目的探讨接种大剂量卡介苗活菌对晚期恶性黑色素细胞瘤的疗效和技术细节。
Objective To discuss the effects and technological details of vaccination of large dose of BCG live vaccine treating late stage of melanoma.
方法对4例恶性黑色素细胞瘤转移或术后复发患者接种大剂量卡介苗活菌的长期疗效进行观察和总结。
Method 4 cases of melanoma with metastasis or recurrence after operations were vaccinated with large dose of BCG live vaccine. The long term efficacy was observed and summarized.
2008年举行活动这天确诊的病例中，3000多例为基底细胞癌(非黑色素瘤类)，354例为恶性黑色素瘤，这是最致命的皮肤癌类型。
Of the cases identified on the campaign day in 2008, more than 3000 were basal cell carcinomas (non-melanomas) and 354 were malignant melanomas, the most deadly type of skin cancer.
淋巴瘤、白血病、恶性黑色素瘤和肉瘤都开始于极微小的事件——一个细胞发生了变异（用拉丁语说，就是omniscellulae cellula e cellula）。
Lymphomas, leukemias, malignant melanomas, sarcomas all begin with that microscopic accident, a mutation in one cell: omnis cellula e cellula e cellula.
“我们中的许多人认为，包含了免疫系统攻击癌细胞的这一联合治疗方法，最终将被证明对控制癌症最有效，如恶性黑色素瘤”，他说。
"Many of us believe that a combined approach that includes an immune system attack on cancer cells will ultimately prove to be most useful in controlling cancers such as melanoma," he tells WebMD.
小细胞癌常无明显的大核仁（而恶性黑色素瘤常有），偶尔伴有核内假包涵体。
Small cell carcinomas usually do not show large prominent nucleoli, whereas melanomas often do, accompanied by occasional intranuclear pseudoinclusions.
结论证实人恶性黑色素瘤a375细胞膜上表达MC 1r蛋白。MC1R基因的成功克隆为其进一步研究提供了必要条件。
Conclusion MC1R protein was successfully expressed on the membrane of human melanoma cell line A375. It provided a basis for the further study on MC1R.
目的研究次级淋巴组织趋化因子(SLC)基因转染对小鼠恶性黑色素瘤细胞生物学特性的影响。
Objective To investigate the effects of secondary lymphoid organ chemokine (SLC) gene transfer on the biological characteristics of murine melanoma cells.
黑瘤，黑素瘤含有黑色素的，通常为恶性的肿瘤，由黑素细胞引起且最常见于皮肤中。
A dark-pigmented, usually malignant tumor arising from a melanocyte and occurring most commonly in the skin.
可以导致出血性脑转移瘤的常见恶性肿瘤有黑色素瘤、肾细胞癌、绒毛膜癌、甲状腺癌、肺癌、乳腺癌、以及生殖细胞癌。
The most likely malignancies to produce hemorrhagic metastases are melanoma, renal cell carcinoma, choriocarcinoma, thyroid, lung, breast, and germ cell tumors.
前言：目的：探讨恶性黑色素瘤(恶黑)细胞凋亡、PCNA表达水平关系，找出评价恶黑预后的可靠指标。
Objectiv: to study the relationship between apoptosis and proliferating cell nuclear antigen (PCNA) in malignant melanoma, finding the reliable index of judging malignant melanoma.
结果：基底细胞癌、鳞状细胞癌和恶性黑色素瘤仍是常见的皮肤恶性肿瘤，占本组198例患者的85.6%，共169例。
Results Basal cell caicinoma, squamous cell caicinoma and malignant melanoma were still common malignant tumor on skin, and they occupied 85.6%(169/198) in this group.
肿瘤细胞表达基质金属蛋白酶类物质和勃附分子说明了恶性黑色素瘤组织存在血管生成拟态形成的物质基础。
TIMP, MMP-2,1C AM were secreted by the tumor cells can boost the adhere of tumor cells and matrix remold and turn into the substance base of vasculogenic mimicry .
肿瘤细胞表达基质金属蛋白酶类物质和勃附分子说明了恶性黑色素瘤组织存在血管生成拟态形成的物质基础。
TIMP, MMP-2,1C AM were secreted by the tumor cells can boost the adhere of tumor cells and matrix remold and turn into the substance base of vasculogenic mimicry .
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