宾夕凡尼亚州大学的研究者说,即便是在目前来说不可治愈的非雄激素依赖性前列腺癌中也是有效的。
It recognized even androgen-independent cancer cells, present when prostate cancer is incurable, the study by researchers at the University of Pennsylvania showed.
病人和方法:作者应用前瞻性设计方法回顾性研究了758例临床局限性或局部进展性前列腺癌病人。
Patients and Methods: A prospectively designed algorithm was applied retrospectively to a cohort of 758 patients with clinically localized or locally advanced prostate cancer.
分离高转移性和低转移性前列腺癌细胞,筛选转移相关基因,为研究前列腺癌的转移分子标志奠定基础。
To isolate high metastatic and low metastatic prostate cancer cells and screen metastasis-associated genes for the purpose of the biomarker exploration of prostate cancer metastasis.
这篇回顾性文章的目的,主要在评估处理局限性前列腺癌方面,冷冻疗法相对于标准治疗所具有的相对临床和经济上的优势。
This review aims to evaluate the relative clinical and economic benefits of cryotherapy compared to standard therapies for the primary treatment of localised prostate cancer.
雄激素受体基因突变、多种途径引起的异常磷酸化激活和共激活物的调节失控等是激素非依赖性前列腺癌形成的主要促成因素。
The mutation of androgen receptor gene, abnormal phosphorylation and abnormal regulation of co-activators contribute to the formation of androgen-independent prostate cancer.
来自其他大型研究的结果,其带有足够数量的晚期和致命性前列腺癌病例数据,可进一步阐述这个问题。”帕克研究小组总结道。
The results from other large...studies, with adequate numbers of advanced and fatal prostate cancers, may shed further light on this question, " Park's team concludes.
来自其他大型研究的结果,其带有足够数量的晚期和致命性前列腺癌病例数据,可进一步阐述这个问题。”帕克研究小组总结道。
The results from other large...studies, with adequate numbers of advanced and fatal prostate cancers, may shed further light on this question," Park's team concludes.
目的:利用RNA干涉技术抑制雄激素受体(AR)的表达,研究AR在激素依赖性和激素非依赖性前列腺癌细胞增殖中的作用。
AIM: To study the role of androgen receptor (AR) in hormone-dependent and hormone-independent prostate cancer cell proliferation by knocking down AR expression with adenovirus-delivered siRNA.
与不饮用咖啡的对象相比,每日饮用6杯或以上咖啡的男性,其罹患各种前列腺癌的风险相对较低,这种效果在致命性前列腺癌上更为明显。
Men who consumed six or more cups per day had a lower adjusted relative risk for overall prostate cancer compared with nondrinkers. The association was stronger for lethal prostate cancer.
大多数雄激素非依赖性前列腺癌均高表达AR和核受体辅活化子、如转录中间因子2(TIF-2),ARA24、PIAS、类固醇受体辅活化子-1(SRC-1)等有力地支持了这个假说。
The "superactive AR"hypothesis was supported by the fact that the majority of AIPC expresses high level of AR and nuclear receptor(NR) coactivators, such as TIF-2, ARA24, PIAS, SRC-1.
一系列令人印象深刻的试点项目,其中包括前列腺癌,已经表明,如果患者了解治疗的临床资料,他们往往选择侵入性较低的治疗方法。
A fascinating series of pilot programs, including for prostate cancer, has shown that when patients have clinical information about treatments, they often choose a less invasive one.
动物蛋白过多,尤其是红肉类,已经同增加心脏病、前列腺癌、乳腺癌,结肠癌的危险性联系到一起了。
Too much animal protein, especially red meat, has been linked with significantly increased risks of heart disease, prostate cancer, breast cancer and colon cancer.
目标是发现那些能够筛查出前列腺癌属于侵袭性和较小侵袭性类型的标记物。“这一标记物在这一方法有助于我们。”
The goal is to find markers that sort prostate cancers into aggressive and less aggressive types, Lichtenfeld said. "This marker may help us in this process, " he added.
作者说,17号染色体的长臂以前在家族相关性研究中(被认为)与前列腺癌有关,但是以前没有报道易感变异。
The long arm of chromosome 17 has previously been associated with prostate cancer in family-based linkage studies, the authors explain, but no susceptibility variants have been reported before now.
以前的研究业已表明,绝经后乳腺癌、前列腺癌和某些类型的结肠癌均与高水平的IGF-1具有相关性,而IGF-1是一种具有较强的促进细胞增殖作用的生长因子。
Past research has linked pre-menopausal breast cancer, prostate cancer and certain types of colon cancer to high levels of IGF-1, a powerful growth factor that promotes cell proliferation.
其他肥胖相关因素影响激素的合成,例如胰岛素,胰岛素样生长因子或瘦素,可能也参与前列腺癌侵袭性形成过程。
Other obesity-related changes in the production of hormones, such as insulin, insulin-like growth factor or leptin, may also be involved in the development of more aggressive prostate cancer.
小鼠视网膜母细胞瘤的治疗成功使科学家对于改善其他转移性实体瘤比如结肠癌,前列腺癌的治疗燃起了信心。
The success with neuroblastoma also suggests this technique might improve the treatment of other solid tumors that metastasize, such as colon and prostate cancer.
RTVP - 1基因导致前列腺癌细胞发生细胞凋亡或称程序性细胞死亡,RTVP - 1基因也激活免疫系统攻击癌细胞。
It causes what is known as "apoptosis" or programmed cell death in prostate cancer cells and also activates the immune system to fight cancer cells.
这意味着男性“可以减少患那些不容易致命的前列腺癌的风险,因此他们可以少接受侵入性治疗,”Andriole说。
That means that men "are less likely to be diagnosed with cancer that is not likely to kill them, so they are less likely to undergo aggressive treatment," Andriole said.
结论三维适形放射治疗中晚期前列腺癌有较好的局部控制效果和较高的安全性,可作为前列腺癌姑息治疗的有效方法之一。
Conclusion the three-dimensional conformal radiotherapy is an effective and safe treatment for prostate cancer. It can be used as good selection of treatment for advanced prostate cancer.
另有研究结果证实那些有家族疾病史的体形肥胖,喜欢吸烟及非洲裔的美国人他们具有患前列腺癌的高风险性。
The results also confirmed other studies' findings with the risk of prostrate cancer higher for men with a family history of the disease, who were obese, smokers or African American.
代谢综合征可能是前列腺癌的保护性因素,随着代谢综合征组份数量的增多,患前列腺癌的风险将减小。
Metabolic syndrome may be a protective factor of prostate cancer, and with the amount of metabolic syndrome component growing, there is less risk of prostate cancer.
代谢综合征可能是前列腺癌的保护性因素,随着代谢综合征组份数量的增多,患前列腺癌的风险将减小。
Metabolic syndrome may be a protective factor of prostate cancer, and with the amount of metabolic syndrome component growing, there is less risk of prostate cancer.
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