结论:高免疫原性的抑制素表达质粒的构建为利用抑制素基因免疫技术诱导单胎动物生多胎奠定了基础。
Conclusion: the fusion gene expression vector was successfully constructed, and it set up the basis of inhibin gene immunization to induce multiple bear for single birth animals.
ACN对大鼠睾丸中ABP和抑制素基因表达水平有影响,提示丙烯腈对睾丸中支持细胞可能有损伤作用。
The results indicate that ACN could induce changes in the levels of ABP and inhibin gene expression in testes of male SD rats, that may damage Sertoli cells in testes.
他们发现,史蒂芬.奎克罹患“心肌梗塞,第二类糖尿病和其他几种癌症的基因发病风险在上升”,最后使得奎克决定服用预防这类疾病的抑制素药物。
They found he had an “increased genetic risk for myocardial infarction, type 2 diabetes, and some cancers, ” and Quake decided to take a prophylactic statin as a result.
首先,他引入了一种能够导致肌生成抑制素的受体受到抑制的基因,使肌肉细胞的细胞膜表面的分子收到停止生长的信息。
First, he has introduced a gene that turns out a stunted version of the myostatin receptor, the molecule that sits in the surface membrane of muscle cells and receives the message to stop growing.
这种抑制作用就是为什么胰岛素基因在胰岛腺中试开启的而在大脑中是关闭的。
This silencing is why the DNA for, say, insulin is turned off in brain cells but active in pancreas cells.
这两种基因产生与上述受体结合的大量蛋白质,压制和削弱有功能肌肉生长抑制素分子的作用。
These churn out proteins which bind to the receptors, swamping and diluting the effect of functional myostatin molecules.
研究表明,番茄发育过程中对基因转录水平进行的调控是决定类胡萝卜素构成和含量的主要手段,但转录后调控和产物反馈抑制也不容忽视。
Experimental results showed that gene expression control at the transcriptional level was a key regulation for determining composition and content of carotenoids in ripe fruit.
目的探讨凋亡基因对大鼠心肌梗死的表达及血管紧张素转化酶抑制剂(acei)的干预作用。
Objective to investigate the expression of apoptosis - related genes in rats with myocardial infarction and effects of ACEI.
目的探讨反义vegf基因和内皮抑素基因联合转染在抑制肿瘤血管生成和肿瘤生长转移中的作用。
Objective to explore the co operative inhibitory effect of antisense VEGF gene and endostatin gene transfection on tumor angiogenesis, tumor growth and metastasis of lung cancer.
结论DNR在耐药细胞中的异常分布与肿瘤细胞耐药基因形成有关,槲皮素在体外直接抑制MRP1功能,恢复DNR在细胞内的分布。
Conclusion Altered subcellular distribution of DNR in resistant cell line was related to MDR gene formation. Quercetin could inhibit MRP1 function and could restore the subcellular DNR distribution.
目的研究携带血管抑素K1-5基因的腺病毒载体对其对血管内皮细胞增殖的抑制作用。
Objective To investigate the suppression effects of a adenovirus vector containing angiostatin K1-5 gene to the proliferation and migration of vascular endothelial cells.
结论:胃炎康加维酶素可能是通过抑制胃黏膜癌基因蛋白的异常表达而发挥治疗胃癌前病变的作用。
Conclusion:The effect of Weiyankang plus gastrone on precancerosis of gastric cancer may due to repress the abnormal expression of oncogene proteins in gastric mucosa.
本文综述了包括肿瘤坏死因子抑制剂、白细胞介素1抑制剂、干细胞移植及基因治疗等生物治疗在类风湿性关节炎治疗中的作用。
This article reviews the effect of biotherapy in ra including tumor necrosis factor inhibitor, IL-1inhibitor, stem cell transplantation genetic therapy and so on.
结果人血管抑素基因可明显的抑制卵巢癌裸鼠移植瘤生长。
Results Human angiostatin gene could suppress the growth of transplanted tumor from ovarian neoplasm nude mice obviously.
方法建立人卵巢癌裸鼠动物模型,检测腺病毒介导的人血管抑素基因对肿瘤生长的抑制作用。
Methods A human ovarian cancer model using a nude mice was built to test the suppressive effect of human angiostatin gene mediated by adenovirus on the tumor growth.
采用同源克隆及基因组步移的方法,分离克隆了牙鲆肌肉生长抑制素(MSTN)基因。
Myostatin(MSTN)gene was isolated from Japanese flounder(Paralichthys olivaceus)by homology cloning strategy and genome walking.
获得敲除肌肉生长抑制素(MSTN)基因的猪胎儿成纤维细胞。
The objective of this study is to get MSTN knock-out porcine fetal fibroblast.
通过建立荷人胃癌的裸鼠动物模型,分析基因转导后动物肿瘤细胞中内皮抑素的表达情况及对肿瘤的抑制作用。
Animal model of gastric cancer bearing nude mice were established to assay the expression of mouse endostatin and inhibition for tumor cell in vivo.
如果刺激时间延长到14天,非生理浓度葡萄糖均表现为胰岛素基因的抑制作用。
When islets were stimulated as long as 14 days, all non-physiologic concentrations of glucose showed suppressive effects in insulin gene expression in a dose-dependent manner.
血管紧张素转换酶抑制剂(acei)治疗后冠心病组各型肱动脉内皮依赖性舒张功能与治疗前比较均有显著性改善,其中DD基因型改善最为明显。
After the therapy with angiotensin converting enzyme inhibitor (ACEI), the endothelium-dependent vasodilation function was improved in the coronary groups and especially for the DD group.
ARF是生长素信号转导途径中的关键因子,它可以接受生长素传递的信号,启动或是抑制下游基因的表达。
ARF is the key factor in auxin signal transduction pathway, which can receive the signals caused by auxin and activate or repress the expression of the backward genes.
细胞核中,抑制素通过与转录因子如rb和p 53相互作用来调节靶基因的转录(2,5)。
In the nucleus prohibitins interact with transcription factors such as Rb and p53 to regulate target gene transcription (2, 5).
结论:醛固酮抑制3t3- L1脂肪细胞内脂素的基因表达和分泌。
CONCLUSION: Aldosterone inhibits the gene expression and protein secretion of visfatin in 3t3-l1 adipocytes.
研究血管抑素基因联合化疗药物顺铂对人卵巢癌细胞SKOV3诱导的裸鼠腹腔肿瘤和腹水的抑制作用及其相关机理。
To observe the effects of angiostatin gene therapy combined with chemotherapy on intraperitoneal tumor and ascites fluid induced by human ovarian epithelial carcinoma cell line SKOV3 in nude mouse.
同时,低于抑制浓度的四环素和红霉素对PA0011基因的表达有明显的增强作用。
At the same time, expression of PA0011 was found to increase over time in the presence of sub-inhibitory tetracycline and erythromycin concentration.
本文综述了肌肉生长抑制素蛋白的结构、活性调控、信号转导途径以及肌抑素基因的表达和生物学作用。
In this paper the formation, activity regulation and signal transduction pathway of myostatin were reviewed. At the same time, the gene expression and biological effect of myostatin were discussed.
本试验旨在通过基因工程方法获得重组肌肉生长抑制素蛋白。
This experiment was conducted to gain the recombinant myostatin by technique for gene engineering.
本试验旨在通过基因工程方法获得重组肌肉生长抑制素蛋白。
This experiment was conducted to gain the recombinant myostatin by technique for gene engineering.
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