他们发现p53基因不仅产生大家熟知的p53蛋白质,同时还产生一种p53蛋白质变换“控制开关”的变种——对碘氧基苯甲醚。
They found that the p53 gene makes not only the well-established p53 protein, but also an alternative "control switch" variation of the p53 protein - known as an isoform.
每个相邻基因之间是不能编码蛋白质的dna;相反,它起着基因启动-关闭开关的功能。
Contiguous to each gene is DNA that doesn't code for protein; instead, it functions as the gene's on-off switch.
有一种蛋白质对瓢虫的这两种颜色有影响,并且通过基因开关从一种颜色转换到另一种颜色非常容易。
One protein is responsible for the difference between the two colors, and the genetic switch from one to the other is very simple.
组蛋白还起到了基因开关的作用,因此它们编码的信息可以被复制并且传递到细胞的其它部位。
Histones also play a role in turning genes on so that their coded instructions can be copied and sent to other parts of the cell.
现在,Spiegelman和他的同事们已经确定了两种起分子“开关”作用的蛋白质,它们是产生灰色脂肪的关键。
Now, Spiegelman and colleagues have identified two proteins that act as molecular "switches" to turn on the production of brown fat.
吸食一次可卡因会增加G9a的浓度,然而上瘾之后反而会使其浓度降低,抑制蛋白质的活动,削弱其对基因开关的全面控制。
One-time use of cocaine increases levels of G9a. But repeated use works the other way, suppressing the protein and reducing its overall control of gene activation.
我们的研究显示该独特的蛋白质扳动了多步骤过程中的最后开关,使细胞具有非常强大的多向分化潜能的特征。
Our research shows that this unique protein flips the last switch in a multi-step process that gives cells the very powerful property of pluripotency.
内部传感分子同时也是细菌武器,如弹性蛋白酶的开关,该酶能够破坏肺内的弹性组织。
The QS molecules also switch on bacterial weapons such as 'elastase', an enzyme which breaks down elastic tissue in the lung.
在正常细胞中,MLL与其他四种蛋白联合组成了W-RAD复合体,从而形成了在白细胞形成中所需的一种控制DNA组合的分子开关。
In normal cells, MLL combines with four proteins that comprise the W-RAD group to create a molecular switch that controls DNA packaging events required to form white blood cells.
当这些细胞被激活,它们表面会标记一种免疫检查点蛋白,称为PD1,是“关闭”开关的一种,能够关闭免疫应答。
When these cells are called to activeduty, their extracellular armor is marked with an immune checkpoint protein, atype of "off" switch called PD1 that can be used to shut down the immuneresponse.
癌细胞甲基化水平的异常导致基因开关关闭,使得正常细胞关键蛋白的装配线出现缺陷。
Cancer cells have abnormal levels of methylation, which turns the gene switch off halting the assembly line of critical proteins found in normal cells.
当配体与特定的受体结合,他能稳定蛋白构象,通过打开(或关闭)分子开关控制细胞内不同的分子功能。
When ligands bind to a specific subset of receptors, the ligands stabilize specific protein conformations, turning on (or off) molecular switches that control diverse cellular functions.
他们的研究显示这种蛋白接着能打开分子开关,允许癌细胞侵犯到周围的组织。
Their research suggests that this protein then turns on molecular switches that allow the cancer cells to invade surrounding tissues.
虽然对于珠蛋白基因表达调控及开关的研究已取得许多进展,但至今对于调节这些开关的决定性调节因子仍不明确。
Although advance has been made in the study on control of globin gene expression and switching, key factors of globin gene switching is still unknown till now.
MEF2D是一种转录因子,是一种控制某些基因开关状态的蛋白质。
MEF2D is a transcription factor, a protein that controls whether several genes are turned on or off.
他们发现,大脑中有一个“开关”控制瘦素的作用,它就是一种名为组蛋白去乙酰化酶5(HDAC5)的酶。
They have discovered an enzyme - histone deacetylase 5 (HDAC5) - has a significant influence on the effect of the hormone.
激酶是蛋白开关,它们通过一个称为磷酸化的过程将磷酸基团结合到其他蛋白上并激活这些蛋白。
Kinases are protein switches that activate other proteins by adding a phosphate group to them via a process called phosphorylation.
激酶是蛋白开关,它们通过一个称为磷酸化的过程将磷酸基团结合到其他蛋白上并激活这些蛋白。
Kinases are protein switches that activate other proteins by adding a phosphate group to them via a process called phosphorylation.
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