在应激性抑郁研究中,常用的动物模型包括行为绝望模型、习得无助模型、慢性应激模型等。
Animal models of Behavioral Despair, Learned Helplessness, and Chronic stress, etc., are widely used to study stress-induced depression.
方法利用强迫游泳作为应激源制作慢性应激模型,采用硝酸还原酶法测定各组大鼠血清和海马NO的含量。
Methods The forced swimming was used to set chronic stress model. Using nitric acid deoxidize enzyme method, the NO levels of serum and hippocampus were measured.
方法采用慢性综合应激法建立抑郁大鼠模型。
Methods Rat was treated with chronic and comprehensive stress to form depression model.
焦虑组大鼠即为以焦虑为主要表现的慢性情绪应激模型。
Rats in the anxiety group were the chronic emotional stress models with the main manifestation of anxiety.
结论在脑出血的基础上给予慢性不可预见的温和应激,能建立较理想的脑出血后抑郁动物模型。
Conclusion It is an ideal method for establishing the animal model of post-encephalorrhagia depression to give chronic unpredictable mild stress to rats on the basis of cerebral hemorrhage.
方法:采用大鼠慢性应激抑郁模型、灌胃给药、行为学及免疫组织化学方法。
METHOD: This study adapted the depression rat model of chronic stress, behavior and immunohistochemistry.
方法建立慢性心理应激模型,进行6周游泳训练:测定各组大鼠血清皮质醇、IL - 2、IL - 6的含量。
Methods To construct chronic psychological stress model and carry out swim for 6 weeks in rats. The contents of cortisol, IL-2 and IL-6 were detected.
探讨慢性束缚应激大鼠模型的中医证治相关性。
Explore and discuss the correlation of syndrome with treatment of rats model of chronic immobilization stress.
方法:以多种复合刺激交替进行的方法建立慢性应激抑郁模型,并取脾脏进行淋巴细胞体外培养。
Methods:Chronic stress of depression model was made by alternate mulriple stimulate, and lymphocyte of spleen was cultured in vitro.
模型制备:采用慢性不可预见性应激法造成大鼠抑郁模型。
Model preparation: The depression model rat was produced by chronic unpredictable stress.
目的建立慢性心力衰竭急性应激状态的大鼠模型并进行评价。
Objective To establish the rat model of acute stress during chronic heart failure and evaluate it.
方法:(1) 动物模型:连续21天慢性轻度不可预见性应激配合孤养方法建立大鼠抑郁模型。
METHODS: (1) The chronic stressed depression rats were established by chronic unpredictable mild stress and separation after 21 days.
方法:观察药物对小鼠水浸应激性溃疡、无水乙醇性溃疡、慢性乙酸烧灼性溃疡模型和大鼠胃蛋白酶、胃酸活性的影响。
Methods: All of the mice were divided into three groups and induced by water immersion, pure alcohol damage and chronic acetic acid damage respectively.
在慢性应激大鼠抑郁症模型中,甘丙肽及其受体2在部分脑区的高表达提示甘丙肽很有可能参与了应激过程中神经元功能的调制。
The high expression of galanin and galanin receptor-2 in some brain area suggested that galanin probably take part in the modulation of the function of neurons during the stress process.
而慢性应激是抑郁症的主要发病诱因,慢性应激抑郁症模型被公认为是研究抑郁症的理想模型。
Chronic stress is the primary inducement for depression. Chronic mild stress model is a idea model for the study of depression.
目的观察复方刺蒺藜苷对慢性轻度不可预见性应激抑郁模型大鼠行为学的影响。
Objective:To observe the effect of tribuloside on behavior and neurogenesis in dentate gyrus of chronic stress depression rats.
方法:采用应激性溃疡和慢性乙酸溃疡大鼠模型,观察舒胃散治疗慢性胃炎、胃溃疡的药理作用;
Methods:Taking some stress ulcer and chronic acetic ulcer rats as a model, observing Shuweisan s pharmacological action on treating chronic gastritis and stomach ulcer;
方法:采用应激性溃疡和慢性乙酸溃疡大鼠模型,观察舒胃散治疗慢性胃炎、胃溃疡的药理作用;
Methods:Taking some stress ulcer and chronic acetic ulcer rats as a model, observing Shuweisan s pharmacological action on treating chronic gastritis and stomach ulcer;
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