结果：端粒酶反义寡聚脱氧核苷酸能诱导人胃癌细胞凋亡，抑制端粒酶活性。
Telomerase activity were detected by TRAPELISA. Results: Telomerase antisense oligodeoxynucleotides acted as a specific growth inhibitor to gastric cancer cell line.
结果：两种药物均具有抗qgy细胞增殖、阻滞细胞周期、诱导凋亡及抑制端粒酶活性的作用。
Results: These two drugs could inhibit the proliferation of QGY cells, block the cell cycle, induce its apoptosis and inhibit the activity of telomerase.
结果：ICA可明显抑制端粒酶活性，对白血病细胞均有较明显的诱导分化和抑制增殖作用，且与A TRA合用可产生明显的协同效应。
Results: ICA could inhibit the telomerase activity and induce the differentiation and restrain the proliferation of HL-60 cells. The effect was promoted by ATRA.
端粒酶活性的抑制可以导致细胞的衰老和死亡。
Inhibition of telomerase activity leads the cells to senescence and death.
目的：研究嵌合寡核酸对端粒酶活性的抑制作用。
Objective: To investigate the inhibitory effect of telomerase activity by chimeric oligonucleotide .
对端粒酶活性的抑制可能是两种药物发挥抗肿瘤作用的机制之一。
The inhibition of telomerase activity may be one of the mechanisms of the anti-cancer effect of the two drugs.
她分析了它们的组织来检测老鼠的端粒酶是否完全有活性，而人的有是否被抑制。
She analyzed their tissues to determine if the telomerase was fully active in them, as it was in mice, or suppressed, as it is in humans.
目的研究逆转录酶抑制剂(azt)对卵巢肿瘤细胞端粒酶活性的影响。
AIM to study the effect of inhibition of telomerase activity by reverse transcriptase inhibitors (AZT) on ovarian cancer cells in vitro.
结论：P 53蛋白能够抑制人瘢痕疙瘩成纤维细胞端粒酶活性。
Conclusion: P53 protein significantly inhibits telomerase activity in human keloid fibroblasts.
细胞表现凋亡诱导，且其端粒酶活性受到抑制。
设计针对端粒酶的HDV核酶，观察其对端粒酶活性抑制。
To design HDV ribozyme for human telomerase RNA (hTR) component, and observe its inhibition for telomerase activity. Pseudoknotted g.
设计针对端粒酶的HDV核酶，观察其对端粒酶活性抑制。
To design HDV ribozyme for human telomerase RNA( hTR) component, and observe its inhibition for telomerase activity. Pseudoknotted g.
结果：冬凌草甲素可显著降低K5 6 2细胞的端粒酶活性，抑制细胞的生长，诱导细胞发生凋亡。
Results: Oridonin could decrease the activity of telomerase, as well as cause apoptosis and inhibit the growth of K562 cells significantly.
结果：咖啡酸锗能诱导h 22细胞凋亡以及抑制端粒酶的活性，并与药物浓度有关。
Results: Caffeic acid Ge could induced H22 cells apoptosis and inhibit telomerase activity by different concentrations.
结论DFMO引起的K562细胞生长抑制及凋亡诱导与端粒酶活性抑制有关。
Conclusion: The growth inhibition and apoptosis induction of K562 cells treated by DFMO were associated with suppressed telomerase activity.
该文重点介绍近年来报道的不同结构类型的小分子端粒酶抑制剂，并对其活性及构效关系进行综述。
This review had highlighted recent developments in different chemical types of telomerase inhibitors. The biological activity and the structure-activity relationship aspects were also described.
该文重点介绍近年来报道的不同结构类型的小分子端粒酶抑制剂，并对其活性及构效关系进行综述。
This review had highlighted recent developments in different chemical types of telomerase inhibitors. The biological activity and the structure-activity relationship aspects were also described.
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