成骨细胞分化所需的第二个重要转录因子是一种具有锌指结构的,对骨形成十分重要的转录因子。
A second important transcription factor required for osteoblastic differentiation is osterix.
成骨细胞分化,软骨细胞,脂肪细胞。
结论LPS刺激骨组织发生炎症反应、抑制成骨细胞分化。
Conclusion LPS could involve bone tissue in inflammation and inhibit the differentiation of osteoblast.
而成骨细胞分化过程受到骨基质中一系列激素和因子的精确调控。
The osteoblast differentiation process is precisely controlled by a series of hormone and genes in the bone matrix.
这可能与AOPP直接诱导动脉平滑肌细胞向成骨细胞分化有关。
In vitro AOPP may directly induce the osteoblast differentiation of HASMC.
结论补骨脂乙酸乙酯提取物和乙醇提取物均可促进成骨细胞分化、增殖。
Conclusion Ethyl acetate extract and alcohol extract from Fructus Psoraleae can stimulate the differentiation and proliferation of osteoblasts in vitro.
骨诱导活性是指移植组织通过诱导受体组织的间充质细胞向成骨细胞分化。
The latter is a process whereby the transplanted tissue induces mesenchymal cells of the recipient to differentiate into osteoblastic cells.
结论BMP不仅可诱导间质细胞向成骨细胞分化,而且也可以刺激血管的形成。
Conclusions BMP might not only induce differentiation of mesenchymal cells, but also stimulate the formation of blood vessels.
结论:地塞米松可以诱导骨髓基质细胞向成骨细胞分化,形成骨髓基质成骨细胞。
CONCLUSION: marrow stroma cells can be induced into marrow stromal osteoblasts by dexamethasone to form marrow stroma osteoblasts.
运用原子力显微镜可以清晰地看到MSC在向成骨细胞分化过程中超微结构的变化。
The phenotype changes during the process of MSC differentiation to osteoblast could be distinctly observed under atomic force microscopy.
细胞表面分子的表达在细胞分化过程中呈特征性改变,是成骨细胞分化早期的一个重要标志。
The expression of cell surface antigens during differentiation has characteristic changes, which may be key markers in the early stage of osteoblasts differentiation.
提取的骨髓基质细胞呈贴壁生长,诱导后可向成骨细胞分化,细胞呈成骨细胞形态为梭形和多角形。
BMSC grew by static adherence, differentiated to osteoblasts and had strong capacity of proliferation, the shape of cells was fusiform or polygon, like osteoblasts.
结论接骨中药提取物植入颅骨缺损部位后能促进间充质细胞向成骨细胞分化,从而加速骨缺损的愈合。
Conclusion Local implantation of bone-healing herb extract into skull defect can enhance differentiation of mesenchymal cells to osteoblasts the healing process of bone defects.
研究结果表明:(1)淫羊藿促进骨髓基质细胞向成骨细胞分化的有效部位是乙酸乙酯萃取部位和水提物;
The results showed that:(1) On cellular level, the fraction of ethyl acetate and water extract could promote osteogenic differentiation of MSCs;
细胞水平上淫羊藿乙酸乙酯萃取部位可以促进小鼠骨髓基质细胞向成骨细胞分化而不抑制其向脂肪细胞分化。
On cellular level, the fraction of ethyl acetate could promote osteogenic differentiation and showed no inhibition on adipogenic differentiation of MSCs.
在分化成骨细胞后,有30个或少于30个基因与该蛋白结合。
After differentiation to bone cells, 30 or fewer genes bound to the protein.
结论铁合金颗粒使成骨细胞OPG基因表达下降,使破骨细胞分化、活化功能增强,这可能是导致假体松动的骨溶解机制之一。
Conclusion Titanium alloy particles decrease expression of OPG gene in human osteoblasts, and this may contribute to the differentiation of osteoclasts which may lead to the periprosthetic osteolysis.
脂肪干细胞为多能干细胞,能在体外定向诱导分化为成骨细胞。
Adipose-derived stem cells are multipotential stem cell and can be induced to osteoblast in vitro.
这是一种软组织瘤,肿瘤细胞分化为成骨细胞并形成骨肿瘤。
It is a malignant connective (soft) tissue tumor whose neoplastic cells present osteoblastic differentiation and form tumoral bone.
结论锌能够促进体外培养大鼠成骨细胞的增殖及分化。
Conclusion Zinc could promote proliferation and differentiation of the rat osteoblast in vitro.
而周期性拉伸刺激对成骨细胞的分化、矿化起抑制作用。
Then cyclic stretching inhibited differentiation and mineralization of osteoblasts at all loaded time.
结论:骨碎补水相和醇相提取物中分别存在有较高活性的促成骨细胞增殖、分化和钙化的物质。
Conclusion: in the DFS aqueous-and ethanol-extracts, there are some of the components promoting the proliferation, differentiation and calcification of osteoblast.
目的:探讨染料木素体外对大鼠成骨细胞增殖与分化的影响。
Objective: To study the effects of genistein on proliferation and differentiation of cultured osteoblasts in vitro.
目的:研究辛伐他汀对大鼠成骨细胞增殖和分化功能的影响,探讨其刺激成骨的作用机制。
Objective: to study the effect of simvastatin on osteoblast proliferation and differentiation and to explore the mechanism of stimulation of bone formation by simvastatin.
目的研究致敏淋巴细胞对兔颅骨成骨细胞增殖、分化的作用。
Objective To study the effects of sensitized t lymphocytes on osteoblastic proliferation and differentiation.
结果:二甲胺四环素在体外具有刺激骨髓基质细胞和成骨细胞增殖的作用,但抑制细胞的分化。
Result: minocycline can stimulate the proliferation of osteoblast and marrow stromal cell, but also can restrain the differentiation.
目的:研究外源性牛血浆纤维粘连蛋白对体外培养的大鼠成骨细胞增殖分化的影响。
Objective: To investigate the effects of bovine plasma fibronectin on the proliferation and differentiation of rat osteoblasts.
因此,缺锌能够抑制体外培养大鼠成骨细胞的增殖和分化。
Therefore, it was concluded that zinc deficiency inhibited the proliferation and differentiation of rat osteoblast in vitro.
着重介绍了微重力对骨髓间质干细胞到成熟成骨细胞整个分化过程的影响及其可能机制。
The effects of microgravity on the differentiation process from BMSCs to mature osteoblast and its possible mechanism were emphatically introduced.
结论:活血化瘀汤促进体外培养成骨细胞早期的增殖与分化从而促进骨形成。
Conclusions: HXHY decoction can promote bone formation by accelerating the proliferation and the differentiation of osteoblast in vitro in early period.
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