨抑肽酶对胸外科围手术期的凝血-纤溶系统的影响。
Objective To study aprotinin 's effect on blood coagulation and fibrinolysis system.
结论:止血环酸与抑肽酶同样明显减少首次心脏直视术后出血。
Conclusion: Tranexamic acid is as effective as aprotinin on the reduction of postoperative blood loss in patients undergoing direct vision cardiac surgery.
再次手术及进行复杂手术的病人抑肽酶的可能的好处应该达最佳。
The potential benefit of aprotinin should be optimal in patients undergoing reoperation and complex surgery.
目的探讨在脊柱矫形手术应用大剂量抑肽酶减少出血量的疗效。
Objective Inquiry into curative effect that apply the big amount of Aprotinin to reduces bleed in the spinal column orthopedics surgical operation.
目的:研究抑肽酶对体外循环心内直视手术患者肾功能的影响。
Objective Aprotinin is a serine protease inhibitor undergoing metabolism in the kidney, its elimination is almost entirely carried out by the kidney.
目的临床观察抑肽酶在小儿体外循环手术中对肺损伤的保护作用。
OBJECTIVE To observe the clinical effect of aprotinin on lung protection in infants undergoing cardiopulmonary bypass.
目的了解抑肽酶对心瓣膜置换术患者围术期全身炎症应答的影响。
Objective to explore the effect of Aprotintin on whole-body inflammatory response in the patients with cardiac valve replacement during perioperative period.
目的:探讨抑肽酶对食管癌切除围手术期的凝血—纤溶系统的影响。
Objective: To study the effect of aprotinin on blood coagulation and fibrinolysis system.
目的:优化融合表达抑肽酶基因工程菌的发酵条件,分离纯化抑肽酶。
Aim: to optimize the fermentation conditions of engineering bacteria expressing fusion proteins composed of aprotinin and to purify aprotinin.
皮下胰岛素抵抗的治疗包括使用抑肽酶、抗凝剂、肌内注射胰岛素等。
The treatment of the problem involves Aprotinin, anticoagulant and intramuscular injection of insulin.
目的:分析生长抑素类似物、抑肽酶治疗急性水肿性胰腺炎的临床疗效。
Objective: to evaluate the clinical curative effect of somatostatin and gabexate mesilate in the treatment of acute edematous pancreatitis.
目的探讨抑肽酶血液麻醉在脊柱外科手术中的使用价值及对凝血功能的影响。
Objective To investigate the role of blood anesthesia with aprotinin during the vertebral column surgery and the effect on the blood coagulative function.
说明抑肽酶引起的不良反应通常都较严重,应重视对抑肽酶不良反应的监测。
Conclused ADRs caused by aprotinin was severe usually, so it was very important to reinforce monitoring clinically.
结果:抑肽酶组较对照组术后失血和血制品的使用明显减少(P<0.01)。
Results:In patients given aprotinin, postoperative blood loss and use of blood products were significantly low (P< 0.01).
目的:观察小剂量抑肽酶加自体输血对体外循环围术期凝血和纤溶功能的影响。
Objective: to observe the effects of low dose aprotinin plus autotransfusion of blood on coagulation and fibrinolysis during and after cardiopulmonary bypass.
结论:硫酸镁与抑肽酶均能改善脊髓缺血损伤后的神经功能恢复,减轻病理损伤。
CONCLUSION: Both Mg2SO4 and aprotinin can remarkably improve the recovery of nerve function and lessen pathological damage post spinal cord ischemia injury.
结果与结论:静脉滴注抑肽酶发生过敏性休克的几率较高,应做好预防和抢救的准备。
RESULTS&CONCLUSION:The incidence rate of anaphylactic shock from trasylol by intravenous drip is quite high, thereby preparation of prevention and emergency treatment should be ready.
目的探讨抑肽酶联合控制性降压在鼻窦内窥镜手术中的使用价值及对凝血功能的影响。
Objective To investigate the role of aprotinin with control blood pressure during endoscopy surgery operation of sinusitis and the effect on the blood coagulative function.
目的观察体外循环(CPB)心脏瓣膜置换手术中使用大剂量抑肽酶对心肌的保护作用。
Objective To investigate the myocardial protective effects of large dose of aprotinin on myocardium during cardiac valvular replacement operation under cardiopulmonary bypass (CPB).
目的观察术前单次应用小剂量抑肽酶对脑膜瘤切除术患者术中出血量和术后脑水肿的影响。
Objective To observe the effects of preoperative aprotinin infusion on blood loss and brain edema in patients undergoing meningioma resection.
目的观察术前单次应用小剂量抑肽酶对脑膜瘤切除术患者术中出血量和术后脑水肿的影响。
Objective To observe the effects of preoperative aprotinin infusion on blood loss and brain edema in patients undergoing meningioma resection.
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