其功能与周期蛋白和周期蛋白依赖性激酶形成的异源三聚体存在化学计量关系。
It functions in stoichiometric relationships forming heterotrimeric complexes with cycling and cyclin-dependent kinases.
在植物中a型和B型细胞周期蛋白依赖性激酶直接参与调控细胞周期。
In plants, a - and B-type CDKs are directly involved in cell cycle regulation.
目的观察细胞周期蛋白依赖性激酶- 2 (CDK - 2)在SH -SY5Y细胞中的表达情况。
Objective To investigate the expression of cyclin-dependent kinase-2 (CDK-2) gene in SH-SY5Y cells.
目的探讨翼状胬肉组织中细胞周期蛋白依赖性激酶抑制剂P16的表达,了解其在翼状胬肉发病机制中的作用。
Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.
结论翼状胬肉中细胞周期蛋白依赖性激酶抑制剂p16的低表达可能导致翼状胬肉细胞周期紊乱,其增殖失去控制。
Conclusion The lower expression of cell circle related kinase inhibitor in pterygium may play an important role on proliferation and pathogenesis of pterygium.
细胞分裂周期运行和不同时相的转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖性激酶(CDK)复合物来调控。
Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.
方法:应用SP免疫组化法,检测P 21, P27等细胞周期依赖性激酶抑制剂和增殖细胞核抗原(pcna)在角膜上皮不同部位的表达情况。
METHODS: the expressions of CKI, P27, P21 and proliferating cell nuclear antigen (PCNA) were tested in different regions of corneal epithelium by SP immunohistochemistry.
激酶通过不同的途径作用,但是,现在看来可能性可能更多。
Kinases that work through different pathways, however, now seem to hold more potential.
在小鼠模型中,GNA11突变诱导了自发转移性肿瘤,激活了丝裂原活化蛋白激酶途径。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
对有肺癌的实验鼠进行实验,研究发现依赖性蛋白激酶1 (Cdk1)让DNA停止修复。
In experiments on mice with lung tumours the researchers showed that blocking a molecule called Cdk1 also stopped DNA repair.
与传统的一些溶栓药物相比,纳豆激酶具有安全性好、成本低及可以口服等优点。
Compared with other medicines which have some attractive traits, for example good safety factor, low cost and can take it orally.
探讨细胞外信号调节激酶(ERK)在卵巢上皮性肿瘤组织中的表达及其意义。
To investigate the expression of extracellular signal-regulated kinase (ERK) and its significance in epithelial ovarian tumor.
我们的测试也表明,IPA - 3对PAK1有高度选择性,这意味着它是不太可能随意的关闭其他激酶。
Our tests also demonstrate that IPA-3 is highly selective for PAK1, which means that it is less likely it will also turn off other kinases unintentionally.
目的:观察国产尿激酶(天普乐欣)治疗急性缺血性脑卒中的疗效及安全性。
Objective: To study the curative effect and safety of urokinase (UK) therapy for acute ischemic stroke.
目的观察静脉注射尿激酶溶栓治疗急性脑梗死的临床疗效及安全性。
Aim To evaluate the clinical efficacy and safety of thrombolytic therapy for acute cerebral infarction.
目的探讨大剂量尿激酶超早期静脉溶栓治疗急性脑梗塞的临床疗效及安全性。
ObjectiveTo determine the clinical curative effect and safety of ultra early intravenous thrombolysis with high-dose urokinase in treatment of acute cerebral infarction.
目的:为了解国产尿激酶(UK)静脉溶栓治疗急性心肌梗塞(AMI)的效果及安全性。
Objective:To observe the clinical efficacy and safety of intravenous thrombolytic therapy with urokinase (UK) produced by P. R. China in acute myocardial infarction (AMI).
目的探讨磷脂酰肌醇3激酶(PI 3激酶)与银屑病发病的相关性。
Objective to investigate the correlation between phosphatidylinositol 3 kinase (PI3-kinase) and the pathogenesis of psoriasis.
目的:探讨尿激酶及激肽释放酶同时提取的可能性。
Objective:To explore the possibility of the simultaneous extraction of urokinase and kallikrein.
目的探讨丝裂素活化蛋白激酶(MAPK)在肾性高血压致心肌肥大中的作用。
Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.
目的探讨经股动脉穿刺以尿激酶溶栓治疗糖尿病足的价值与安全性。
Objective To discuss the significance of urokinase thrombolysis via femoral artery puncture for the therapy of diabetic feet and its safety.
目的探讨纳豆激酶粗提液对小鼠实验性高脂血症的降血脂作用。
Objective to probe the effect of Nattokinase on reducing serum lipid in the experimental rats with hyperlipemia.
目的探讨微管引流并注入尿激酶治疗结核性多房包裹性胸腔积液的疗效。
Objective To explore the role of micro-tube drainage and intrapleural urokinase for patients with tuberculous loculated encysted pleurisy.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
结论CD 117可作为MM的肿瘤相关抗原,也可作为靶向信号转导抑制剂酪氨酸激酶选择性抑制剂应用的有价值的标志。
CONCLUSION: CD117 can be regard as the related tumor antigen of MM, and may be a valuable marker in the use of tyrosine kinase selective inhibitors, which inhibit the signal conduct to the target.
目的观察小剂量尿激酶对风湿性心脏病二尖瓣狭窄合并左心房附壁血栓的溶栓治疗效果。
Objective To evaluate the thrombolysis effect of low-dose urokinase(UK)on left atrial mural thrombus(LAMT)in patients with mitral stenosis(MS).
目的:观察一次性中等剂量尿激酶(UK)治疗急性冠状动脉综合征(ACS)的临床效果。
Objective: To observe the clinical effects of low-dose urokinase (UK) in the treatment of acute coronary syndrome(ACS).
对丁酸钠转化前后的人红白血病细胞林k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶活性及细胞内源性底物进行了研究。
In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.
目的:评价国产尿激酶在急性心肌梗死溶栓治疗中的有效性和安全性。
Objective: To study the efficacy and safety with thrombolysis of urokinase produced in China on acute myocardial infarction.
目的:评价国产尿激酶在急性心肌梗死溶栓治疗中的有效性和安全性。
Objective: To study the efficacy and safety with thrombolysis of urokinase produced in China on acute myocardial infarction.
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