• 功能周期蛋白和周期蛋白依赖激酶形成的异源三聚体存在化学计量关系

    It functions in stoichiometric relationships forming heterotrimeric complexes with cycling and cyclin-dependent kinases.

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  • 植物aB细胞周期蛋白依赖性激酶直接参与调控细胞周期。

    In plants, a - and B-type CDKs are directly involved in cell cycle regulation.

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  • 目的观察细胞周期蛋白依赖性激酶- 2 (CDK - 2)SH -SY5Y细胞中的表达情况。

    Objective To investigate the expression of cyclin-dependent kinase-2 (CDK-2) gene in SH-SY5Y cells.

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  • 目的探讨翼状胬肉组织中细胞周期蛋白依赖激酶抑制剂P16表达了解翼状胬肉发病机制中的作用

    Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.

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  • 结论翼状胬肉细胞周期蛋白依赖性激酶抑制剂p16的表达可能导致翼状胬肉细胞周期紊乱,其增殖失去控制。

    Conclusion The lower expression of cell circle related kinase inhibitor in pterygium may play an important role on proliferation and pathogenesis of pterygium.

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  • 细胞分裂周期运行不同时转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖激酶CDK复合物来调控

    Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.

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  • 方法应用SP免疫组化法,检测P 21, P27等细胞周期依赖激酶抑制剂增殖细胞核抗原(pcna)角膜上皮不同部位表达情况。

    METHODS: the expressions of CKI, P27, P21 and proliferating cell nuclear antigen (PCNA) were tested in different regions of corneal epithelium by SP immunohistochemistry.

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  • 激酶通过不同途径作用但是现在看来可能可能更多

    Kinases that work through different pathways, however, now seem to hold more potential.

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  • 小鼠模型,GNA11突变诱导自发转移肿瘤激活了丝裂活化蛋白激酶途径

    Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.

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  • 肺癌实验鼠进行实验研究发现依赖蛋白激酶1 (Cdk1)让DNA停止修复

    In experiments on mice with lung tumours the researchers showed that blocking a molecule called Cdk1 also stopped DNA repair.

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  • 与传统的一些药物相比,纳豆激酶具有安全成本可以口服等优点。

    Compared with other medicines which have some attractive traits, for example good safety factor, low cost and can take it orally.

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  • 探讨细胞外信号调节激酶(ERK)卵巢上皮肿瘤组织中的表达及其意义

    To investigate the expression of extracellular signal-regulated kinase (ERK) and its significance in epithelial ovarian tumor.

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  • 我们测试表明IPA - 3PAK1高度选择意味着不太可能随意的关闭其他激酶

    Our tests also demonstrate that IPA-3 is highly selective for PAK1, which means that it is less likely it will also turn off other kinases unintentionally.

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  • 目的观察国产尿激酶(天普乐欣)治疗缺血脑卒中疗效安全

    Objective: To study the curative effect and safety of urokinase (UK) therapy for acute ischemic stroke.

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  • 目的观察静脉注射尿激酶治疗梗死临床疗效安全

    Aim To evaluate the clinical efficacy and safety of thrombolytic therapy for acute cerebral infarction.

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  • 目的探讨大剂量尿激酶早期静脉溶栓治疗梗塞临床疗效安全

    ObjectiveTo determine the clinical curative effect and safety of ultra early intravenous thrombolysis with high-dose urokinase in treatment of acute cerebral infarction.

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  • 目的了解国产尿激酶UK静脉溶栓治疗心肌梗塞AMI)的效果安全

    Objective:To observe the clinical efficacy and safety of intravenous thrombolytic therapy with urokinase (UK) produced by P. R. China in acute myocardial infarction (AMI).

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  • 目的探讨磷脂酰肌醇3激酶(PI 3激酶)银屑病发病相关

    Objective to investigate the correlation between phosphatidylinositol 3 kinase (PI3-kinase) and the pathogenesis of psoriasis.

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  • 目的探讨尿激酶激肽释放酶同时提取可能

    Objective:To explore the possibility of the simultaneous extraction of urokinase and kallikrein.

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  • 目的探讨丝裂活化蛋白激酶(MAPK)高血压心肌肥大中的作用。

    Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.

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  • 目的探讨动脉穿刺尿激酶溶栓治疗糖尿病价值安全

    Objective To discuss the significance of urokinase thrombolysis via femoral artery puncture for the therapy of diabetic feet and its safety.

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  • 目的探讨激酶粗提液小鼠实验高脂血症的血脂作用

    Objective to probe the effect of Nattokinase on reducing serum lipid in the experimental rats with hyperlipemia.

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  • 目的探讨微管引流注入尿激酶治疗结核多房包裹胸腔积液的疗效。

    Objective To explore the role of micro-tube drainage and intrapleural urokinase for patients with tuberculous loculated encysted pleurisy.

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  • 非替尼为选择EGFR一蛋白酪氨酸激酶抑制剂阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡

    Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.

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  • 结论CD 117作为MM肿瘤相关抗原作为靶向信号转导抑制剂酪氨酸激酶选择抑制剂应用有价值标志

    CONCLUSION: CD117 can be regard as the related tumor antigen of MM, and may be a valuable marker in the use of tyrosine kinase selective inhibitors, which inhibit the signal conduct to the target.

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  • 目的观察小剂量尿激酶风湿心脏病二尖瓣狭窄合并心房附壁血栓的溶治疗效果

    Objective To evaluate the thrombolysis effect of low-dose urokinase(UK)on left atrial mural thrombus(LAMT)in patients with mitral stenosis(MS).

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  • 目的观察一次中等剂量尿激酶UK治疗冠状动脉综合征ACS临床效果

    Objective: To observe the clinical effects of low-dose urokinase (UK) in the treatment of acute coronary syndrome(ACS).

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  • 对丁酸转化前后红白血病细胞k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶细胞内源底物进行了研究

    In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.

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  • 目的评价国产尿激酶心肌梗死溶栓治疗中的有效安全

    Objective: To study the efficacy and safety with thrombolysis of urokinase produced in China on acute myocardial infarction.

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  • 目的评价国产尿激酶心肌梗死溶栓治疗中的有效安全

    Objective: To study the efficacy and safety with thrombolysis of urokinase produced in China on acute myocardial infarction.

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