目的建立大鼠难治性癫痫模型并观察其特点及研究多药物耐药蛋白P-糖蛋白表达规律,探讨癫痫耐药机制。
ObjectiveTo establish and research the rat model of refractory epilepsy and investigate the rule of P-glycoprotein expression to make the mechanism of drug resistance clear.
CD44是单一基因所编码的具有高度异质性的单链膜表面糖蛋白家族,在各种组织中广泛表达。
CD44 is a highly heterogeneity family of cell surface proteoglycan, represent products of a single gene and widely expressing in various tissues.
目的探讨过敏性紫癜患者抗血小板抗体、血小板膜糖蛋白表达量的变化及其临床意义。
Objective To investigate the expression and significance of platelet membrane glycoproteins and antiplatelet antibody in patients with anaphylactoid purpura.
目的:证实抗P糖蛋白单克隆抗体(JSB1 )能逆转人肾癌的天然多药耐药(MDR)性。
Purpose:To illustrate anti P gp monoclonal antibody(JSB 1) can reverse multidrug resistance(MDR) of the human kidney cancer.
目的通过检测上皮膜抗原(EMA)、表皮糖蛋白基因(EGP - 2)在乳腺癌组织中的表达,分析它们与乳腺癌临床病理指标的关系,并研究两者表达的相关性。
Objective to investigate the expression of EMA and EGP-2 in breast carcinoma tissues, to analyze their relationship with clinical indexes and to observe the correlation with their expression.
其次,分析药物药代动力学的改变程度是否与P -糖蛋白的遗传多态性有关。
The secondary objective was to determine whether the magnitude of the pharmacokinetic interaction was influenced by P-glycoprotein genetic polymorphism.
越冬幼虫以“小分子糖—氨基酸—糖蛋白”物质系统形成抗寒基质,增强耐寒性。
So there is a substance system including "low molecular weight sugars-amino acid-glycoprotein" which enhances cold hardiness for overwintering larvae.
目的:葡萄柚汁通过对小肠细胞色素P4503A4和潜在性对肠上皮细胞P-糖蛋白的抑制作用,进而影响药物代谢。
Objectives: Grapefruit juice is responsible for drug interactions mediated by intestinal cytochrome P4503A4 inhibition and possibly P-glycoprotein inhibition in enterocytes.
目的:观察不同环境对局灶性脑梗死大鼠梗死灶周围突触膜糖蛋白表达的影响。
Objective: to observe the effects of different environmental interventions on synaptophysin (syn) expressions in peri-infarction cortex of rats after unilateral local cerebral infarction.
方法:检索、概括近几年国内外文献,重点介绍糖蛋白、脂蛋白、胆酸(盐)等载体和手段向肝组织选择性传输活性物质的最新进展。
METHODS:By indexing and summarizing literatures of the last few years all over the world, tight attention was paid to the newest progress in glycoprotein, lipoprotein, bile acid(salt), etc.
本文将对目前进行深入研究的几种血小板膜糖蛋白的结构、功能及其多态性进行论述。
This review covers the structure, function and polymorphism of several platelet membrane glycoproteins which are deeply researched.
不同亚型间的埃博拉病毒的氨基酸序列同源性较差。结论埃博拉病毒糖蛋白的氨基酸序列比较保守,不易发生变异。
But the amino acid sequences of different subtypes weren't highly homologous. Conclusion amino acid sequences of glycoprotein of Ebola virus are conservative.
CSFV囊膜糖蛋白E2是诱导中和抗体及激发保护性免疫应答的主要抗原蛋白。
Envelope glycoprotein E2(gp55) of Classical swine fever virus(CSFV) is the most antigenic protein being responsible for eliciting neutralizing antibodies and conferring protective immunity.
CA125是一种糖蛋白,是上皮性卵巢癌尤其是浆液性腺癌的主要标记。
CA125 is a tumour marker usually associated with ovarian epithelial malignancies. Serum assays are widely used to detect this protein in the monitoring of ovarian cancers.
CA125是一种糖蛋白,是上皮性卵巢癌尤其是浆液性腺癌的主要标记。
CA125 is a tumour marker usually associated with ovarian epithelial malignancies. Serum assays are widely used to detect this protein in the monitoring of ovarian cancers.
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