ERG11基因启动子突变可能与白念珠菌对氟康唑耐药有关。
The mutation of ERG11 promoter may be associated with the resistance of C. albicans to fluconazole.
念珠菌对氟康唑的耐药率2005年（60.0%）较2004年（33.3%）明显上升（P<0.05）。
The resistence of albicans to fluconazole in 2005 (60%) was significantly higher than that in 2004 (33.3%)(P<0.05).
目的探讨白念珠菌耐药基因CDR1基因上游调控序列对氟康唑耐药的影响。
Objective To appraise the relationship between fluconazole resistance and expression of the CDR1 gene upstream regulation sequence.
目的：研究白念珠菌细胞外磷脂酶活力与其对氟康唑耐药性之间的关系。
Objective: To study the relationship between extracellular phospholipase activity and development of fluconazole-resistance in Candida albicans.
运用牛血清白蛋白培养基方法，分别测定了对氟康唑敏感和对氟康唑耐药的白念珠菌的分泌性蛋白酶活力。
The secretory proteinase activity (SAP) of fluconazole-susceptible Candida albicans isolate and fluconazole-resistant Candida albicans isolate were measured by bovine serum albumin assay.
目的探讨伏立康唑和氟康唑对临床念珠菌的体外抗菌活性。
Objective to discuss the vitro antibacterial activity of Voriconazole and Fluconazole to frequent Candida in clinic.
目的：研究白念珠菌的毒力因子分泌性蛋白酶（SAP）活力与其对氟康唑耐药性形成之间的关系。
Objective: To determine the relationship between virulence production of secreted asparty1 proteinase(SAP) of Candida albicans and the development of the resistance to fluconazole.
结果氟康唑注射液、大蒜素注射液、黄柏提取物 ，在一定浓度下对呼吸道感染白色念珠菌有较明显的抑制作用。
Objective:To observe the ultrastructural changes of candida albicans, candida guilliermondii and candida krusei by the effect of Fluconazole injection made in China.
结论伏立康唑比氟康唑对念珠菌有更高的抗菌活性，在抗念珠菌感染时具有较好临床应用价值。
Conclusions Voriconazole has a stronger antibacterial activity to Candida than Fluconazole, and is worthy of application in clinic for Candida infection.
结论伏立康唑比氟康唑对念珠菌有更高的抗菌活性，在抗念珠菌感染时具有较好临床应用价值。
Conclusions Voriconazole has a stronger antibacterial activity to Candida than Fluconazole, and is worthy of application in clinic for Candida infection.
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