目的探讨膦甲酸钠治疗慢性重型乙型肝炎的疗效及其不良反应。
To observe the clinical effect and adverse effect of foscarnet sodium in treating patients with chronic severe hepatitis B.
方法36例慢性重型乙型肝炎患者随机分为2组。
Methods 36 patients with chronic severe hepatitis B were randomly divided into 2 groups.
结论恩替卡韦治疗慢性重型乙型肝炎具有较好的疗效和安全性。
Conclusion it can be concluded that Entecavir has good therapeutic efficiency and safety in the treatment of chronic severe hepatitis b.
结论TLR2和TLR4可能与慢性乙型肝炎及慢性重型乙型肝炎的发病有关。
Conclusion TLR2 and TLR4 may have a role in the pathogenesis of chronic hepatitis B and chronic severe hepatitis B.
目的研究激活诱导细胞死亡（AICD）现象在乙型肝炎慢性化和重型化机制中的意义。
ObjectiveTo study the significance of AICD(activation-induced cell death) in the pathogenesis of chronic hepatitis B and chronic severe hepatitis B.
ETV治疗慢性重型乙型肝炎有较好的安全性。
ETV has good security in the treatment for chronic severe hepatitis B.
结果自正常对照组到慢性乙型肝炎组及慢性重型乙型肝炎组外周血清IL-6水平均依次升高，且各组间比较均具有显著性差异；
Results The level of serum IL-6 increased gradually and significantly from the group of healthy control to the group of patients with chronic hepatitis B and patients with chronic severe hepatitis B.
结果自正常对照组到慢性乙型肝炎组及慢性重型乙型肝炎组外周血清IL-6水平均依次升高，且各组间比较均具有显著性差异；
Results The level of serum IL-6 increased gradually and significantly from the group of healthy control to the group of patients with chronic hepatitis B and patients with chronic severe hepatitis B.
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