提高恶性嗜铬细胞瘤的诊断和治疗水平。
PURPOSE To study means of improving diagnosis and treatment of pheochromocytoma.
病理及随访证实5例为恶性嗜铬细胞瘤。
Of them 5 cases were confirmed as malignant pheochromocytoma.
方法总结12例恶性嗜铬细胞瘤患者临床资料。
Methods 12 cases of malignant pheochromocytoma surgically treated were reviewed.
结论恶性嗜铬细胞瘤经手术切除后，症状可以长期缓解。
CONCLUSIONS Surgical excision of malignant pheochromocytoma can achieve long term remission of symptoms.
一想到嗜铬细胞瘤一定要记得10%这个数值：10%的肿瘤是双侧的，10%发生于儿童，10%的肿瘤是恶性的。
Remember 10% when you think of a pheochromocytoma: 10% are bilateral, 10% are in children, 10% are malignant.
方法用免疫组化和原位杂交研究24例良性肾上腺嗜铬细胞瘤、11例恶性肾上腺嗜铬细胞瘤及11例正常肾上腺组织中vegf的表达情况。
Methods The expression of VEGF in 11 normal adrenal gland, 24 benign adrenal pheochromocytomas, and 11 malignant pheochromocytomas was detected by immunohistochemistry and in situ hybridization.
目的研究血管内皮生长因子(VEGF)在良恶性肾上腺嗜铬细胞瘤中的表达及意义。
Objective to study the expression and significance of vascular endothelial growth factor (VEGF) in benign and malignant adrenal pheochromocytomas.
嗜铬细胞瘤是引起继发性高血压的重要原因，其发病机制目前还不完全清楚，临床上早期鉴别良恶性肿瘤尚有困难。
Pheochromocytoma is an important cause of secondary hypertension, whose pathogenesis is yet to be clarified. It is still difficult to identify malignant cases at early stage.
嗜铬细胞瘤是引起继发性高血压的重要原因，其发病机制目前还不完全清楚，临床上早期鉴别良恶性肿瘤尚有困难。
Pheochromocytoma is an important cause of secondary hypertension, whose pathogenesis is yet to be clarified. It is still difficult to identify malignant cases at early stage.
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