李敏表示，自吞噬是清除细胞内异常蛋白质的唯一途径。
According to Li, autophagy is the only known process that gets rid of abnormal proteins within cells.
这些异常蛋白质倾向于形成有毒的低聚物结构常常导致细胞死亡。
These abnormal proteins tend to organize in toxic oligomeric structures often resulting in cellular death.
阿尔兹·海默氏症主要是由于脑部聚集结块的异常蛋白质，名为be ta淀粉状蛋白斑。
A key aspect of Alzheimer's is sticky clumps of an abnormal protein in the brain called beta amyloid plaques.
正常修复或者消除异常蛋白质的监测系统功能的变化是许多神经变性疾病的基础。
Alterations in the function of the surveillance systems that normally repair or remove abnormal proteins are the basis of many neurodegenerative disorders.
随着生物学研究向分子层次深入，人们已经确知了与各种神经退行性疾病相关的异常蛋白质分子。
With the molecular progress of biological research, the abnormal protein molecules related to various neurodegeneration diseases have been identified.
丘脑是大脑中负责睡眠调控的部分，致死性家族性失眠症正是由于一种异常蛋白质“朊蛋白”在丘脑中的累积产生的。
F.F.I. is caused by anaccumulation within the thalamus — the part of the brain that controlssleep regulation — of abnormal proteins called “prions.”
最后，我们同样论述了氧化应激和老化等影响因素对自噬系统功能的影响和自噬系统处理异常蛋白质的能力。
Finally, we also comment on the effect that aggravating conditions, such as oxidative stress and aging, have on the functioning of the autophagic system and its ability to cope with altered proteins.
李敏表示，自吞噬是清除细胞内异常蛋白质的唯一途径。“增强这一途径可能是治疗帕金森症的关键。”她如是说。
According to Li, autophagy is the only known process that gets rid of abnormal proteins within cells. "Enhancing this pathway may be key to treating Parkinson's," she says.
例如，某些蛋白质的过量会导致细胞异常增殖并癌变；胰岛素蛋白质的缺乏会导致糖尿病。
For example, an excess of certain proteins can cause cells to proliferate abnormally and become cancerous; a lack of the protein insulin results in diabetes.
问题出就出在这些异常折叠的蛋白质。
而对牛奶过敏是指免疫系统对牛奶蛋白质有异常反应。
With a cow's-milk allergy, the immune system has an abnormal reaction to milk protein.
对葡萄糖的研究加上PET扫描就能够对β-淀粉样蛋白成像，这是老年痴呆症病人大脑中一种异常的蛋白质。
Studies with glucose are being supplemented by PET scans that can image beta-amyloid, one of the abnormal proteins in the brain in Alzheimer’s disease.
这个技术检测了免疫系统发现蛋白质之间微小差别及异常抗原抗体反应的能力。
This technique detects the immune system's ability to spot minor differences in proteins and novel antigen-antibody interactions.
例如，现已批准携带人类基因的转基因山羊生产一种人类的蛋白质，用于治疗手术中凝血异常的患者。
Transgenic goats carrying a human gene, for example, are used to produce a human protein now licensed for use during surgery in patients whose blood otherwise fails to clot correctly.
他们发现在正常的细胞中，BCL9L帮助激活一种叫做半胱天冬酶-2的蛋白质以应对异常数量的染色体，引发自毁程序。
They revealed that in normal cells, BCL9L helps activate a protein called caspase-2 in response to an abnormal number of chromosomes, triggering a self-destruct sequence.
一旦在大脑中出现，它便使正常的蛋白质打褶成异常形状。
Once present in the brain it causes normal proteins to refold into the abnormal shape.
这种异常机制是对抑制传递这种激活的ALK蛋白质的疗法是一个明显的靶标。
This abnormality is an obvious target for treatments that inhibit the ALK protein that delivers the trigger.
它使糖、脂肪喝蛋白质的代谢发生异常。
结论在肝纤维化过程中伴有蛋白质合成与分解异常和糖酵解活动增强；
Conclusion (1) Li ver fibrosis is accompanied with abnormal protein synthesis and asition, a s well as the enhanced activity of glycolysis;
阐述了牛乳的加热、原料乳的酸度、异常乳、均质处理及微生物对乳蛋白质的影响。
This article introduces the boiling of milk, the acidity of raw milk, unusual milk, homogen's process and microorganism's influence on lactoprotein.
许多疾病的发生与蛋白质糖链结构异常有关。
Numerous diseases were known to relate with glycan structural abnormality.
目的：探讨人胚胎滋养层细胞中染色体数目异常与着丝粒特异性蛋白质CENP-I表达水平的相关性。
Objective:To observe the expression level of CENP-I gene in human trophoblast cells with numerical chromosomal aberration.
采用了凝胶过滤结合硫酸铵沉淀法从异常复杂的胆汁中成功分离出一种蛋白质。
Biliary protein was isolated and purified by ammonium sulfate fraction and Sephadex G-75 gel filtration column chromatograph from complex pig bile.
载脂蛋白是行使脂类转运功能的血浆蛋白质，其结构和含量异常将影响血脂代谢。
The apolipoproteins play an important role in lipid metabolism, the change of their molecular structure or their expression level significantly changes serum lipids.
载脂蛋白是行使脂类转运功能的血浆蛋白质，其结构和含量异常将影响血脂代谢。
The apolipoproteins play an important role in lipid metabolism, the change of their molecular structure or their expression level significantly changes serum lipids.
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