• 结论:高免疫原性抑制素表达粒的构建为利用抑制素基因免疫技术诱导动物胎奠定基础

    Conclusion: the fusion gene expression vector was successfully constructed, and it set up the basis of inhibin gene immunization to induce multiple bear for single birth animals.

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  • ACN大鼠睾丸ABP抑制素基因表达水平有影响,提示丙烯腈对睾丸中支持细胞可能损伤作用

    The results indicate that ACN could induce changes in the levels of ABP and inhibin gene expression in testes of male SD rats, that may damage Sertoli cells in testes.

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  • 他们发现,史蒂芬.奎克罹患“心肌梗塞,第二类糖尿病其他几种癌症的基因发病风险上升”,最后使得奎克决定服用预防疾病的抑制素药物。

    They found he had an “increased genetic risk for myocardial infarction, type 2 diabetes, and some cancers, ” and Quake decided to take a prophylactic statin as a result.

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  • 首先引入一种能够导致肌生成抑制素受体受到抑制基因使肌肉细胞细胞膜表面分子收到停止生长信息

    First, he has introduced a gene that turns out a stunted version of the myostatin receptor, the molecule that sits in the surface membrane of muscle cells and receives the message to stop growing.

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  • 这种抑制作用就是为什么胰岛基因胰岛腺中试开启的大脑关闭的。

    This silencing is why the DNA for, say, insulin is turned off in brain cells but active in pancreas cells.

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  • 两种基因产生与上述受体结合大量蛋白质压制削弱有功能肌肉生长抑制素分子作用

    These churn out proteins which bind to the receptors, swamping and diluting the effect of functional myostatin molecules.

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  • 研究表明,番茄发育过程中基因转录水平进行调控决定胡萝卜构成含量主要手段,但转录后调控和产物反馈抑制也不容忽视。

    Experimental results showed that gene expression control at the transcriptional level was a key regulation for determining composition and content of carotenoids in ripe fruit.

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  • 目的探讨凋亡基因大鼠心肌梗死表达血管紧张转化酶抑制剂(acei)干预作用

    Objective to investigate the expression of apoptosis - related genes in rats with myocardial infarction and effects of ACEI.

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  • 目的探讨反义vegf基因内皮抑基因联合转染抑制肿瘤血管生成和肿瘤生长转移中的作用

    Objective to explore the co operative inhibitory effect of antisense VEGF gene and endostatin gene transfection on tumor angiogenesis, tumor growth and metastasis of lung cancer.

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  • 结论DNR细胞中的异常分布肿瘤细胞耐药基因形成有关槲皮在体外直接抑制MRP1功能恢复DNR在细胞内的分布。

    Conclusion Altered subcellular distribution of DNR in resistant cell line was related to MDR gene formation. Quercetin could inhibit MRP1 function and could restore the subcellular DNR distribution.

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  • 目的研究携带血管抑K1-5基因腺病毒载体对其血管内皮细胞增殖抑制作用

    Objective To investigate the suppression effects of a adenovirus vector containing angiostatin K1-5 gene to the proliferation and migration of vascular endothelial cells.

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  • 结论:胃炎加维酶可能通过抑制黏膜基因蛋白异常表达而发挥治疗胃癌前病变的作用。

    Conclusion:The effect of Weiyankang plus gastrone on precancerosis of gastric cancer may due to repress the abnormal expression of oncogene proteins in gastric mucosa.

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  • 本文综述包括肿瘤坏死因子抑制白细胞介1抑制干细胞移植基因治疗生物治疗类风湿性关节炎治疗中的作用

    This article reviews the effect of biotherapy in ra including tumor necrosis factor inhibitor, IL-1inhibitor, stem cell transplantation genetic therapy and so on.

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  • 结果血管抑基因明显抑制卵巢癌裸鼠移植生长

    Results Human angiostatin gene could suppress the growth of transplanted tumor from ovarian neoplasm nude mice obviously.

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  • 方法建立卵巢癌裸鼠动物模型检测腺病毒介导血管抑基因肿瘤生长抑制作用

    Methods A human ovarian cancer model using a nude mice was built to test the suppressive effect of human angiostatin gene mediated by adenovirus on the tumor growth.

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  • 采用同源克隆基因步移的方法,分离克隆了牙鲆肌肉生长抑制素MSTN基因

    Myostatin(MSTN)gene was isolated from Japanese flounder(Paralichthys olivaceus)by homology cloning strategy and genome walking.

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  • 获得除肌肉生长抑制素MSTN基因胎儿成纤维细胞

    The objective of this study is to get MSTN knock-out porcine fetal fibroblast.

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  • 通过建立荷人胃癌裸鼠动物模型分析基因转导后动物肿瘤细胞内皮表达情况肿瘤抑制作用

    Animal model of gastric cancer bearing nude mice were established to assay the expression of mouse endostatin and inhibition for tumor cell in vivo.

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  • 如果刺激时间延长到14,非生理浓度葡萄糖均表现胰岛基因抑制作用

    When islets were stimulated as long as 14 days, all non-physiologic concentrations of glucose showed suppressive effects in insulin gene expression in a dose-dependent manner.

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  • 血管紧张转换抑制(acei)治疗冠心病各型动脉内皮依赖性舒张功能治疗前比较均有显著性改善,其中DD基因型改善最为明显。

    After the therapy with angiotensin converting enzyme inhibitor (ACEI), the endothelium-dependent vasodilation function was improved in the coronary groups and especially for the DD group.

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  • ARF生长信号转导途径中的关键因子可以接受生长传递信号启动或是抑制下游基因表达

    ARF is the key factor in auxin signal transduction pathway, which can receive the signals caused by auxin and activate or repress the expression of the backward genes.

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  • 细胞核中,抑制素通过转录因子rbp 53相互作用调节基因的转录(2,5)。

    In the nucleus prohibitins interact with transcription factors such as Rb and p53 to regulate target gene transcription (2, 5).

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  • 结论醛固酮抑制3t3- L1脂肪细胞内脂基因表达分泌

    CONCLUSION: Aldosterone inhibits the gene expression and protein secretion of visfatin in 3t3-l1 adipocytes.

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  • 研究血管基因联合化疗药物顺铂卵巢癌细胞SKOV3诱导的裸鼠腹腔肿瘤腹水抑制作用及其相关机理。

    To observe the effects of angiostatin gene therapy combined with chemotherapy on intraperitoneal tumor and ascites fluid induced by human ovarian epithelial carcinoma cell line SKOV3 in nude mouse.

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  • 同时,低于抑制浓度四环红霉PA0011基因表达有明显的增强作用

    At the same time, expression of PA0011 was found to increase over time in the presence of sub-inhibitory tetracycline and erythromycin concentration.

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  • 本文综述了肌肉生长抑制蛋白结构活性调控信号转导途径以及肌抑基因表达生物学作用

    In this paper the formation, activity regulation and signal transduction pathway of myostatin were reviewed. At the same time, the gene expression and biological effect of myostatin were discussed.

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  • 试验旨在通过基因工程方法获得重组肌肉生长抑制素蛋白

    This experiment was conducted to gain the recombinant myostatin by technique for gene engineering.

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  • 试验旨在通过基因工程方法获得重组肌肉生长抑制素蛋白

    This experiment was conducted to gain the recombinant myostatin by technique for gene engineering.

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