本文从树突状细胞的来源、分化成熟、抗原提呈机理及抗肿瘤治疗的实验研究、临床应用等方面进行综述。
In this review, we summarize the source, differentiation, antigen presenting mechanism, the experimental and clinical researches on anti tumor therapy of dendritic cells.
目的检测强直性脊柱炎(as)患者关节积液与外周血树突状细胞(DC)的数量变化及成熟度。
Objective To research the amount and maturity of dendritic cell (DC) in joint fluid and peripheral blood of ankylosing spondylitis (AS) patients.
目的：探讨改善外周血来源的树突状细胞（DC）体外培养的方法，以促进DC的成熟并提高其递呈抗原和激发特异性免疫反应的能力。
PART I The Improvement of Dendritic Cell Culture Measures in vitroObjective: Improve the measures of dendritic cell culture in vitro, to increase the rate of mature and function of DC.
结论骨髓间充质干细胞上清可抑制单核细胞来源的树突状细胞的成熟和功能，诱导免疫耐受。
Conclusion Human bone marrow mesenchymal stem cells inhibit maturation and function of monocyte-derived dendritic cells and induce immune tolerance.
结果显示霍乱毒素B能增强树突状细胞的活化与成熟，对其免疫学功能起正性调节作用。
Cholera toxin B can enhance the activation of dendritic cells mature, its immune function from the positive regulatory role.
有趣的是，LCL-1除表达于B细胞，也在不成熟和成熟树突状细胞表达，尤以后者表达水平更高。
In addition to its expression in B cells, LCL-1 is also expressed in immature as well as mature dendritic cells(DC), with higher expression level seen in mature DC.
体外诱导小鼠树突状细胞(DC)，流式细胞术分析DC表型，评价尿酸钠体外对DC成熟的效应。
Dendritic cells (DC) were induced in vitro, the phenotypes of DC were analyzed by flow cytometry and the effect of UANa on DC maturity was evaluated.
SOCS1沉默的树突状细胞能够促进自身成熟并增强其诱导的T细胞的抗肿瘤活性。
SOCS1 silent DC could promote DC maturity and enhance the antitumor response of t cell.
SOCS1沉默的树突状细胞能够促进自身成熟并增强其诱导的T细胞的抗肿瘤活性。
SOCS1 silent DC could promote DC maturity and enhance the antitumor response of t cell.
应用推荐